NMR spectral analysis using neural networks

N-glycans in a new role and, perhaps, another glyco-checkpoint !N-glycans on glycosylated RNAs hide self-RNA from endosomal Toll like receptors promoting silent clearance of dead cells | Nature.

US-FDA grants accelerated approval to a new oral drug for diffuse midline glioma (brain tumor) in adults and children

RT @Nature: Replenishing the brain’s natural stores of lithium can protect against and even reverse Alzheimer’s disease. .

RT @salonium: In the chart below, you can see this decline across age groups. Across all ages, the risk of death from cardiovascular diseas….

Great article: The progress in surgery, drugs, prevention, and emergency response has driven down death rates from heart disease and stroke dramatically — what led to this revolution saving millions of lives?

RT @Aiims1742: 🤯 🦠 🫁 ♋️ (@Nature) .Respiratory viral infections awaken metastatic breast cancer cells in lungs.

Resolution enhancement by sequential imaging with metabolic labelling, enabling the visualization of individual sugars within glycans on the cell surface: Images of the glycocalyx with resolution down to 9 Å in an optical microscope. Nature Nanotechnology

RT @yaireinhorn: 1/Here’s an excellent Financial Times article which accurately describes the problematic situation which many big Pharma c….

RT @CEPIvaccines: Nipah virus kills up to 75% of those infected, yet there are no approved vaccines to defend against it. CEPI is a lead f….

“Could a current second-line therapy, methotrexate, be equally effective as steroids, perhaps with fewer adverse events for pulmonary sarcoidosis” | NEJM

RT @mvaduganathan: 🚨 Finerenone Approved by US FDA in HF based on #FINEARTSHF. Finerenone (Kerendia) is a non-steroidal.MRA indicated to re….

RT @rust_ruslan: Microglia replacement halts the progression of microgliopathy in mice and humans | Science

RT @DeepaHRajan: Our paper on single-cell learning is now published in @CurrentBiology! .@WallaceUcsf .

RT @MazDivangahi: Thrilled to share our study @ImmunityCP how a TB-vaccine (BCG) and a fungi fragment (b-glucan) synergistically train neu….

The chimeric antigen receptor (CAR) T cell therapy for cancers impaired cognitive function and induced a persistent CNS immune response characterized by microglial reactivity, chemokine expression, and elevated CSF cytokines and chemokines : Cell

RT @JaviGBermudez: My lab's first paper is out in @Nature. We show that lipoprotein uptake protects tumors from ferroptosis by delivering t….

RT @davidasinclair: NEW STUDY: More than twice as many diabetic patients exposed to GLP-1 RAs (Ozempic, Wagovy, Mounjaro) developed age-rel….

In ER-positive, HER2-negative advanced breast cancer, vepdegestrant was associated with significantly longer progression-free survival than fulvestrant in the subgroup with ESR1 mutations but not in the full patient population | NEJM

AbSet: This data set provides a comprehensive data set composed of standardized experimental structures of antibody–antigen complexes extracted from the RCSB PDB and represented through molecular descriptors at the residue level