Dr. Rebecca Walker
@RebLWalker
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Computational Biologist | Former IBD + microbiome Postdoc @TheXavierLab @Broadinstitute | Bioinformatics PhD + neuropsychiatric genomics @GeschwindLab @UCLA
Seattle, WA
Joined November 2018
RT @TouficMayassi: 1/ Keen to share the story of my postdoc research in @TheXavierLab! We built a massive resource characterizing the spati….
www.nature.com
Nature - Intestinal regionalization is characterized by robust and resilient structural cell states and the intestine can adapt to environmental stress in a spatially controlled manner through...
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RT @TheXavierLab: Excited to share our latest study uncovering gut microbes and microbial metabolites linked to cardiovascular health! We s….
www.cell.com
The gut microbiomes and metabolomes of 1,429 participants from the Framingham Heart Study were comprehensively profiled toward the identification of associations between microbes, metabolites, and...
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RT @ChemicalBiology: Human lectins a part of our innate immune system, they influence the #microbes that live in us. What species do they b….
www.science.org
Soluble human lectins bind distinct bacterial species in fecal microbiota.
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RT @mikejg84: Our latest preprint, profiling gene regulation in >670 developing human brains! . Driven by exceptional PhD student @cindywe….
www.medrxiv.org
Genomic regulatory elements active in the developing human brain are notably enriched in genetic risk for neuropsychiatric disorders, including autism spectrum disorder (ASD), schizophrenia, and...
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RT @LyleMcPherson1: Excited to share a pre-print of our work in the @KiesslingGroup describing interactions between human lectins and stool….
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RT @ericmichbrown: Ever wondered how oral microbes colonize the gut? Turns out gut inflammation opens up a niche Veillonella can exploit th….
www.nature.com
Nature Microbiology - The oral bacterium Veillonella parvula utilizes inflammation-associated nitrate to facilitate colonization of the intestinal tract, which is observed in a mouse model of...
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Congrats @DanielRojas150 @ericmichbrown !! Happy to be a (small) part of this work.
Check out our study in @NatureMicrobiol describing how oral microbe #Veillonella parvula switches its metabolism to utilize inflammatory nitrate & colonize the gut.
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Congrats Thomas!.
Among billions of potential microbiome epitopes hide few immunodominant 'keystone' epitopes recognized by T cells. Out today in @ImmunityCP, we discover keystone epitopes and show T cell responses to reflect intestinal immune health.
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Check out my latest work exploring the gut microbiome of the Framingham Heart Study participants.
Out now in @GenomeMedicine! Read about our latest efforts, led by @RebLWalker, exploring associations between diet, lifestyle, & cardiometabolic disease phenotypes w/the gut #microbiome among the @FraminghamStudy participants.
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RT @ericmichbrown: Super excited to be able to share this study on gut microbiome ADP-ribosyltransferases and their role as phage-encoded f….
www.cell.com
Brown et al. report prevalent ADP-ribosyltransferases in gut microbiome commensals that are associated with bacteriophage elements and secreted as active enzymes. An abundant ADP-ribosyltransferase...
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RT @NatureNeuro: Examination of gene co-expression network architecture in human brain samples from @GTExPortal ; new from @GeschwindLab an….
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RT @TheXavierLab: Multi-omic profiling in IBD patients initiating biologic therapy identifies remission-associated gut microbial features.….
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RT @chirag_msk: A comprehensive, integrated review of unconventional T cells- excellent stuff from @TouficMayassi-
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RT @TheXavierLab: We are excited to share work by @johannesfscheid, @cobarnes27, and @basak_ersln with @bjorkmanlab, Regev lab, and @PaulBi….
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RT @TheXavierLab: In a collaboration with the Weersma lab out now in .@NatureComms, we show that intestinal mucosa cis-eQTLs in IBD can dep….
www.nature.com
Nature Communications - Inflammatory bowel diseases are heterogeneous, and little is known about how underlying genetic variation can affect their development. Here, the authors report that...
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RT @cssmillie: The Smillie Lab opens March at @MGHMedicine! We develop methods (wet/dry) to understand microbial life on the human body #mi….
www.smillielab.org
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RT @DrBiden: Together, we will build a world where the accomplishments of our daughters will be celebrated, rather than diminished.
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RT @adynhealth: Ready to work at a mission driven company? Want to use your talents to help us attain health equity? Join us! We are hiring….
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Congrats @NickyNeuro!!.
Now out! From @GeschwindLab @UCLA : Abnormal social and repetitive behaviors and elevated striatal dopamine, a molecular hallmark of human psychosis, in a Maternal Immune activation non-human primate model
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