Dylan Ryan
@RyanLab_MBU
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Group leader at MRC mitochondrial biology unit (MBU), University of Cambridge. An immunometabolism enthusiast. 🦋 @ryanlab.bsky.social
University of Cambridge
Joined August 2021
Last few weeks of #immunometabolism discoveries @Bims_BiomedNews ⬇️⬇️⬇️. Highlight:.Caspase-11 drives macrophage hyperinflammation in models of Polg-related mitochondrial disease.
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RT @casanova_lab: Superb paper by Megan Cooper and colleagues !. Mosaic STAT5B gain-of-function associated with demyelinating disease and a….
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RT @LabWaggoner: ICOS regulates IL-10 production in group 2 innate lymphoid cells via cholesterol and cortisol biosynthesis @jclinicalinves….
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RT @Pluchinolab: MitoTracker transfers from astrocytes to neurons independently of mitochondria | bioRxiv
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RT @Chrest_brett: Excellent article by DeBerardinis: "trust your instincts, capitalize on your environment, ask challenging questions, thin….
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RT @AitorJarit: Last Friday I defended my thesis at CNIC and we had a really motivating scientific discussion. Many thanks to the committe….
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Highlights (6/n).Thermal proteome profiling of itaconate interactome in macrophages.
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Highlights (5/n).FABP7 is increased in progressive multiple sclerosis and induces a pro-inflammatory phenotype in monocytes through a glycolytic switch.
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Highlights (4/n).Mitochondrial dysfunction enhances influenza pathogenesis by up-regulating de novo sialic acid biosynthesis.
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Highlights (3/n).Systemic metabolic changes in acute and chronic lymphocytic choriomeningitis virus infection.
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Highlights (2/n).RIPK1 senses S-adenosylmethionine scarcity to drive cell death and inflammation.
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📢Last two weeks of #immunometabolism discoveries @Bims_BiomedNews ⬇️⬇️⬇️. Highlights (1/n).The prostacyclin receptor PTGIR is a NRF2-dependent regulator of CD8+ T cell exhaustion.
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RT @jakescottMD: If anyone claims vaccines haven’t been properly studied, show them this:. We’ve now logged 500 randomized, controlled vacc….
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Small molecule OPA1 inhibitors amplify cytochrome c release and reverse cancer cells resistance to Bcl-2 inhibitors #mitochondria
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RT @J_Cell_Sci: In their Cell Science at a Glance article, Antigoni Diokmetzidou & Luca Scorrano @LabScorrano summarise the mitochondrial c….
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RT @Pluchinolab: Delighted to see this finally out - kudos to @Dr_LPJ & friends!.Neural stem cell grafts remyelinate MS-like lesions in mic….
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RT @prof_horvath: Challenging a longevity dogma in muscle aging. Validated epigenetic clocks (pan-mammalian and muscle-specific) reveal a s….
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RT @_CVasilescu: Selfish mutations promote age-associated erosion of mtDNA integrity in mammals | Nature Communications..
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RT @_CVasilescu: Excellent #MitochondrialDisease selection of papers from #Week27! 📚. @Bims_BiomedNews @gavinmcstay….
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RT @manorlaboratory: My lab’s 5-year NIH R01 grant, awarded to study gene therapy for hearing loss, was abruptly terminated. I want to shar….
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