Michael Gandal
@mikejg84
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Hetznecker Associate Professor, Psychiatry & Genetics at Penn/CHOP. Developmental brain genomics & dad jokes
Philadelphia, PA
Joined October 2011
New in @ScienceMagazine: Our paper mapping gene/isoform/splicing regulation at pop-scale during human #neurodevelopment. Major developmental shifts in #genetic reg.,.New colocalized risk genes at ~60% of #psych #GWAS loci. #PsychENCODE24.
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RT @QuantPsychiatry: Important new meta-analysis shows no link between in-utero MPH, AMPH, or atomoxetine exposure and any NDD outcome. Gre….
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RT @biorxiv_genetic: Phenotypic analysis of 11,125 trio exomes in neurodevelopmental disorders #biorxiv_genetic.
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Fascinating study comparing >200k veterans started on GLP-1R agonists for diabetes vs 1.2M started on other T2D meds, tracking 175 outcomes over 3.7 yr. 10-20% reduction in neuropsych outcomes, including schizophrenia, SUD.
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RT @CHOP_Research: The @Penn @ChildrensPhila Lifespan Brain Institute held its 2024 symposium, "Pathways to Psychosis," Nov. 4, featuring….
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Decoding sequence determinants of gene expression in diverse cellular and disease states | bioRxiv
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RT @tycheleturner: Excited to share that denovo-db is now available on @ZENODO_ORG (! The new version of denovo-db….
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RT @MolecularCell: Online Now: Large-scale map of RNA-binding protein interactomes across the mRNA life cycle https….
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RT @ophirshalem: Excited to see the revised version of our paper now published at @CellGenomics led by @YSereb .
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Really wild to see so many positive results for GLP1 drugs in large double blind RCTs — 30% decrease in COVID mortality
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RT @CHOP_Research: New research from @ChildrensPhila’s Gandal Lab + the Lifespan Brain Institute shed light on the genetic underpinnings of….
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What if Facebook actually followed the (sensible) advice of its own Llama3 AI platform on how to mitigate social media's exacerbation of our current mental health crisis:
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RT @clintomics: New review from @coletrapnell summarizing major statistical inference methods applied to single-cell, spatial, perturbati….
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RT @LM__Hernandez: 📢 We're hiring! 📢.We have an immediate opening for a postdoc to work on neuroimaging-genetics at UCLA. Interested in lin….
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RT @doyouseewhy: How do quantities of brain cells – the fundamental unit of life – differ in Alzheimer’s disease, schizophrenia and autism?….
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See Chloe's overview 👇.
How do quantities of brain cells – the fundamental unit of life – differ in Alzheimer’s disease, schizophrenia and autism? Our work on cell-type proportion shifts using methylomics is just out in @ScienceAdvances #PsychENCODE @mikejg84 @DanielVo10 🧵.
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