RT @GoogleDeepMind: Introducing AlphaGenome: an AI model to help scientists better understand our DNA – the instruction manual for life 🧬….

Today the predictions from AlphaMissense (@GoogleDeepMind) have been integrated into @ensembl, @uniprot & the AlphaFold database. An important step in making predictions from machine-learning tools accessible to a wide audience. Great work @emblebi !

RT @jun90cheng: We have received lots of interest in AlphaMissense, the @GoogleDeepmind model predicting the probability of a missense vari….

Ever wondered what chatGPT's brain looks like? My brother made a very cool 3D visualisation and interactive tutorial dissecting the inner workings of a (small) large language model. Check it out!.

RT @MariaC_Su: I'll be speaking at the @rhodestrust #TechandSociety2023 forum, as part of the *Pathways to Responsible Technology: Applied….

Super excited to be at #ASHG23 with fellow DeepMinders @Avsecz and @jun90cheng. Curious about variant effect prediction models AlphaMissense and/or Enformer?Come chat! We can be spotted during poster sessions roughly around this coffee station.

RT @caina89: Less than a week to #wcpg2023, looking forward to seeing everyone there! . My lab is hiring postdocs to work on quantgen metho….

Was a delight to present AlphaMissense at @CAGInews. Thanks very much to the organisers for an excellent conference! I learned a ton, and enjoyed all the lively discussions. May more of us 'catch CAGI' !.

RT @nickywhiffin: This is a fantastic program that has had some superstars of human genetics pass through it. A chance to work with some in….

Oh, and don't forget digging into the 60K different protein isoforms! Such a privilege to work with the brilliant @avsec, @juncheng, @joshbiology + others. Looking forward to seeing the creative ways others use this resource.

. prioritising variants for mutational scanning assays to precisely map the effect of variation on protein function. .

. predicting functionally-important genes that are short, so harder to identify using cohort-based methods. .

🧵So what could these predictions be used for? A few ideas: narrowing the search-space of potential disease-causing variants for diagnosing patients with rare disease. .

Ever wondered which of those pesky missense mutations were likely to be pathogenic and which ones benign? Enter AlphaMissense! It’s not just a fancy AI model - it has real implications for human genetics. Juicy details now in Science

RT @emblebi: The new AlphaMissense catalogue from @GoogleDeepMind can be used with the @ensembl Variant Effect Predictor to predict variant….

RT @Avsecz: We started the project by wondering how we could leverage the AlphaFold model (not just its predicted structures), for the path….

RT @caina89: My lab @PioneerCampus is hiring! . We are looking for a postdoc interested in working on #singlecell and #spatial data to unra….

Really cool example of adapting DNA sequencing technology to be made more mobile and much cheaper, so can be used in many more contexts

So true! I can highly recommend trying to explain your science to 10yr-olds - harder than it looks, and a great way to improve your communication of science to anyone

RT @OlinkProteomics: On Friday, we got the first delivery of samples from #UKBiobank. The delivery box contains 1470 samples. In a very sho….