Natalie Porat-Shliom
@PoratShliomLab
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Cell Biologist and microscopist. My lab @theNCI focuses on mitochondria, metabolism and liver cancer. Views are my own #cellbiology #microscopy
Bethesda, MD
Joined November 2012
Preprint alert!! How zonated hepatocytes adapt to changes in lipid influx due to fasting or a Western diet (WD). We developed a microscopy-based phenotyping method called single-cell phenomics (scPhenomics) to measure the features of mitochondria and lipid droplets (LDs).
Spatially resolved rewiring of mitochondria-lipid droplet interactions in hepatic lipid homeostasis. #biorxiv_cellbio.
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RT @AdrianoAguzzi: Two papers, three dimensions! Anna Maria Reuss describes a generic technique for 3D-histology of human archival paraffin….
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RT @MariaBohnert: Our new preprint on metabolic adaptation of the nucleus vacuole junction NVJ is online! Big thank you to @MarieHugenroth….
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RT @nieminm: Very excited to share our latest work, “Mitochondrial presequences harbor variable strengths to maintain organellar function,”….
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RT @OlzmannLab: Thrilled this paper is out! We solved the first cocrystal structure of FSP1 with an inhibitor (FSEN1), providing mechanisti….
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RT @amtya21: Excited to present first publication from the Joshi lab, now in @JCellBiol. Here, we show that phosphatidic acid regulates Pe….
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One of my favorite podcasts!.
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RT @BiancaSchrul: The abstract submission deadline for the 2nd edition of our #EMBOLipidDroplets Workshop (21-26 September 2025) is approac….
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RT @J_Cell_Sci: Jason Casler @JasonCasler1, Clare Harper and Laura Lackner find that mitochondria–plasma membrane contact sites regulate th….
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RT @HenneLab: Proud present our latest work led by @_blessypaul, now in Developmental Cell @Dev_Cell. Here, we characterize an ER-localiz….
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RT @OlzmannLab: Reminder: The 1st FASEB #Ferroptosis Meeting is this summer! Spectacular speaker lineup + short talks selected from submitt….
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RT @AssafZaritsky: MBoC (@ASCBiology Society Journal) is looking for Early-Career Editorial Board Members! . Subm….
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RT @NASH_and_coffee: A mentor, colleague and friend, Theo is an excellent physician-scientist working to establish knowledge and develop ne….
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RT @metaboflo: ⏰ Don’t miss the chance to apply for this postdoc opportunity in spatial & single-cell proteomics in our lab @karolinskainst….
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RT @metaboflo: Keen on a cutting-edge postdoc at the interface of bio and tech? Join us at Karolinska Institutet to unravel metabolic stres….
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Have you ever wondered if liver zonation is conserved from mice to humans? And how does fibrosis affect zonation in patients? Now, these questions are answered using scDVP. Some collaborations are meant to be.@CarolineWeiss30.@metaboflo.@labs_mann.@MLSB_Borgwardt.
Introducing our single-cell DVP framework combining strategic cell selection with protein gradient mapping algorithms. Analyzing hepatocyte proteomes across 18 human livers, revealing cross-species differences, and mapping disruptions in liver fibrosis.
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RT @CarolineWeiss30: Preprint alert ‼️. Excited to share our work investigating liver zonation in human health and disease with our advance….
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Looking forward to this 😍.
I am beyond thrilled to co-organize this FASEB #LipidDroplet conference with Mike @HenneLab in 2026! Check out the lineup and plan to participate - you do not want to miss this one!! #lipidtime.
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RT @BonifacinoJuan: Our lab at the NIH (Bethesda, MD) is looking for postdocs to join our team studying the molecular mechanisms of protein….
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RT @HenneLab: Very proud of post-doc Holly Merta @HollyMerta and her work characterizing Calmin, a molecular tether that regulates focal ad….
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