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Natalie Porat-Shliom Profile
Natalie Porat-Shliom

@PoratShliomLab

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Cell Biologist and microscopist. My lab @theNCI focuses on mitochondria, metabolism and liver cancer. Views are my own #cellbiology #microscopy

Bethesda, MD
Joined November 2012
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@PoratShliomLab
Natalie Porat-Shliom
7 months
Preprint alert!! How zonated hepatocytes adapt to changes in lipid influx due to fasting or a Western diet (WD). We developed a microscopy-based phenotyping method called single-cell phenomics (scPhenomics) to measure the features of mitochondria and lipid droplets (LDs).
@biorxiv_cellbio
bioRxiv Cell Biology
7 months
Spatially resolved rewiring of mitochondria-lipid droplet interactions in hepatic lipid homeostasis. #biorxiv_cellbio.
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@PoratShliomLab
Natalie Porat-Shliom
1 month
RT @AdrianoAguzzi: Two papers, three dimensions! Anna Maria Reuss describes a generic technique for 3D-histology of human archival paraffin….
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@PoratShliomLab
Natalie Porat-Shliom
1 month
RT @MariaBohnert: Our new preprint on metabolic adaptation of the nucleus vacuole junction NVJ is online! Big thank you to @MarieHugenroth….
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@PoratShliomLab
Natalie Porat-Shliom
1 month
RT @nieminm: Very excited to share our latest work, “Mitochondrial presequences harbor variable strengths to maintain organellar function,”….
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@PoratShliomLab
Natalie Porat-Shliom
1 month
RT @OlzmannLab: Thrilled this paper is out! We solved the first cocrystal structure of FSP1 with an inhibitor (FSEN1), providing mechanisti….
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@PoratShliomLab
Natalie Porat-Shliom
2 months
RT @amtya21: Excited to present first publication from the Joshi lab, now in @JCellBiol. Here, we show that phosphatidic acid regulates Pe….
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@PoratShliomLab
Natalie Porat-Shliom
2 months
One of my favorite podcasts!.
@ItaiYanai
Itai Yanai
2 months
Have you discovered the Night Science Podcast yet?.@nightsciencepod
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@PoratShliomLab
Natalie Porat-Shliom
2 months
RT @BiancaSchrul: The abstract submission deadline for the 2nd edition of our #EMBOLipidDroplets Workshop (21-26 September 2025) is approac….
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@PoratShliomLab
Natalie Porat-Shliom
2 months
Milestones is an annual publication covering the exciting research performed @theNCI @IRPatNIH. This year, my group's study on hepatic mitochondria was beautifully covered alongside clinical, translational, and basic research. Honored to be included!.
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@PoratShliomLab
Natalie Porat-Shliom
2 months
RT @J_Cell_Sci: Jason Casler @JasonCasler1, Clare Harper and Laura Lackner find that mitochondria–plasma membrane contact sites regulate th….
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@PoratShliomLab
Natalie Porat-Shliom
2 months
RT @HenneLab: Proud present our latest work led by @_blessypaul, now in Developmental Cell @Dev_Cell. Here, we characterize an ER-localiz….
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@PoratShliomLab
Natalie Porat-Shliom
2 months
RT @OlzmannLab: Reminder: The 1st FASEB #Ferroptosis Meeting is this summer! Spectacular speaker lineup + short talks selected from submitt….
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@PoratShliomLab
Natalie Porat-Shliom
2 months
RT @AssafZaritsky: MBoC (@ASCBiology Society Journal) is looking for Early-Career Editorial Board Members! . Subm….
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@PoratShliomLab
Natalie Porat-Shliom
2 months
RT @NASH_and_coffee: A mentor, colleague and friend, Theo is an excellent physician-scientist working to establish knowledge and develop ne….
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@PoratShliomLab
Natalie Porat-Shliom
2 months
RT @metaboflo: ⏰ Don’t miss the chance to apply for this postdoc opportunity in spatial & single-cell proteomics in our lab @karolinskainst….
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@PoratShliomLab
Natalie Porat-Shliom
3 months
RT @metaboflo: Keen on a cutting-edge postdoc at the interface of bio and tech? Join us at Karolinska Institutet to unravel metabolic stres….
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@PoratShliomLab
Natalie Porat-Shliom
3 months
Have you ever wondered if liver zonation is conserved from mice to humans? And how does fibrosis affect zonation in patients? Now, these questions are answered using scDVP. Some collaborations are meant to be.@CarolineWeiss30.@metaboflo.@labs_mann.@MLSB_Borgwardt.
@labs_mann
Matthias Mann Lab
3 months
Introducing our single-cell DVP framework combining strategic cell selection with protein gradient mapping algorithms. Analyzing hepatocyte proteomes across 18 human livers, revealing cross-species differences, and mapping disruptions in liver fibrosis.
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@PoratShliomLab
Natalie Porat-Shliom
3 months
RT @CarolineWeiss30: Preprint alert ‼️. Excited to share our work investigating liver zonation in human health and disease with our advance….
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@PoratShliomLab
Natalie Porat-Shliom
3 months
Looking forward to this 😍.
@cohenlaboratory
Sarah Cohen
3 months
I am beyond thrilled to co-organize this FASEB #LipidDroplet conference with Mike @HenneLab in 2026! Check out the lineup and plan to participate - you do not want to miss this one!! #lipidtime.
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@PoratShliomLab
Natalie Porat-Shliom
3 months
RT @BonifacinoJuan: Our lab at the NIH (Bethesda, MD) is looking for postdocs to join our team studying the molecular mechanisms of protein….
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@PoratShliomLab
Natalie Porat-Shliom
3 months
RT @HenneLab: Very proud of post-doc Holly Merta @HollyMerta and her work characterizing Calmin, a molecular tether that regulates focal ad….
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