Kenneth Murphy
@Kenneth90475424
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Joined June 2020
@CalebLareau @BenceDaniel2 @InflammatoryDC @Satpathology Chatted with @Kenneth90475424 about an old paper by Kelsoe on TCR somatic hypermutation. Maybe he is right. Maybe not the same clone went through every single recall response. Also don’t know how many cells are mobilized to each recall response?
pubmed.ncbi.nlm.nih.gov
Somatic hypermutation and affinity-driven selection of active immunoglobulin genes occur in germinal centres (GCs), resulting in the generation of high-affinity memory B cells. In contrast, T...
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