Sinan Shi
@ShiSinan
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RT @fuopen: Excited to see my project at @UniofOxford finally published at @NatureGenet ! Huge thanks to my co-authors @simon_r_myers @dan….
nature.com
Nature Genetics - This study introduces the concept of Ancestry Components and shows that they can offer improved population stratification correction for geographically correlated traits. By using...
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RT @leo_speidel: Happy New Year!.Our Twigstats paper is now out!.
nature.com
Nature - Twigstats, a method for ancestry reconstruction, provides high-resolution genetic histories and movement patterns of people living in Europe during the first millennium ce.
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RT @biorxiv_genetic: Fast variance component analysis using large-scale ancestral recombination graphs #biorxiv_ge….
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RT @robbie_stats: On behalf of @zilongli21 , @A_Albrechtsen and myself, I’m pleased to announce the release of QUILT2, a method for lc-WGS….
biorxiv.org
Inexpensive and accurate genotyping methods are essential to modern genomics and health risk prediction. Here we introduce QUILT2, a scalable method for genotype imputation using low-coverage...
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Many thanks to all the collaborators, and especially to @simon_r_myers and @marchini who led this project!.
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Our paper on the GEL haplotype reference panel and the latest whole-genome imputed #ukbiobank data (21008) is out #NatureGenetics, implying rare non-coding mutations are not as disruptive as coding variants.
nature.com
Nature Genetics - A Genomics England haplotype reference panel constructed using sequence data from 78,195 individuals improves phasing and imputation accuracy. Imputation of the UK Biobank using...
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RT @marchini: @privefl @anderson_carl @alyssa_clay @LeGuenYann @josep_mercader @uk_biobank @FachalLaura Imputation from the Genomics Englan….
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Very interesting new method describing genealogy-based association that detects more rare and ultra-rare signals than imputation.
Excited to share our bioRxiv preprint on genealogical inference and genealogy-based mixed model analysis in the UK Biobank! For a summary of this work, see our ASHG 2021 talk (session 017). Joint work with @aabiddanda and Pier Palamara.
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RT @leo_speidel: This is one you can share with your budding scientists! Hope to see a surge in population geneticists in a few years. Gr….
kids.frontiersin.org
Almost every cell in our bodies contains DNA. DNA is a molecule that stores the instructions for how our bodies work and it is passed on from parents to their children. In this article, we show you...
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RT @OxfordStats: Pier Palamara's research group at @OxfordStats and @HumanGeneticsOx is recruiting two ERC/NIH-funded postdoctoral research….
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RT @biorxivpreprint: A high-resolution map of non-crossover events in mice reveals impacts of genetic diversity on meiotic recombination h….
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RT @marchini: The UK Biobank genetic data paper is published today in Nature @uk_biobank @nature @bycgen.
nature.com
Nature - Deep phenotype and genome-wide genetic data from 500,000 individuals from the UK Biobank, describing population structure and relatedness in the cohort, and imputation to increase the...
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