Very excited to seeing this published @CellReports TIGER: The gene expression regulatory variation landscape of human pancreatic islets

I will stop using this app, which I’ve been embarrassingly using for too long. I will use only @josepmercader.bsky.social from now on

Good to see 👍

It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS, indeterminate dendritic cell histiocytosis

📽️🍿🧬 Check out @Yunfeng_Ruan's talk in our growing collection of videos on the @PRSdiversity website:

📣The recording of "Polygenic risk scores: method development and application" by @Yunfeng_Ruan is now available: https://t.co/fqMlhd87d2…. This talk is part of @broadinstitute 's MPG Primer series. For more info, check out https://t.co/h21I2Km019

In my diversity supplement-funded graduate research, I used different types of mice to find DNA regions that alter susceptibility to air pollution. One of these regions is also found in humans and likely influences how people with lung diseases are affected by breathing pollution

Beautiful paper and thread! Congratulations!

We’re hiring soon! 1–2 MSc positions, one PhD position (all fully funded), and a post-doc position will be available. Stay tuned and join us at McGill in the vibrant city of Montreal, Canada! Lab webpage: https://t.co/WfX5JOYTh9

Excited to share the paper: Huntington's disease is a DNA process for almost all of a cell's life. Inherited HD alleles are innocuous, just unstable – CAG repeats slowy expand throughout life. We call it a "ticking DNA clock".

New preprint on proteomics data from GTEx. 10,841 proteins measured in 700 samples (from 5 tissues) using mass spec. Fang, Jiang et al. medRxiv https://t.co/HQuggPy6Yt

1. landing 'base' for knowledge on the human pancreas 2. harmonized donor meta-data spanning several sources in 1 place. 3. integrated single-cell browser 4. knowledge graph for eQTL results 5. complete access at all levels of data/results

🎆 Ring in the new year by reviewing the PRIMED Consortium's progress on improving genetic risk prediction in diverse genetic ancestry populations. See our Research Highlights https://t.co/76z2JK9lyw and video collection https://t.co/w1o2NhZ3uI

It was great to be able to contribute the EP400 finding to this paper together with @Gianina_Natoli and @ChiaraFolland , flagging a novel CAG repeat locus in the EP400 gene as a likely (though extremely rare) cause of spinocerebellar ataxia when expanded beyond 55 repeats.

📊eQTL summ stats: https://t.co/M4fRwwbWHN 📜paper: https://t.co/0ZuqdNxnn4 📰early-version preprint: https://t.co/lby1uM4X58 🌐interactive browser of colocalized signals: https://t.co/GdiCIMI3Qm

A major eQTL resource for cardiometabolic research🧬 👉eQTL meta-analysis of subcutaneous adipose tissue samples in N=2,344 👉eQTLs detected for 18,476 genes (34,774 signals)❗️ 👉3,595 colocalized signals with cardiometabolic traits 🔗links to data and paper👇

Our mentor Casey Brown, apart from being an extraordinary scientist, was a brilliant teacher who loved everything genetics. In his honor, some of the world's leading experts came together to create the 'Casey Brown Lecture Series' on human genetics 1/

@marcotrizzino @tuuliel @STRUANGRANT @alexisjbattle

Per si de cas:

Starting off the new year with a new paper! 🎆📰 Check out @mauer_jh 's fantastic manuscript evaluating features influencing the accuracy of local ancestry inference in admixed populations. Tweetorial posted previously for the preprint below, and PDF at:

Delighted to have collaborated with the @guy_rutter lab in this study linking long non coding RNA to epigenetic regulation in beta cells. 👌💯💪 https://t.co/4gtrUAgSaN