Mucosal Immunology
@MucosalImmunol
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Official journal for the Society for Mucosal Immunology @socmucimm EIC @BenJMarsland https://t.co/2QZUURlMMd
New York City, NY
Joined July 2017
It's a new year and a new look for #mucosalimmunology! Bookmark our new site for all the latest research, and submit today!.
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Nasal polyp formation during chronic rhinosinusitis can be caused in part by ApoE from M2 macrophages acting on fibroblasts and leading to abnormal remodeling of the extracellular matrix.
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Listen to the latest #MucosalMonday Podcast with Melody Zeng @melodyzeng on how the microbiota influences intestinal health throughout life. On all podcast platforms: @socmucimm @BrunckMarion @Ashu_Mangalam
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Suppressing overactive alveolar macrophages can prevent the exacerbation of allergic asthma:
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#Diabetes can be associated with #periodontal disease; here scRNA profiling identifies immune cell population shifts in diabetes associated mucosal inflammation:.
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A Jak/Stat inhibitor, #Tofacitinib, can suppress IFNg production from ILCs and T cells, reducing tissue damage during ameliorates #Campylobacter
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Mucosal macrophages remain in the intestines due to cues from fibroblast-derived CSF1. These cells are important in resisting salmonella infections: .
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Targeting desmosomes restores hormonal–induced disruption of vaginal epithelial integrity in this work from @RVicetti and colleagues @OhioStateMed
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T cells educated in utero during placental inflammation can promote allergic responses in offspring:
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Florian Rieder @IBD_FloMD and colleagues comment on recent work on immune cell-fibroblast interactions in #Intestinal #Fibrosis
mucosalimmunology.org
Editorial
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RT @socmucimm: It's #MucosalMonday! Check out the latest Mucosal Immunology podcast episode featuring Dr. Isabella Rauch @RauchLab with @….
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It’s #MucosalMonday and the June episode of the Mucosal Immunology Podcast is out with Isabella Rauch, PhD, @BrunckMarion, @Ashu_Mangalam, and more!
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Memory T cell formation and phenotype varies across intestinal compartments:
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The ocular microbiome, ocular plasma cells, and M cells on the tear-duct associated lymphoid tissue - read all the latest👁️Mucosal Immunology online now:
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Even when present, Tregs can be unresponsive and display reduced immunosuppressive function during extensive microbial dysbiosis:
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Is innate immunity of the gut epithelium just blowing in the WNT? Review the latest review on how WNT and BMP pathways determine epithelial identity and responsiveness:
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Intestinal fibrosis during Crohn’s disease can be mediated by inflammatory monocytes via amphiregulin and PI3K/AKT
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Development of IgA based therapeutics could be possible through B cell editing in this work from @Michel_CogneLab and colleagues:
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Predicting success: A multi-omics microbiome signature is associated with the benefits of gastric bypass surgery and is differentiated from diet induced weight loss through 2 years of follow-up
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Mucosal #Tuberculosis vaccination with virulent BCG strains induces protective resident lung CD8+ TRM in part from TGF-β produced by airway epithelial cells in this work from Andreas Kupz and colleagues @AITropHealthMed @RolandRuscher
mucosalimmunology.org
A principal reason for the high global morbidity and mortality of tuberculosis (TB) is the lack of efficacy of the only licensed TB vaccine, Bacillus Calmette-Guérin (BCG), as intradermal BCG does...
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