Vincent Peng
@TheVincentPeng
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WashU MD/PhD student @TheColonnaLab | Washington University School of Medicine
Joined October 2014
Congratulations to @WUSM MD/PhD candidate Varintra Lander for being awarded the prestigious David M. Kipnis Award in Biomedical Sciences. So very proud of you and a credit to your impressive work. Go @WUSTLdbbs @wustlmstp @WUSTLImmuno
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Happy to announce that our story on #DNAmethylation at #enhancers is out today in @MolecularCell! https://t.co/S1QtIcnUS2 It was a fantastic PhD journey in the lab of @arnaud_kr @EMBL. Follow the 🧵 to find out whether #DNAmethylation is important for enhancer activity: (1/9)
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Latest review on TREM receptors! @NatRevImmunol
https://t.co/ht0ogsXFVX
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A million thanks to all of our collaborators and everyone in the @HumphreysLab for all of their guidance @parkercwilson @YoshiharuMuto Yasuhiro Yoshimura, and @HaojiaWu
Very excited to share our new work led by ⭐️ @nicolas_ledru of @WUSTLmstp describing RENIN, a tool for REgulatory Network INference from single cell multiomic datasets - funded by @ChanZuckerberg 🧬🔥 https://t.co/r2BzmY2KJx
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UptoDate just showed me this in a pop up. Did we know this already, COPD twitter?
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Super excited to share the collaborative work between @vahedilab and Henao-Mejia laboratories revealing the 3D genome organization of innate lymphoid cells. Congrats to everyone in particular Michael, John, Aditi, @ysora90, and Jorge
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My first (co-first author) paper from my postdoc describing the role of Type II cytokine-dependent dendritic cells in thymic immune tolerance is out. https://t.co/7oEm7B0kz0 Thank you @Jamequistlab, @CFI_UMN, @czexpats
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Now our new paper is online. https://t.co/ea44P5CV48 Great collaborative work #2 (many more to follow) with Ansu Satpathy @Satpathology.
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I’m very excited to share our paper published in @NatImmunol describing how T cell lineage fate is determined! https://t.co/fFrfYrMcgZ
nature.com
Nature Immunology - To determine how T cell lineage fates are determined in the thymus, Singer and colleagues generated ‘FlipFlop’ mice with a functionally reversed T cell immune system...
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Check out our new paper on @NatImmunol by @TheVincentPeng in collaboration with @twang5 on the epigenetic landscape of the innate lymphoid cells! https://t.co/EGl1NwPSRQ
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FoxP3 associates with enhancer-promoter loopsto regulate Treg-specific gene expression https://t.co/dUVtnUv9lB
#biorxiv_immuno
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Our new preprint introducing scCUT&Tag-pro (single-cell profiling of histone modifications and cell surface proteins), scChromHMM (inferring chromatin states in single cells), and an integrated reference of 9 molecular modalities in human PBMC: https://t.co/2ypttjJDRt
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We are really excited to share our work on a new modular RNA delivery technology called SEND, built from endogenous components found in the mammalian genome. @ScienceMagazine
https://t.co/0HRvKkDAFV
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Our new work in collaboration with @Satpathology BCL6-dependent TCF-1+ progenitor cells maintain effector and helper CD4 T cell responses to persistent antigen
biorxiv.org
Shortly after priming, the fate of activated CD4 T cells is segregated into BCL6+ follicular helper T (Tfh) and BCL6− effector (Teff) cells. However, it remains unknown how these subsets are sustai...
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We are graduating people from the Kim Lab at a rapid pace. Graduate students and postdocs who are interested in joining us please DM or email me #neuroimmune #mastcell #basophil #ILC #sensation #skin #lung #gut #cytokine @WUSTLImmuno @WUSTLmed @WUSTL @WUSTLdbbs @WUSTLImmuno
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First Edition in @BloodJournal @ASH_hematology Unexpected suppression of tumorigenesis by c-MYC via TFAP4-dependent restriction of stemness in B lymphocytes By @ElenaTonc et al. https://t.co/FOYGecsW6t The oncogene c-MYC engages a tumor suppressive program in B lymphocytes. (1/n)
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Congrats to @WUSTLdbbs's own @jonykipnis, Dr. Marco Colonna, Dr. Simone Brioschi, @WeiLeWang1, @TheVincentPeng, @JSRustenhoven, and @tmamuladze on 2 new mouse studies in @ScienceMagazine revealing the skull as unexpected source of brain immunity. Well done! 1/2
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We are also excited to share a new study from our group that examines the role of CXCR5-dependent cell positioning in LTi-like cell-mediated intestinal immunity. #mucosalimmunology #ILC3
https://t.co/l8QsuRqZG8
pnas.org
Lymphoid tissue inducer (LTi)-like cells are tissue resident innate lymphocytes that rapidly secrete cytokines that promote gut epithelial integrit...
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Thrilled to share our new paper out in @Science on the origins of meningeal B cells in the brain! 🧠 https://t.co/4mBsintogs
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