BREAKING: Gero Signs Potential Multi-Billion-$  Deal to Fuel Our Mission to Stop Aging  --. A few years ago, my son, aged five at the time, asked what happened to the dinosaurs. After learning their sad story, he told me he wanted to fly to the Moon and defend Earth from falling

. no one knows what entropy really is, so in a debate you will always have the advantage (Von Neumann).

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Every mathematician knows it is impossible to understand an elementary course in thermodynamics (Arnold (1990, p. 163).

The law that entropy always increases, —the second law of thermodynamics—holds, I think, the supreme position among the laws of Nature. If someone points out to you that your pet theory of the universe is in disagreement with Maxwell’s equations—then so much the worse for.

Once you start adding baselines to your pipelines, life gets boring.

LLMs — and especially agentic AI built on them — may be on the brink of real practical importance, with recent advances showing exponential growth in the complexity and duration of tasks they can handle autonomously. With that in mind, I have a question: What’s a great problem

To wrap up our GLP-1RA saga this week, let's zoom in on one of the wildest origins stories in modern medicine. Take a look at the Gila monster (Heloderma suspectum), a chunky, slow-moving lizard from the Southwestern U.S. and Mexico deserts. Believe it or not, one of the first

Liraglutide followed as Victoza in 2010 for diabetes, and semaglutide as Ozempic in 2017—none initially branded or approved for weight loss.That's a fair point—GLP-1 receptor agonists (GLP-1RAs) like exenatide, liraglutide, and semaglutide were indeed first pursued and approved.

RT @cremieuxrecueil: This is true. The former CEO of Novo Nordisk actually said that addressing obesity should be done through a "radical….

Some ask why do we want to build drugs against aging. That’s why, according to others.

Meanwhile, the wellness industry is on the rise. Influencers and activists, many of them young, coach people to "stay young" by sleeping well, dieting, and exercising—this is the same old "aging is a choice" narrative. This "aging as a choice" narrative is further supported by.

We are witnessing a revolution: GLP-1 drugs (like Ozempic, Wegovy, and related semaglutides) are storming the markets, generating over $40 billion in annual sales for Novo Nordisk alone in 2024, with the broader GLP-1 market projected to exceed $50 billion by 2025 as demand

RT @liveforeverclub: 1 month until ARDD 2025 - 12th Aging Research and Drug Discovery Meeting @uni_copenhagen #AgingResearch.Speakers inclu….

When Isaac Asimov first published Foundation in the early 1950s, it was a revolution. Here was a vision of humanity sprawling across the stars, governed not by emperors or empires alone, but by mathematical inevitability — the grand science of psychohistory. It was the book that

Here's where it gets really cool: Sleep pressure (that building urge to nod off) and hunger might share the same cellular roots in mitochondrial dynamics—the cycles of fission (splitting) and fusion (merging) that keep these organelles humming. In the mammalian brain's.

As you know I'm obsessed with power laws in biology, which is a biological consequence of fundamental principles, like energy conservation from the first law of thermodynamics. Geoffrey West showed how highly optimized biological networks—think blood vessels or respiratory

All resources are openly available under the MIT license. Also, given our strong computational results, we are actively looking for collaborators to test and design small molecules!.:rocket: Model & code: :page_facing_up: Full manuscript:.

Friends, as you may know, we recently released ProtoBind-Diff, a diffusion-based generative model that designs SMILES strings of molecules tailored to bind specific protein targets. In benchmarks, we showed very significant enrichment of actives according to state-of-the-art