John Andrew Todd
@ProfJohnATodd
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Joined November 2016
Dr Elizabeth Robertson from @DiabetesUK @ERobertson02 talking about increasing prevalence of diabetes in UK and what charity is doing to improve diagnosis, prevention and treatment for people with diabetes @SouthAsianHF #SAHF25
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A new round of Oxford-GSK Clinical DPhil applications are open, deadline Dec 2nd. If you are ST4 and above, check out the projects in neurodegeneration, liver, respiratory and fibrotic pathology.
ox.ac.uk
About the courseThe DPhil in Biomedical and Clinical Sciences (Oxford-GSK) aims to address an unmet need among clinicians for training in data science and translational medicine.ย
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Congratulations to @KEMRI_Wellcome and @EdwineBarasa. Looking forwards to continuing our partnership
Congratulations to Professor @EdwineBarasa on being appointed as the Executive Director of @KEMRI_Wellcome , following the completion of a highly competitive recruitment process conducted by the Programmeโs partners: @UniofOxford,@KEMRI_Kenya and @wellcometrust. Read more here :
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I am proud to share that #TrinityChallenge is speaking at the @FAOconference in Rome alongside Youth Winners Salman Khan @reactgroup and Ednah Wanjiru @afri_ISAAA to showcase their #Biosecurity and animal health campaigns. Find out more about the projects:
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About 1 in 2 cancer patients are eligible for immunotherapy (with a PD1 antibody) but only 1 in 5 respond One reason is immune system aging: immunosenescence But senolytics - which eliminate aged cells - can strengthen immunotherapy (in mice, here, then a clinical trial)
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And now the fourth preprint from the TenK10K phase 1 dataset, led by @anglixue from @drjosephpowell's team - this time looking at genetic impacts on cell type-specific chromatin accessibility in 1,000 individuals, who also have scRNA-seq!
New preprint alert: https://t.co/RugxCYzlSH. Excited to share our analysis on the impact of genetic variants on single-cell chromatin accessibility in blood, using scATAC-seq and WGS from over 1,000 donors and 3.5M nuclei as part of TenK10K phase 1 ๐งฌ ๐งต๐ (1/n)
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Probably the most promising use of proteomics in drug development is creating signatures that act as surrogates for hard endpoints in early phase trials. In a MASH trial, semaglutide showed dose-dependent effects on serum proteomic signatures of liver histology mirroring actual
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Not just shingles vaccine, but also RSV vaccine reduces the risk of dementia, which highlights the benefit of revving up the immune system in older individuals https://t.co/DB4Auzdp28
nature.com
npj Vaccines - Lower risk of dementia with AS01-adjuvanted vaccination against shingles and respiratory syncytial virus infections
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@nicolesoranzo @ERC_Research @humantechnopole @sangerinstitute @Cambridge_Uni Amazing, congrats @nicolesoranzo, well deserved indeed! ๐
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The difference between 100% and 99% automation is massive. In the first, wages increase then collapse.
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๐๐ What a great event! Our CEO attended to give a talk on 'How the discovery of ReNU syndrome is impacting patients and families', which you can now watch in the recordings linked below. https://t.co/aZtwJUn1bI
cpm.ox.ac.uk
If you missed it, the videos from our event about the discovery of ReNU syndrome are available to watch here: https://t.co/EKMHsCAnJ5
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We're thrilled that Professor Peter Flatt has been awarded an MBE in the Kingโs Birthday Honours list โ a richly deserved recognition of his outstanding career in #diabetesresearch ๐ A thread ๐
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Ben Todd has written the best thing on how to plan your career given AI/AGI. Will thread. A very plausible scenario is salaries for the right work go up 10x over a ~decade, before then falling to 0. So we might be heading for a brief golden age followed by crazy upheaval. 1/
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Awesome @StanfordOTL spotlight on Appel Sauce Studios, who is commercializing the injectable hydrogel depot technology we've developing over the past few years @stanford @StanfordMSE: https://t.co/hTYqYe0QV2
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Huge pleasure to meet Charlotte whose new book will be dynamite to medical pretensions but huge force for patient empowerment. Anyone who's trying to envision AI-informed models of care needs to talk to @crblease And by the way, there is no other future for medicine.
Finally got to meet @RichardLehman1 at the august Royal Society of Medicine, Marylebone, London before taking our conversation elsewhere. Good to talk to someone thinking freely, frankly, and deeply about the future of patient care, and of the medical profession.
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Our systematic review and meta-analysis shows that in children with early-stage #T1D the OGTT, related tests (M120 and Index60) and HbA1c predict progression to clinical #T1D. More evidence is needed for other tests, such as CGM and C-peptide. @BesserBesser @T1Early @diabmedwiley
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Children with early-stage T1D are being managed by our paediatric diabetes colleagues across the UK. Our UK-wide survey outlines the current status of their management, and the need for a UK-consensus approach to early stage T1D https://t.co/Ss5GanRSj3
onlinelibrary.wiley.com
Click on the article title to read more.
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Congratulations to the eight NDM researchers who have been awarded Associate Professorships in recognition of their research or teaching ๐๐ @NayiaPetousi @Alice_J_Norton @BetterKidneys @aabdi78_abdi Read more ๐ https://t.co/5iPqc02Ap6
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Oxford and Thai health officials have signed a Memorandum of Understanding to collaborate on research with the aim to prevent and control the key #InfectiousDiseases affecting the Thai-Myanmar border ๐น๐ญ ๐ฒ๐ฒ ๐ฆ @MORUBKK Find out more ๐ https://t.co/QrkCjbn8Uv
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