Junwei Shi
@junwei_s
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Associate Professor at UPenn
Philadelphia, PA
Joined March 2013
Excited to share our new work on direct protein-based genome editing in primary cells. We termed it Peptide-Assisted Genome Editing (PAGE) CRISPR-Cas platform. This platform allows rapid and effective editing of primary cells with minimal toxicity.
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RT @Berrios_KN: The last lead author article from my PhD is out! In @NAR_open, we report our mechanistic study on how Cas9 and AID enzymes….
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RT @Berrios_KN: 1/Excited to share my first author publication where we create split-engineered base editors (seBEs). Here, we place base e….
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RT @Tcellogic: Fascinating discovery by @Annaglobig! Exhausted CD8 T cells talk to sympathetic nerves in tissues & tumors. Tex cells exp….
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RT @hsiung_chris: Excited to share our (with @LukeGilbertSF) new preprint ( on a new combinatorial functional genom….
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RT @Penn_CBIO: Welcome to our newest @Penn_CBIO faculty member Dana Silverbush @DSilverbush whose lab will harness multi-omics, machine lea….
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RT @wellhausrn: I am excited to share that my PhD work on “Epitope base editing CD45 in hematopoietic cells enables universal blood cancer….
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RT @LukeGilbertSF: In vivo perturb-seq in cancer and immune cells with @sjohnliu and @LabRaleigh. Excited for this….
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Awesome work from the Wu Lab! Congrats to all the co-authors!.
Thrilled to see our single-cell DNA (hydroxy)methylome sequencing method out ( ! Interdisciplinary efforts from talented first authors: @ebfabyanic (Emily's thesis project), Peng - @PengHu_xqq, and Qi - @QiQiu8788 !.
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Our department is recruiting new faculty! I can't emphasize enough how supportive both the department and the scientific community are. Feel free to DM me if you have any questions.
🚨Our 2024 departmental faculty search is live! @PennMedicine Cancer Biology is recruiting for tenure-track Assistant Professors positions. Applicants with expertise in any area of cancer biology are encouraged to apply. 👇
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RT @dow_lab: Paper day! This one is a fantastic joint effort from @alynakatti and @AdrianVegaPerez. I tweeted about this >1 year ago when….
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Friends, I will be in Boston next Thurs 7/13. Anyone wants to catch up there?.
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RT @NatureBiotech: Peptide-assisted genome editing enables efficient single and multiplex editing in hematopoietic cells .
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RT @GenomeTDCC: 📢Direct Enzymatic Sequencing of 5mC at Single-Base Resolution - out today in @nchembio .👉@KohliLab….
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RT @AleksiaBarka: It was exciting to review @liaulab’s cutting-edge use of CRISPR tiling screens to uncover drug addiction mutations & a cr….
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Such a great time working together. I am always down for more in vivo T cells CRISPR screenings.
New work from @amylizbaxter with @junwei_s and Martha Jordan. The SWI/SNF complex has received attention for its role in CD8 T cells. Now, new insights into specific control of Exhausted CD8 T cells by PBAF. Also see related work from @Tcellogic
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Congrats! @amylizbaxter. It was such a fantastic experience to work together with you on this work.
Super excited to share our work on the differential roles of distinct versions of SWI/SNF chromatin remodelling complexes in CD8 T cell exhaustion! A huge team effort from labs of @EJohnWherry , Martha Jordan and @junwei_s.
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RT @amylizbaxter: Super excited to share our work on the differential roles of distinct versions of SWI/SNF chromatin remodelling complexes….
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RT @CAMBUpenn: Congratulations to Zhendong Cao @TomZhendong who was a member of the Shi lab @junwei_s
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