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Weicheng Li

@WeichengLite

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Postdoc in Jon Ostrem Lab @UCSF. Cooperative ligand | Covalent degrader | Coevolved circuits.

San Francisco, CA
Joined November 2017
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@WeichengLite
Weicheng Li
1 day
RT @qhzheng: 🧵[1/10] A busy week for K-Ras! We report three stories on covalent, mutant-selective targeting of oncogenic K-Ras mutations @A….
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@WeichengLite
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RT @FrankNoeBerlin: BioEmu now published in @ScienceMagazine !! . What is BioEmu? Check out this video: .
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@WeichengLite
Weicheng Li
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RT @RalserLab: When #AlphaFold2 came out, we wondered: Could it help us understand how enzymes evolve? So we tried it—and it worked! https:….
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@WeichengLite
Weicheng Li
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RT @KexinHuang5: 🧬 Excited to open-source Biomni! With just a few lines of code, you can now automate biomedical research with AI agent!. W….
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@WeichengLite
Weicheng Li
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RT @joshim5: Chai-2 is now up on BioRxiv:
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@WeichengLite
Weicheng Li
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RT @AllThingsApx: 🧬Motifs are the new BLAST. Folddisco scans 53M AlphaFold structures for catalytic, binding or allosteric patterns in seco….
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@WeichengLite
Weicheng Li
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RT @kavi_deniz: A new best structure prediction protocol!. Use it on @tamarindbio today: app[dot]tamarind[dot]bio. Thread 👇. On the compreh….
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@WeichengLite
Weicheng Li
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RT @koeng101: As a biologist who codes, I kinda love this analogy. It’s pretty accurate in the base fundamental property that small self co….
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@WeichengLite
Weicheng Li
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RT @karpathy: How to build a thriving open source community by writing code like bacteria do 🦠. Bacterial code (genomes) are:. - small (eac….
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@WeichengLite
Weicheng Li
9 days
RT @fedichev: For decades, scientists and entrepreneurs have debated what the perfect anti-aging drug should look like. Since aging is chro….
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@WeichengLite
Weicheng Li
10 days
RT @ItaiYanai: 'Night science' is what you do when you're not sure what's the question.
Tweet media one
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@WeichengLite
Weicheng Li
12 days
RT @CorinWagen: The past few years of "AI for life sciences" has been all about the models: AF3, NNPs, PLMs, binder generation, docking, co….
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@WeichengLite
Weicheng Li
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RT @ShechnerLab: Hello RNA World! Ever wonder what's "talking to" your favorite transcript, but were too scared to ask? In our review in @C….
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@WeichengLite
Weicheng Li
14 days
RT @afederation: You can’t drug what you can’t see. Until now, the regulome was largely invisible. Today, we’re sharing a new preprint d….
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@WeichengLite
Weicheng Li
15 days
RT @valence_ai: 1/ We are excited to open-source the SynFlowNet-Boltz-2 trainer today! 🧵.
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@WeichengLite
Weicheng Li
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RT @iamjohnnyyu: Completely agree. Pre-training on quality data for the first time allows for context generalization - > an important mil….
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@WeichengLite
Weicheng Li
15 days
RT @chengyenhsieh: 📌Notes on Boltz-2. Just watched the video talk led by @GabriCorso.@jeremyWohlwend, and Saro Passaro that introduced Bolt….
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@WeichengLite
Weicheng Li
16 days
RT @anshulkundaje: This a really exciting leap forward for genomic sequence to activity gene regulation models. It is a genuine improvement….
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@WeichengLite
Weicheng Li
17 days
RT @zakkohane: Remarkable experiments by @mlpowered @wesg52 et al. @anthropic suggesting that LLMs have quasi-symbolic internal representat….
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@WeichengLite
Weicheng Li
18 days
RT @fedichev: Designing small molecules to hit protein targets is the holy grail of drug discovery, but it’s a beast of a problem. For year….
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