Asifa Akhtar
@AsifaAkhtar1
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Vice President, Max Planck Society Director, Max Planck Institute of Immunobiology and Epigenetics
Freiburg im Breisgau, Germany
Joined June 2019
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Its a great honour to be the first international female Vice President of the Max Planck Society. Its an exciting opportunity to contribute towards shaping the future of the Society.
- New team, new ideas
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Ever wondered how the male X chromosome traps the dosage compensation complex for transcription upregulation? Mystery revealed: a new biochemical property of roX2
#RNA
and MSL2 forming a gel.
#Epigenetics
meets
#PhaseSeparation
in our latest story
@nature
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Ever considered that the loss of your favorite epigenetic factor might impact gene expression in an allele-specific manner? Our new study shows allele-specific gene regulation by the chromatin regulator MSL2.
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Its a great honour to receive this award! I am grateful to my team for their outstanding work that enable our lab to get this recognition!
Max Planck Institute of Immunobiology and Epigenetics - Asifa Akhtar receives 2022 Christa Šerić-Geiger Award
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Histone H4 lysine 16 acetylation continues to surprise us. Do you want to know how mothers instruct their kids' gene expression? Check out our latest work. Great collaboration with
@Iovino_Lab
and
@leonidmirny
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Check it out! PTMs provide a powerful means to fine-tune protein function, enabling cells to control processes such as metabolism and cellular memory. Protein acetylation is widespread yet we understand only the tip of the iceberg in many cases!
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Ever wondered why low levels of MOF keep mice slim and whether this is a good thing? A beautiful interplay of epigenetics and metabolism!
Histone H4 lysine 16 acetylation controls central carbon metabolism and diet-induced obesity in mice
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It’s a great honor to be appointed Honorary Professor at University of Freiburg! I am very much looking forward to close and fruitful interactions between the Freiburg University and the Max Planck Institute!
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Want to know more about hematopoiesis, Epigenetics and chromatin? Then read our latest review!
Epigenetic Regulators as the Gatekeepers of Hematopoiesis
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Nuclear envelope provides a fantastic interface for gene regulation. If you want to know more about its role in
@chromatin
organisation,
@phaseseparation
and
@epigeneticregulation
, then read our review
@NatureCellBio
.Functional mechanisms and abnormalities of the nuclear lamina.
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Hematopoiesis is indeed a great system to study the contribution of epigenetic regulators in cell fate decisions!
Check out our latest story about MOF in Science Advances.
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Did you ever wonder whether there was a link between MOF acetyltransferase and the mitochondrial electron transport chain Complex IV? Have a look at our latest story characterising MOF’s new substrate Cox17
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First of all, a very happy new year 2020! My lab is looking for postdoctoral fellows to work on new and exciting projects. Max Planck Institute provides an ideal working environment for developing future carreers. Please forward to interested candidates.
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Check out our latest story linking the epigenetic regulatory NSL complex with ciliary genes and its importance in both ciliated and non-ciliated cells. Interesting implications for ciliopathies and kidney diseases...
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Happy international Women's day. Every female career we can nurture is a great step forward for future generations!
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My lab is currently looking for a bioinformatician to analyse our new and exciting data in epigenomics and transcriptomics. Max Planck Institute in Freiburg is an outstanding environment for ambitious and creative minds to explore their true potential. Please spread the word.
One of the
@mpi_ie
directors is recruiting a bioinformatician. If you're interested in epigenetics and working together with the great
@sun_yidan
then I encourage you to apply.
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X chromosome as an interesting anology for addressing gender gap! English version will be available soon!
Super interesting Friday-Afternoon-Reading in the current issue of the MaxPlanckResearch Magazine. ☕️ Long article on our director
@AsifaAkhtar1
& her research. Online: – Print version for free: – English translation available soon.
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Indeed, we are recruiting! Max Planck institute in Freiburg is an exciting place to start a career in science!
Want to do your
#PhD
in one of the best cities to travel to (and live in 😉) in Europe? (Top 🥉 worldwide, according to
@lonelyplanet
) Then hurry up & join our IMPRS-IEM program in
#Freiburg
. Deadline is approaching soon:
#PhDGermany
#maxplanck
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Check out this very nice new story from the amazing Cecilia from my lab exploring the role of H4K16ac and hematopoeisis..
Have you ever feel like you don fit in a group? Maybe you are at a different state.
I'm pleased to report our recent publication exploring the role H4K16ac in regulating HSCs fate.
@ScienceAdvances
Thanks again
@AsifaAkhtar1
for this great opportunity
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Checkout our latest study. By assembling the genomes of D. Busckii and D. Virils using HiC and comparing with the D. melanogaster we observed that despite extensive rearrangements, interactions between X X chromosomal high affinity sites was conserved!
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Checkout our new story linking the NSL complex with piRNA production from telomeric clusters in flies.
The NSL complex is required for piRNA production from telomeric clusters
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Another great morning meeting with lab members doing home office and welcoming new members to the lab via zoom. Keep up your motivation and above all stay healthy!
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It was really a fantastic event! Great science and discussion! I left feeling very proud to have such wonderful cohort of students within the Max Planck Society! I look forward to seeing your progress in the coming years 😊😊
Inspiring talks & workshops, a thought-provoking debate, nice food, some karaoke and lots of laughter. Yesterday's Max Planck Schools Day 2022 in Berlin was simply amazing! We enjoyed learning more about the research of the other Max Planck Schools
@MPS_cog
and
@MPS_Photonics
🙌
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Thank you!!
Many congratulations to our colleague Asifa Akhtar for receiving the Leibniz Prize 2021!
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Thank you so much for the great hospitality! It was a fantastic day discussing exciting science at CNIO!
Today’s
#distinguished
seminar: “X chromosome: A paradigm to study epigenetic regulation” with
@AsifaAkhtar1
from
@mpi_ie
Welcome to CNIO!
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What a great way to start the Morning with a zoom call with lab members doing home office. Everyone is happy and healthy, and finding interesting ways to progress their projects! Well done.
Are you breaking the
#SocialDistancing
? Only virtually, of course! Bravo
@AsifaAkhtar1
for hosting our weekly lab meeting online! I was very happy to see my peers doing fine and
#workinghard
from home ;)
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It will be a fantastic meeting. Join us and enjoy the science!
Registration & abstract submission open for the next
@EMBLEvents
#Conference
on “
#Chromatin
and
#Epigenetics
”. Fantastic line up of confirmed speakers & more to come from the selected talks. Submit abstracts today!📩➡️
@AsifaAkhtar1
@CKadoch
@GAlmouzni
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Check out this new method from my lab for sorting cell types from developing brain!
Really excited to have our newest paper online. We identify how different cell types communicate with each other during brain development. Great work
@guha_sukanya
@AsifaAkhtar1
@kat_sikora
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Looking forward to attending this meeting and listening about exciting science!
Tomorrow is the kick-off for the
@EMBO
&
@embl
symposium “Metabolism Meets Epigenetics” co-organized by
@mpi_ie
Director Erika Pearce. Exciting line-up of speakers (e.g.
@berger_lab
,
@HaigisLab
,
@AsifaAkhtar1
), have a look at the program:
#EESMetabolism
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A nice new paper from my lab identifying RNA binding domains in proteins in Drosophila and mammals. Check it out!
CAPRI enables comparison of evolutionarily conserved RNA interacting regions
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Thank you Saba for the nice discussion!
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Indeed, it was a very nice meeting! I look forward to future discussions!
Excellent video conference with
@AsifaAkhtar1
@maxplanckpress
@LifeAtLUMS
@Official_NUST
@HECPakistan
to explore research opportunities between
#Germany
&
#Pakistan
. concrete proposals soon.
@SMQureshiPTI
@ForeignOfficePk
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I am so sorry to hear this sad news! Paolo was a great scientist with a fantastic sense of humor! He will be greatly missed. My sincere condolences.
Celebrating the extraordinary life of my dear friend Paolo Sassone-Corsi
@sassonecorsilab
He was an extraordinary talent and will be missed! Paolo had a brilliant mind & boundless energy/enthusiasm for research into circadian biology. A great mentor to many in the field.
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Check out:
This study also suggests that there is some hidden logic behind X chromosomal 3D architecture driving specificity which we still do not fully understand!
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I baked it with my son! It was delicious! Thanks Raed for the great recipe 😊
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Denise was a superb scientist. A big loss for the Epigenetics community!
On today's International Day of Women and Girls in Science we remember the IMP's first female group leader, Denise Barlow, who started her lab in 1988 - and made science history. Read her inspiring story:
#WomenInScience
#WomenInSTEM
@WomenScienceDay
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MAPCap allows high-resolution detection and differential expression analysis of transcription start sites
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Thank you so much for hosting us! It was a fantastic visit and it was great to hear about the fascinating research on criminology 😊
In the neighborhood - today we welcomed Freiburg’s
@AsifaAkhtar1
, vice president of the Max Planck Society and director at the
@mpi_ie
, to our institute. We chatted about
#law
and the
#VR
approach taken by our criminologists.
@maxplanckpress
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MAPCap and CAPRI are two new methods from my lab to accurately map transcription start sites and to map RNA-protein interactions respectively. Check it out!
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Great comment!
As a leader, it can be tough to admit your failures. But, most of us don’t actually want to be led by someone who never fails.
We know we will all face failure at some point, and we want to be led by someone who can be a mentor and role model for how to overcome challenges.
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It was indeed a great afternoon with exciting science! Thanks for the invitation Matthias!!
That was a freakin'blast, today!
Thanks again to all the speakers of the
@activemotif
's 1st CCCG!
@AsifaAkhtar1
@KarstenRippe
@AkisPapantonis
@EddaGSchulz
& Kyung-Min Noh
@EMBLHeidelberg
NEXT Campus Germany at June 2nd!
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This is a fantastic new story from my lab which provides a novel angle to study MOF and the NSL complex! Check it out! And enjoy the movies of the dramatic nuclei!!
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Fantastic group leader retreat with great science!!
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Sorry, here is the correct link! This should be working! Also check out the News and Views from Jerry Workman!
This is a fantastic new story from my lab which provides a novel angle to study MOF and the NSL complex! Check it out! And enjoy the movies of the dramatic nuclei!!
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Welcome Lindsey! Looking forward to working with you in future. How to maintain a creative and productive environment for the next generation of researchers is one of the most important tasks ahead of us!
We would like to introduce
@LindseyBultema
, our new PhDnet Spokesperson. She is looking forward to another year with the steering group. She hopes to strengthen the dialogue with the general admin. & improve the experience of early career researchers within the
@maxplanckpress
.
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My lab is looking for motivated and creative postdocs in the areas of bioinformatics and mouse biology to join us! For more information please go to the our institutes website:
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It is a fantastic meeting! Keep up the good work you are doing!
We're almost midway through the first day of the General Meeting. We want to thank our speakers so far: Prof. Dr. Stratmann (President of the
@maxplanckpress
),
@AsifaAkhtar1
(BMS-VP), Dr. Druschel (CPT-SH), Dr. Mussachio (BM-SH), Dr. Becker (HS-SH)!
#PhDnetGM2020
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I am also looking forward to working together with you!
Congratulations to Asifa Akhtar
@AsifaAkhtar1
, Ulman Lindenberger and Klaus Blaum!
We are truely looking forward to working together to ensure better support for juniour scientists!!
@maxplanckphdnet
@maxplanckpress
👩💻👨🔬☀️🥳
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What a great comment!
If you work in research, you’ve probably never met another researcher who doesn’t fear failure or feel the sting of rejection. You’ve just met a lot of people who prefer not to talk about it. Vocalizing our fears and struggles is a powerful first step toward overcoming them.
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This will be a great event with fantastic science and inspiration for the next generation of scientists!
Our GRS meeting fits really nicely with the associated GRC
@GordonConf
organized by
@AsifaAkhtar1
and vice chair Geeta Narlikar
“Chromatin Modifications, RNA and Metabolism” (May 31 - June 5, 2020)
For more info on the GRC:
/4
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@RockefellerUniv
This is extremely sad news! Dave was a true pioneer and one of the giants of chromatin and epigenetics field! He will be deeply missed!
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Many congratulations Caroline!
Dame Caroline Dean
@CarolineDeanLab
@JohnInnesCentre
to receive the Wolf Prize in Agriculture for her groundbreaking work on epigenetic memory. Congratulations, Caroline!
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This was really fantastic two days with the lab! I am so proud of all of you!
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Great upcoming opportunities to work the Max Planck Institute. Watch out!
New year 🥳! New job 🧪🧬? Many labs at the
@mpi_ie
in
#Freiburg
are looking for Technical Assistants supporting research in
#immunobiology
and
#epigenetics
– including the labs of
@AsifaAkhtar1
, Thomas Boehm & our DeepSeq facility. Get the details here:
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Well done Vivek! Proud of you!
Very happy to receive the
@EMBO
-LTF! Thanks to the review committee and to my current and former supervisors for their support. 🙂
@_Hubrecht
@mpi_ie
@AsifaAkhtar1
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Great initiative!
Do you feel socially isolated, overwhelmed by work or both? Are you curious about what are we up to? 🤨
Join our Collective TeaTime this Friday, 22nd, at 3pm to share good vibes, slow down busy minds & simply connect. 💚
See you there!
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Thank you Christophe for this very nice Spotlight review of our study diving into the role of MOF in hematopoiesis!
The very nice work by
@cica_dups
&
@AsifaAkhtar1
published recently in
@ScienceAdvances
inspired
@YNSerinaS
and I to write a mini review on the role of MOF in Hematopoiesis.
#epigenetics
#chromatin
#hematopoiesis
@mpi_ie
@embl
@TrendsGenetics
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I am looking forward to my visit and interacting with the students!
@genopolys
@CNRS_OccitaniE
@umontpellier
@IsiteMUSE
12 NOV 2019 - 14h
@genopolys
Asifa AKHTAR
@AsifaAkhtar1
, Max Planck Institute of Immunobiology and Epigenetics
@mpi_ie
- Freiburg, Germany
Title: Dosage compensation of the X chromosome: An intricate epigenetic phenomenon involving chromatin regulators and long non-coding RNAs
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Thank you my dear brother Ali
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I am deeply saddened by this news!! She was an amazing role model for women!! Many condolences!!
A devastating loss. Everybody loved her. For her brilliance, honesty, bluntness, loyalty and zest for life. And she was funny. So very funny. Rest In Peace dear dear friend. Deepest condolences to her family and the
@MIT
community.
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Indeed! Timing is flying 😀
Fantastic to see
@AsifaAkhtar1
appointed Vice President of
@maxplanckpress
- a great choice
Only seems like yesterday we were PhD students in adjacent labs….
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Thank you very much!
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@IbrahimCisse_
Absolutely fantastic news Ibrahim! I am happy and proud to have you as a colleague at the Max Planck institute in Freiburg. Well done!
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@EMBLEvents
@maxplanckpress
@GAlmouzni
@institut_curie
I am looking forward to this great event starting from tomorrow! It promises to be full of scientific highlights with a great lineup of speakers! Join us and enjoy the science!!
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Thank you so much Oded!!
“Thus, maternal H4K16ac provides an instructive function to the offspring, priming future gene activation.” a very important finding from
@AsifaAkhtar1
!
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You have been a great inspiration! Thank you!
Yesterday was the last day of Angela Friederici’s term (2014-2020) as Vice-President of
@maxplanckpress
. As VP, in addition to directing
@FriedericiLab
(
@MPI_CBS
), she promoted important issues, e.g., the advancement of women. We are grateful for her commitment in this dual role!
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@McKnightLab_UO
I admire your courage and your amazingly positive attitude in these extremely difficult times! You have my deep respect.
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Thank you Prashant!
This morning
@AsifaAkhtar1
talked at
#MedicalEpigenetics
lecture series abt dosage compensation as model system to not only study gene regulation & epigenetics,bt also how it has huge implications in basic research & therapeutics. Great science and discoveries. Wonderful morning.
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@embl
@EMBLEvents
@GAlmouzni
@CKadoch
@Iovino_Lab
It was a perfect first day with exciting talks! Looking forward to day 2!! Join us!!
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Thank you Oded!!!
Beautiful! The condensing nature of roX–MSL2 CTD is what determines the specific compartmentalization of the X chromosome (in Drosophila).
@nature
🔥
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Thank you!
@maxplanckpress
Finally a woman AND the third fly person as Vice President of the
@maxplanckpress
society biomedical section. All the very best
@AsifaAkhtar1
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Enjoy reading!!
Congratulations
@Adamu56106323
Really wonderful story. And also Congratulations to all the authors of the story specially
@AsifaAkhtar1
:)
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Many congratulations Claire! This is great news!
#TalentsCNRS
Nous célébrons cet après-midi nos 2 Médailles d'Argent, Claire Mathieu, chercheuse en
#informatique
à l'
@IRIF_Paris
, et Claire Rougeulle, chercheuse en
#biologie
à
#parisepigenetics
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You have done a tremendous job as the Vice President! Thank you for all your efforts in bringing the Society forward!
Last talk as VP in front of the section. Split feelings. Relief and withdrawal 😅. But always great to be member of such an amazing organisation
@maxplanckpress
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Thank you!
Congratulations
@AsifaAkhtar1
. There is so much to learn from your successful journey. From leading an excellent research program to lead one of the best institutes & now being VP Max Plank Society. Truly an honor, encouraging for girls in science here in Pakistan in particular.
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Thank you Igor!
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Thank you Giulio!
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Thank you Axel!!
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Thank you Nina!
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Join us! It will be a great scientific event enjoying the latest on
#chromatin
and
#epigentics
and much More ....
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Thank you Danny!
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Thank you Shiv!!
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