
Varjosalo_Lab
@Varjosalo_Lab
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Unveiling the secrets of life through proteomics @helsinkiuni, @HiLIFE_helsinki, @BIOTECH_UH, Proteomics, Genomics, Systems biology 🇫🇮🇨🇳🇧🇩🇭🇷🇮🇳🇮🇹🇹🇷
Helsinki, Finland
Joined March 2017
We are excited to announce the winners of the 2025 Q3 Empowerment Award! 🏆 Huge congratulations to all the recipients — it's inspiring to see how this recognition supports your research and propels your careers forward. Keep up the amazing work! 💪 #FeMS #massspectrometry
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DIA-NN 2.2.0 is released! In this update we have focused on analysis speed, which is becoming increasingly critical given the rapid transition to high-throughput proteomics. The new DIA-NN 2.2.0 Enterprise achieves up to ~1.6x median speedup on 64-cores under Windows (please see
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Heading to #ASMS2025 in Baltimore? Join us May 31 for the Evosep User Meeting! Markku Varjosalo of @HiLIFE_helsinki shares insights on automated plasma workflows. Connect, learn, and network—refreshments included! Register here: https://t.co/t3wEywCBDU
#teammassspec #proteomics
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Thread: Multi-omics sounds cool—until you actually try it. Here's are the nuances. 1/ You’ve got RNA-seq. Methylation. Proteomics. Time to “integrate” the data. But how? And why? Let’s break it down.
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New preprint alert! We benchmarked 5 plasma enrichment methods and built an automated, cost-efficient MagNet workflow. Up to 4,200 proteins/sample identified with DIA on timsTOF Pro 2—at just a few dollars/sample. https://t.co/Gi2pQxWmE6
@EvosepBio @bruker
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Felicitaciones! Y hoy celebraron doble con Instruct que incluye @instructhub-ES @CNB_CSIC recibiendo otro de los premios!!
🏅El #CSIC, premio a la trayectoria en igualdad de género de la Unión Europea El galardón reconoce el compromiso que, desde hace más de veinte años, tiene la institución con una ciencia inclusiva de excelencia ➡️ https://t.co/IdtaUVQfBj
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Exciting day for @instructhub in Brussels today!! Thank you to the @EU_Commission for recognising our work!! https://t.co/ztlq5fQsQj
linkedin.com
We are delighted to announce that Instruct has been awarded the Gender Equality Champions prize for 2024 in the Newcomer Category! Thank you very much to the European Commission for recognition of...
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Today we report the directed evolution of HUH (a sequence-sequence covalent protein tag for ssDNA labeling) into rHUH, a sequence-specific covalent protein tag for RNA labeling. rHUH was hard to engineer: the initial HUH template had no RNA activity, so we started with RNA-DNA
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Check out our @Nature review with Tiannan Guo @guomics and Judith Steen @ionicwoman on recent paradigm shifts in MS-based proteomics - where the field stands and where its headed. #Proteomics #AI
https://t.co/xcdi1OI1iV
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As we know, the human plasma🩸 proteome is crucial! The @labs_mann just published a fantastic study in @NatureGenet! And here is our News & Views highlighting the mapping of plasma protein QTLs and why #MassSpec remains a key player: https://t.co/yzdDzcMuyL.
@asmsnews @hupo_org
nature.com
Nature Genetics - Mass spectrometry-based proteomics demonstrated its increasing analytical power and unique strengths in measuring genome-wide plasma proteomes and identifying protein quantitative...
Thrilled to share our latest work published in @NatureGenet today: Plasma proteome variation and its genetic determinants in children and adolescents. 🩸#PediatricProteomics #PlasmaProteomics #pQTL
https://t.co/TU3vKL8ST3 🧵A thread by @hustniu explains below ⬇️
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Bridging the gap: How enhancers cooperate to regulate gene expression over large genomic distances
cell.com
By building synthetic regulatory landscapes, Jensen et al. and Thomas et al. demonstrate in this issue of Molecular Cell that gene expression levels strongly depend on the genomic distance between...
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Yhdistämme voimamme Liigan ja MTV:n kanssa jälleen helmikuussa tärkeän asian puolesta: Munien puolesta -keräyksellä kerätään varoja eturauhas- ja kivessyövän tutkimukseen ja lisätään tietoisuutta miesten yleisistä syövistä. https://t.co/yn5eiRLnXM
#syöpätutkimus #munienpuolesta
syopasaatio.fi
Syöpäsäätiö, Liiga ja MTV mukana, Munien puolesta -keräyksellä kerätään varoja eturauhas- ja kivessyövän tutkimukseen
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Publication Alert 🚨 Check out @C_Lutomski new paper in @NatureChemistry: Defining proteoform-specific interactions for drug targeting in a native cell signalling environment #MassSpec #TopDown #Native @KavliOxford @KavliFoundation @WolfsonCollege
https://t.co/ItsmOuDPxh
nature.com
Nature Chemistry - G protein-coupled receptors and their effectors can now be released directly from a lipid bilayer using infrared irradiation for proteoform-level characterization by native...
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Syöpään sairastumisen riskiin vaikuttaa useiden sairauksien edeltävä esiintyminen. Uudessa suomalaistutkimuksessa yhdistettiin laajamittaisesti kansallisia terveys- ja syöpärekisteriaineistoja. Lue lisää täältä: https://t.co/AyCHn2vkFo
#syöpätutkimus #tiede
sttinfo.fi
Kasvaingenetiikan tutkimuksen huippuyksikön uusi tutkimus tarkasteli syvällisesti muiden sairauksien yhteyttä syöpäriskiin.
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Kicking off the new year properly: In collaboration between the labs of @giuliosf and @alessiociulli we found that the efflux pump ABCC1/MRP1 constitutively restricts PROTAC sensitivity in cancer cells. Out in @CellChemBiol
https://t.co/PbojgA4O6l
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Researcher: "We let the data speak for itself." Earlier that day:
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