Univ. of Pennsylvania Department of Cancer Biology
@Penn_CBIO
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Official Twitter of the Department of Cancer Biology at The University of Pennsylvania (@Penn) Perelman School of Medicine (@PennMedicine). Tweets are our own.
Philadelphia, PA
Joined September 2021
ER stress tolerance is regulated by copper-dependent PERK kinase activity ft. Sarah Newton (@BB_UPenn), @bradylabupenn (@Penn_CBIO), Xinglong Shi, Noah Beratan, Jitendra Arya, Margaret Bond, Cagla Akay-Espinoza & @KJSsci (@PennDental) @CellReports
https://t.co/3yUKWEQVdc
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.@AngieDemichele joined @FOX29philly to discuss a clinical trial for preventing cancer recurrence, and how it’s helped the study’s participants, like breast cancer survivor Illeana Casiano-Vazquez, feel more in control of their future. @PennBreastTCE
fox29.com
Penn Medicine Oncologist, Dr. Angela DeMichele, and breast cancer survivor, Illeana Casiano-Vazquez, join Good Day Philadelphia to discuss a groundbreaking clinical trial that effectively treats...
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Systematic evaluation of GAPs and GEFs identifies a targetable dependency for hematopoietic malignancies ft. Yuqiao Liu & @junwei_s (@Penn_CBIO) @CD_AACR
https://t.co/gnC1Am9Lh4
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Congratulations to @bradylabupenn (@Penn_CBIO/ @RTAatPennMed), recipient of the 2026 @ASBMB Ruth Kirschstein Award for Maximizing Access in Science! https://t.co/qSQj5NC7fb
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A 1st-of-its-kind clinical trial identified risk of breast cancer recurrence & successfully treated dormant tumor cells using existing drugs ft. @AngieDemichele (@PennCancer) & Lewis Chodosh (@Penn_CBIO) https://t.co/twZ1RIlxjm
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📢 TODAY, September 11th, beginning at 10am, join us in the Smilow Lobby for Cores Day 2025 to learn more about the many outstanding biomedical research resources & services available across @PennMedicine, @ChildrensPhila, @PennVet & @TheWistar! https://t.co/VfOKUbHki0
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New proof-of-concept trial by @PennMedicine in @NatureMedicine researched dormant DTCs link to breast cancer recurrence. The CLEVER trial showed HCQ and EVE reduced DTCs & improved recurrence-free survival. Read more here 🔗: https://t.co/sZMrgipW46
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ft. Siera Tomishima, Dale Kim, @YohanizOrtega, Paula Oliver (@PennPathLabMed), Robert Bowman (@Penn_CBIO), Nadia Porter, Ipsita Guha, @dar_darasif, Jennifer Roof, Hossein Fazelinia, Lynn Spruce & Christopher Thom (@CHOP_Research) https://t.co/U4XPHEApXq
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Congratulations to @LilingWanLab (@Penn_CBIO/ @PennCancer), recipient of a 2025 @PershingSqFdn Sohn Cancer Prize! https://t.co/A5ckwu8TgF
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We’re proud to partner with @PennCancer to support six SUIP 2025 cohort members! Thankful to @AmericanCancer for research training funds!
We’re halfway through SUIP 2025, and the progress has been inspiring! From mastering journal club and lab techniques to exploring cutting-edge topics like microbiome-immune interactions, cancer therapy, and epigenetics, our students are diving deep into research! 💡🧪 #SUIP2025
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Learn more about 2-PREVENT Breast Cancer Translational Center of Excellence led by @AngieDemichele & @Penn_CBIO Chair Lewis Chodosh.
Keeping cancer conquered ft. @AngieDemichele, @AmaravadiRavi, Kevin Fox (@PennCancer), Lewis Chodosh (@Penn_CBIO), Jerry Rosenbloom (@Wharton), Andrea Orsher & Robert Orsher (@Pennalumni) https://t.co/VH39C1EfgI
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#ICYMI: Nominations for the @PennMedicine Awards of Excellence, which recognize our faculty's exceptional achievements in mentoring, professionalism, research & clinical work, are open through Friday, 6/20! Learn more➡️ https://t.co/cBuAps6ua4
#PSOMAOE
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Congratulations to @GMBurslem and the Burslem lab on their work describing a new tool to achieve endogenous protein editing including noncanonical residue incorporation!
Intracellular protein editing & noncanonical residues in endogenous proteins ft. @JennaNBeyer, Kaitlyn Toy, @MohammadAltafN3, @NRaniszewski1, @GMBurslem (@BB_UPenn), @YSereb, @efeierman, @korblab & @ophirshalem (@PennGenetics) @PennEpiInst @Penn_CBIO
https://t.co/RXrs3v6ZAf
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New research out in @NatureSMB provides insight into the molecular glues that inhibit deubiquitylase activity & inflammatory signaling ft. Smita Bhutda, @arindam_datta1, Daniel Stein & @RogerRogergr (@Penn_CBIO) https://t.co/iE7xXNoTG1
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.@PennMedicine at the 2025 @AACR Annual Meeting ft. @berger_lab, Celeste Simon (@PennCDB), Katy Wellen, Luca Busino (@Penn_CBIO), @arjunrajlab (@PennGenetics), @BenStanger01, @KLNathanson (@PennCancer), Costas Koumenis (@PennRadOnc) & Ellen Puré (@PennVet) https://t.co/oPG6qQ7aQL
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Our lab has opened @Penn_CBIO @BasserBRCA @PennCancer @PennMedicine! We study new mechanisms of hereditary cancers and implications for sporadic cancers, building on my training with @LabJacks and @BruggeMe. Join us: https://t.co/U7hyH5ag9S! Follow us: https://t.co/ON6JekYfP8
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A recent paper published in @Nature, feat. co-author @ronny_drapkin, Director of Gynecologic Cancer Research, sheds light on the impact of BRCA mutations, age, surgical indication, & hormone status on the molecular phenotype of the human Fallopian tube:
nature.com
Nature Communications - The human Fallopian tube (FT) is implicated as a site of origin for pelvic serous cancers. Here the authors conduct multi-omics analysis on over 100 FTs. The results...
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Catch Donita Brady (@bradylabupenn, @Penn_CBIO, @Penn) at @CellSymposia #CSMetabolites2025 as she presents 'Mitochondrial Cu Sensing via Metabolism and Signaling'—happening next month in Sitges, Spain. Register today!
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We are excited to announce the Basser Postdoctoral Fellowship Program (BPFP) that will provide financial for a postdoctoral fellow for up to three years. 💻: Learn more and apply by 5/30/25: https://t.co/PT1TNROgzo
@PennCancer @PennMedicine @PennMDForum
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Huang et al. demonstrated that inducible TOX deletion in established LCMV-specific exhausted T cells (Tex) after chronic infection impaired their durability and differentiation. https://t.co/jptRszfHRs @Penn_CBIO @parkerici
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