Shiekhattar Lab
@ShiekhattarLab
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@SylvesterCancer @Univmiami
Miami, FL
Joined March 2018
Ramin Shiekhattar receives prestigious @NIHDirector 's Pioneer Award
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Honored to contribute to this work with @DrSDNimer. #TAF1 #Hematopoiesis @Dev_Cell @SylvesterCancer.
🔬 Science meets leadership. As director of Sylvester, @DrSDNimer leads a powerful network of researchers, physicians and patients while continuing his own work in the lab. In his latest study, Dr. Nimer and colleagues uncovered how a key molecule, TAF1, regulates hematopoiesis.
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We also uncover a key role for INTS11 in neurodevelopmental gene regulation.
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We introduce rPRO-seq, a rapid and low-input method to map nascent RNA with nucleotide precision — in just 12 hours and from as few as 5,000 cells. . #RNA #Genomics #PROseq #NascentTranscription #Neurodevelopment #MolecularCell.
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RT @biorxiv_molbio: Tetrameric INTS6-SOSS1 complex facilitates DNA:RNA hybrid autoregulation at double-strand breaks .
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Explore emerging #CancerEpigenetics #CancerTherapy #Epigenomics research with field leaders @KeystoneSymp Epigenetic Mechanisms and Cancer Treatment, this February in Santa Fe! #KSCancerEpi24
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Hello, check our new paper in BioRxiv. It describes new integrator module (INTS9/INTS11 and BRAT1) regulating the neurodevelopment program.
BRAT1 associates with INTS11/INTS9 heterodimer to regulate key neurodevelopmental genes #bioRxiv.
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RT @GardiniLab: Join us for a FUSION Conference on "Genome Regulation through RNA" next February (11-14) in Cancun!..
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RT @GardiniLab: What can machine learning do for your favorite protein complex? A lot! Especially if paired with proteomics and genomics. I….
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RT @FBeckedorff: Interestingly they show H3K4me3 is required to recruit integrator complex, which is essential for the eviction of paused R….
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RT @biorxivpreprint: Human Integrator provides a quality checkpoint during elongation to facilitate RNA polymerase II processivity https:/….
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Our new paper is out on @ScienceAdvances The Integrator complex regulates microRNA abundance through RISC loading .Well done @kirstein_nina and @SaDo47654137 and all collaborators.
science.org
Integrator complex loss resulted in a global miRNA decrease due to defective Integrator-dependent Argonaute protein loading.
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RT @DrChuanChen: #MiamiEpigenetics22 Great opportunities for learning and connecting. Many thanks to the organizers @SylvesterCancer and th….
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RT @SylvesterCancer: We had a great turnout this weekend at the 5th Biennial Miami Epigenetics and #Cancer Symposium with engaging talks fr….
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RT @DrSDNimer: Thrilled that so many experts came to @SylvesterCancer symposium to discuss their most promising and recent research finding….
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RT @NimerLab: Impactful symposium in Miami this weekend! Some of our very own @ShiekhattarLab, @lluismorey, @thecimminolab and @TaylorJ_MD….
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REGISTER NOW! You do not want to miss it!!🧬.
Join us for the 5th Biennial Epigenetics and Cancer Symposium November 12-13 in #Miami! This year’s meeting will include engaging talks from world-renowned scientists discussing the latest research advances in #epigenetics & #cancer. Register Today:
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RT @NimerLab: Governor Desantis announced approval of a $100 million for cancer care and research at @SylvesterCancer and other cancer inst….
news.miami.edu
The Florida funding will help Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine conduct cutting-edge research and improve the care and treatment of patients.
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RT @AznarLab: It’s finally out!! We’re very excited to share our work with all of you!!🥳.
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