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Mu Yang, Ph.D. Profile
Mu Yang, Ph.D.

@mumumouse2

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Behavioral neuroscientist. Scientific integrity matters.

New York
Joined November 2023
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@mumumouse2
Mu Yang, Ph.D.
13 days
I caused an entire BOOK to be retracted. Reported 6 months ago. Swift decision by @SpringerNature . Also reported several books by the same authors to @ElsevierConnect , did heard a beep.
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@mumumouse2
Mu Yang, Ph.D.
11 days
Editor: You didn't stop for a second and think "honey is amazing for Alzheimer's?!". ....Anyway, lots of back and forth between the authors and sleuths here
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@mumumouse2
Mu Yang, Ph.D.
2 months
I matched a neuroscience PI at Harvard yesterday, on a dating app. Of course I immediately said I am one of those sleuths. Of course he immediately unmatched me. I laughed so hard. Empowering doesn't come close to describe it.
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@mumumouse2
Mu Yang, Ph.D.
9 days
To friends who followed me from India and Iran this week, thank you for your support. My home country (China) is also plagued with fraudulent publications, and I share your frustration. The cause of the issue is very complicated, but together, we can start to make changes. 🙏
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Mu Yang, Ph.D.
18 days
Weekend conversation on integrity: We need to address "toxic pressure in the lab" in order reduce fraud. Many cases of fraud were probably the result of desperate people working under duress. Implicit messages from PIs on what results are desirable are very harmful. Your turn.
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@mumumouse2
Mu Yang, Ph.D.
13 days
If you are interested in the evidence, here it is. @ImageTwinAI did most of the work!
@mumumouse2
Mu Yang, Ph.D.
13 days
I caused an entire BOOK to be retracted. Reported 6 months ago. Swift decision by @SpringerNature . Also reported several books by the same authors to @ElsevierConnect , did heard a beep.
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@mumumouse2
Mu Yang, Ph.D.
10 days
This is not about a specific country. China (where I came from) has its huge share of F papers. Ultimately, the editors and publishers are the gatekeepers. The responsibility is not negotiable, given profits are involved. Let's keep the conversation civil.
@mumumouse2
Mu Yang, Ph.D.
11 days
Editor: You didn't stop for a second and think "honey is amazing for Alzheimer's?!". ....Anyway, lots of back and forth between the authors and sleuths here
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@mumumouse2
Mu Yang, Ph.D.
7 days
After a behavioral experiment today (my actual job), I held a mouse in my hand and thought about the number of compromised studies that used mice, and how many little lives were lived for nothing, I choked up. Team🐭🐁
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@mumumouse2
Mu Yang, Ph.D.
10 days
@DavidAotearoa That's my point! Editor(s) and at least two reviewers were apparently okay with it.
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@mumumouse2
Mu Yang, Ph.D.
6 days
Elsevier notified me about a "batch retraction" of 7 papers from Journal of Chemical Neuroanatomy.
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@mumumouse2
Mu Yang, Ph.D.
8 days
This is what the BEST sleuth gets in return for her relentless fight against fraud? More need to join her and I am one.
@MicrobiomDigest
Elisabeth Bik
9 days
@ProfRobHoward Not from Lindsay so far, but I got a couple of others in the past (all from Cassava fans).
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@mumumouse2
Mu Yang, Ph.D.
13 days
@lonnibesancon @SpringerNature @ElsevierConnect I am waiting to get my hate mails. You can't have them all 😅
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@mumumouse2
Mu Yang, Ph.D.
4 months
Four years is how long ago I started reporting this case. Thanks to the sleuth community that came together ( @MicrobiomDigest @Thatsregrettab1 and many others), we are no longer silent. Thank you @TomAvril1 at @PhillyInquirer for the reporting.
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@mumumouse2
Mu Yang, Ph.D.
12 days
@Benonisim Correct. There are multiple other books similar to this, most published by Elsevier.
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@mumumouse2
Mu Yang, Ph.D.
1 month
Send papers/cases this way. I'm bored.
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@mumumouse2
Mu Yang, Ph.D.
10 days
@SilentDraggon I worry more about the publisher (Elsevier, again, and again) not being able to catch this sort of stuff.
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@mumumouse2
Mu Yang, Ph.D.
11 days
My work (on that book retraction) made to the RW Weekend Reads yay!
@RetractionWatch
Retraction Watch
11 days
Weekend reads: Editor under scrutiny resigns; bullshitting scientists; questionable practices in expanding disciplines
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@mumumouse2
Mu Yang, Ph.D.
2 months
One study used rat tissue and the other human tissue. Somehow an image occurred in both.
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@mumumouse2
Mu Yang, Ph.D.
3 months
Let me know if you spotted differences in the graphs.
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@mumumouse2
Mu Yang, Ph.D.
20 days
Scientific Reports is a good training ground for aspiring sleuths. There, I said it.
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@mumumouse2
Mu Yang, Ph.D.
23 days
Never mind AI, I am not sure you even need a science degree to see it (and I didn't mark everything). Nevertheless it is in Eur J. Medicinal Chemistry (2023).
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@mumumouse2
Mu Yang, Ph.D.
8 days
Marking is messy because same images were differently cropped and used multiple times. I didn't mark all, otherwise too messy. Nanjing Univ is one of top 10 universities in China. And this is in the Nature journal with all-Chinese editors.
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@mumumouse2
Mu Yang, Ph.D.
2 months
Arguing about data is extremely hard. But sometimes it is not.
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@mumumouse2
Mu Yang, Ph.D.
4 days
Helping mom indexing hers and my dad's papers. This is one of the papers by the two of them. The greatest love story.
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@mumumouse2
Mu Yang, Ph.D.
2 months
When you are too lazy to report each paper to each EIC, you dump the "monthly collection" to the Integrity team at @ElsevierConnect and hope for miracles.
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Mu Yang, Ph.D.
13 days
@JeanClaudeFox2 @SpringerNature @ElsevierConnect Lots image issues, probably will take a while to write the retraction notice. I might share the dossier on Google drive if anyone is interested.
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@mumumouse2
Mu Yang, Ph.D.
22 days
This sleuth-in-training needs your opinions: 1) What could be the incentives to publish a lot of papers that are rarely cited? 2) Should we worry about such papers?
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Mu Yang, Ph.D.
29 days
I accidentally caused a Retraction "The corresponding author contacted the editorial office with a request to correct Figure 3A. However, image analysis performed by the editorial office revealed the revised Figure 3A still contained image duplication..." PMID 38608700
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@mumumouse2
Mu Yang, Ph.D.
5 months
I contributed about 40. That's quite a percentage for one person me thinks 🙃 More than 10,000 research papers were retracted in 2023 — a new record
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Mu Yang, Ph.D.
2 months
@seanluomdphd Probably doesn't want me to scan his papers lol.
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@mumumouse2
Mu Yang, Ph.D.
16 days
Cited 243 times (Human Molecular Genetics)
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@mumumouse2
Mu Yang, Ph.D.
8 days
Error bars are present, but VERY VERY hard to see. This seems to be a Nature journal that's under an all -Chinese editorial team. Not sure how if there is a mechanism to prevent favoritism. I asked to see raw data on Pubpeer.
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@mumumouse2
Mu Yang, Ph.D.
5 days
I don't mean to troll Journal of Chemical Neuroanatomy (Elsevier), but.
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@mumumouse2
Mu Yang, Ph.D.
1 month
Not very subtle. Detected with bare eyes (of a sleuth who has never done Western blot). Icahn School of Med at Mt. Sinai. pubmed 27143420
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@mumumouse2
Mu Yang, Ph.D.
18 days
Thank you @PLOSONE for performing a proper investigation.
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@mumumouse2
Mu Yang, Ph.D.
4 months
Found this between coffee and going to work.
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@mumumouse2
Mu Yang, Ph.D.
4 months
Hell NO
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@mumumouse2
Mu Yang, Ph.D.
2 months
I communicated with the EIC of J. Chemical Neuroanatomy (Elsevier) many many times about this. He kept promising actions and even asked me what tools I use, and I told him. A random check today on a recent paper indicates a lack of improvement.
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@mumumouse2
Mu Yang, Ph.D.
27 days
Cited 248 times since 2009. pubmed 19460457
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@mumumouse2
Mu Yang, Ph.D.
7 days
Sleuth pointed out the pasted part in A, author volunteered to correct B, incorrectly, saying .... "I am not very skilled at putting these figures together....". Now we just don't know. @lonnibesancon .
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@mumumouse2
Mu Yang, Ph.D.
2 months
Lazy sunday.
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@mumumouse2
Mu Yang, Ph.D.
17 days
The "Survival of the Fittest" mentality is the source of more than a couple of vile things that plagued our culture. Now it is also plaguing the science community. About time to be woke on this one.
@krause_bird
Krause
17 days
@SocialImpurity @mumumouse2 Alternatively, it seems like you are putting the personal responsibility on the people who are being honest and not producing flashy results because of it, while suggesting they don't belong. That attitude is benefitting the fraudsters.
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@mumumouse2
Mu Yang, Ph.D.
13 days
@aj_boston Not in my CV, but I keep track of them
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@mumumouse2
Mu Yang, Ph.D.
2 months
Just as I was about to conclude that Elsevier doesn't do anything about anything, here comes evidence of some effort. Appreciated it! Reported last May.
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@mumumouse2
Mu Yang, Ph.D.
2 months
The black line has several segments that seem to be identical repeats or very similar. See green, yellow, and blue boxes. I most likely missed a lot, but am better than AI on this one haha. pubmed 35759866
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@mumumouse2
Mu Yang, Ph.D.
6 days
Different cells. Probably not good.
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@mumumouse2
Mu Yang, Ph.D.
5 months
I sent about equal numbers of reports (hundreds?) to @SpringerNature and @ElsevierConnect last year. But @SpringerNature retracted A LOT more. 👍
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@mumumouse2
Mu Yang, Ph.D.
1 month
It is shocking that mice can find the platform in a 120cm pool on day 1 in about 10s on average, with two reaching almost immediately. Notwithstanding a visual cue was present. Yes yes their tracking software "blinked" too long, I am sure that's the reason. @VVoikar
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@mumumouse2
Mu Yang, Ph.D.
29 days
How many times is too many times to re-use one's control data without acknowledging it in later papers? Yellow arrows point to data identical in 3 papers.
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@mumumouse2
Mu Yang, Ph.D.
20 days
This email from an Elsevier publisher is a bit perplexing. This is after I raised the concern that an Elsevier journal has many "problematic" papers. They are just implementing AI software, after I have been telling them about the problem for two years? The"Prof" is the new EIC.
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@mumumouse2
Mu Yang, Ph.D.
24 days
Fourth from this group. I can't think of how adjusting for baseline, age, and BMI could lead to identical error bars on all measures between two separate groups.
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@mumumouse2
Mu Yang, Ph.D.
2 months
@Spottingthespot I just remembered seeing those numbers in one paper when I saw them in the second paper.
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@mumumouse2
Mu Yang, Ph.D.
1 month
Not simple overlap. Several aspects were changed. pubmed 27810782
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@mumumouse2
Mu Yang, Ph.D.
15 days
1) Different mouse models, 2) re-use not mentioned, 2) blots were partial in the 2012 (earlier) study, 4) supposed to show 4 lanes in the 2012 study and 8 lanes in the 2015 study?
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@mumumouse2
Mu Yang, Ph.D.
2 months
This goofy stuff has finally been retracted. Well, only took 13 months, not bad. See here for a lot more problems .
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@mumumouse2
Mu Yang, Ph.D.
2 months
Another retraction by @SpringerNature . Appreciated it!
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@mumumouse2
Mu Yang, Ph.D.
2 months
In what way does the "corrected" image make any sense? European Journal of Pharmacology will allow it. pubmed 36870913
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@mumumouse2
Mu Yang, Ph.D.
4 days
*This is a scrutiny/discussion*. This study shows an astonishing effect of 30-day fish oil in repairing axons and drastically reducing APP levels in rats. It seems very very amazing. PMID 20635852 @jsmoliga
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@mumumouse2
Mu Yang, Ph.D.
1 month
There seems to be more than one vertical breaks. pubmed 21820214
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@mumumouse2
Mu Yang, Ph.D.
24 days
Fifth (all in Elsevier journals), and I am mildly paranoid. There are MANY expression of concerns on this group's studies. But not many retractions.
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@mumumouse2
Mu Yang, Ph.D.
3 months
This is fun. Looking for differences instead of similarities. pubmed 29474924
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@mumumouse2
Mu Yang, Ph.D.
21 days
I will always remember this reply when I'm exhausted and blurry eyed from screening papers in the future.
@eryney_ok
eryney marrogi
21 days
@mumumouse2 medicine is actually rife with these types of papers. it makes it extremely difficult to determine what is a real effect/a finding worth considering. at least in bio or other fields you can validate with little consequence, with medicine a bad study can have deadly consequences
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@mumumouse2
Mu Yang, Ph.D.
3 months
@OKalliokoski Advanced level
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@mumumouse2
Mu Yang, Ph.D.
3 months
Sometimes one paper is enough to convince you that there needs to be a "file". This is one of those. In Journal of Neuroscience.
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@mumumouse2
Mu Yang, Ph.D.
1 month
We are still looking at the Mt Sinai paper I mentioned yesterday. pubmed 27143420. pubpeer link here
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@mumumouse2
Mu Yang, Ph.D.
29 days
The p values seem to be a mistake?
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@mumumouse2
Mu Yang, Ph.D.
3 months
Retracted a year after it was flagged. That is pretty fast. @SpringerNature is doing a lot better than Elsevier on this front, in my experience dealing with integrity folks in both.
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@mumumouse2
Mu Yang, Ph.D.
2 months
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@mumumouse2
Mu Yang, Ph.D.
4 months
Why would you use a rat picture to illustrate a mouse experiment?
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@mumumouse2
Mu Yang, Ph.D.
4 months
Tiny error bars triggered a scan. @ImageTwinAI found the same image representing different treatment groups in 2 papers.
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@mumumouse2
Mu Yang, Ph.D.
4 months
SEM seems really tiny for N=4-5. PMID: 31028778
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Mu Yang, Ph.D.
22 days
Differently cropped and brightness adjusted. Might deserve a M word.
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@mumumouse2
Mu Yang, Ph.D.
23 days
I am perfectly happy to believe the same SDs (0.13) in most columns is a mistake, but it's kind of cavalier that the authors didn't bother to reply or anything since I flagged it in January. pubmed: 36899414
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@mumumouse2
Mu Yang, Ph.D.
4 months
1000th on Pubpeer.
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@mumumouse2
Mu Yang, Ph.D.
3 months
Continuing what we started yesterday. This is in J. Neuroscience 2014. PMID24501346.
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@mumumouse2
Mu Yang, Ph.D.
6 months
My account was hacked and suspended 2 weeks ago. X does not seem to have live humans to help, hence this new account. Please add @MicrobiomDigest @schrag_matthew @cpiller @Thatsregrettab1 @jamesheathers @TigerBB8 @PSBROOKES @nickwizzo and many more friends I don't want to lose!
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@mumumouse2
Mu Yang, Ph.D.
5 months
Reported in March. Retracted just now. Decent pace. Thank you @SpringerNature
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@mumumouse2
Mu Yang, Ph.D.
20 days
A certain level of data anomaly needs to be considered as "hard evidence" in the future. If we can only/primarily rely on on image evidence, then what happens when people start to launder their images with AI tools which *will* become more and more available?
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@mumumouse2
Mu Yang, Ph.D.
2 months
AI doesn't do this yet. But we got 👀
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@mumumouse2
Mu Yang, Ph.D.
9 days
@ex7r3me This is a universal strategy ---- throwing students or technicians under the bus
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@mumumouse2
Mu Yang, Ph.D.
2 months
It's 2024 and I know for a fact that @SpringerNature has AI screening tools. PMID: 38170385
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@mumumouse2
Mu Yang, Ph.D.
10 days
@Hazrat_Maziar Thank you for sharing this perspective!
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@mumumouse2
Mu Yang, Ph.D.
1 month
This data anomaly was listed as one of the reasons to RETRACT this paper! @SpringerNature is very progressive in terms of heeding (traditionally ignored) data anomaly evidence!
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@mumumouse2
Mu Yang, Ph.D.
1 month
To be on this team is most incredible learning experience.
@cpiller
Charles Piller
1 month
The stories relied on determined whistleblowers – @schrag_matthew worked for months to examine the work of @USC_ZilkhaNeuro leader Berislav Zlokovic. And Kevin Patrick, @mumumouse2 , @microbiomdigest , @mike_rossner made key contributions/confirmations 2/4
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@mumumouse2
Mu Yang, Ph.D.
3 months
I don't know anything about this🙃
@MicrobiomDigest
Elisabeth Bik
3 months
29 papers from a neurology professor at @RushUniversity @RushMedical have raised concerns on @Pubpeer . Papers involve research on cinnamon to treat brain disorders. Leonid Schneider summarizes the concerns at @4BetterScience
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@mumumouse2
Mu Yang, Ph.D.
27 days
2nd and 3rd month MAS (a clinical scale 0-4) data appear identical. The cerebrolysin group has the same SD in months 1,2,and 3. This was used to shown clinical efficacy of the drug, so maybe a little scrutiny is not too rude. pubmed 38585517
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@mumumouse2
Mu Yang, Ph.D.
1 month
Also me
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@mumumouse2
Mu Yang, Ph.D.
3 months
3 out of 4 groups overlap. The merge images are intriguingly different. Pubmed 26125041
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@mumumouse2
Mu Yang, Ph.D.
1 month
Part 1: The Erratum was published after I pointed out the red circle in A. Supposedly the correct image was made from the Original blots. I can't seem to match most of it. And the retina and PRE blots seem same in the correction.
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@mumumouse2
Mu Yang, Ph.D.
5 months
It's a privilege to learn from the best 🙏🙏🙏
@MicrobiomDigest
Elisabeth Bik
5 months
@mumumouse2 That is quite a lot! There are 8000 that were retracted from Hindawi Special Issues, which were mainly done through its current publisher Wiley, without specific contributions of volunteers, so 40/2000 is a lot. Thank you so much for your contributions. Much appreciated ❤️
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@mumumouse2
Mu Yang, Ph.D.
22 days
That's huge one! 😆😅😂🤣
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@mumumouse2
Mu Yang, Ph.D.
29 days
Saw this tweet on someone's phone in the elevator after work. Oh good God, the days when I'm only known to the Columbia community as the "woman who runs the mouse behavior core" may be numbered.
@mumumouse2
Mu Yang, Ph.D.
29 days
The p values seem to be a mistake?
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@mumumouse2
Mu Yang, Ph.D.
2 months
I agree that mistakes happen and MANY image issues were caused by mistakes. But a good sleuth (that I hope to become someday) differentiates mistakes and non-mistakes. Here is an example.
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@mumumouse2
Mu Yang, Ph.D.
2 months
Hemorrhage data in stroke patients in a clinical trial. Not sure I trust it. pubmed: 20968198
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@mumumouse2
Mu Yang, Ph.D.
4 months
I begged RW to write the case many moons ago. Glad to see this tweet. Thank you!
@RetractionWatch
Retraction Watch
4 months
“Critics claim to find flaws in dozens of Alzheimer’s studies by Temple scientist.”
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@mumumouse2
Mu Yang, Ph.D.
1 month
Since there are more people willing to talk about error bars, let's revisit this PNAS paper (pubmed: 35353605) where I have questions about missing error bars in B and D. N=3.
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