monosov_lab
@MonosovLab
Followers
2K
Following
3K
Media
42
Statuses
3K
Studying neuronal circuits of motivation, emotion, and learning in the Department of Neuroscience at Washington University School of Medicine. Opinions are own.
St Louis, MO
Joined July 2016
In this review I discuss the circuitry and neurobiological and algorithmic mechanisms of information- and novelty- seeking (ps. for those that already downloaded it, please re-download; as an issue in Fig.1 has been fixed since it came out a few days ago).
nature.com
Nature Reviews Neuroscience - Animals frequently engage in curiosity-related behaviours that appear to provide them with no immediate benefits. Monosov discusses the neural circuits in the primate...
0
13
40
Very cool.
Our new paper is out in Science. We identified a subgroup of cholinergic neurons that mediate sensory modality-specific attention. They change their funcitonal properties within secs of behavioral context change. Congrats to Bin and the team!.
0
0
1
RT @yulonglilab: Excited to share our Science paper on HaloDA1.0-the first genetically encoded far-red dopamine sensor! 🥳It enables powerfu….
science.org
Dopamine (DA) plays a crucial role in a variety of brain functions through intricate interactions with other neuromodulators and intracellular signaling pathways. However, studying these complex...
0
52
0
RT @ma_fakharian: First first-author paper now in @ScienceMagazine! Great thanks to incredible mentor @reziliusReza and coauthors @just_ald….
science.org
Null space theory predicts that neurons generate spikes not only to produce behavior but also to prevent the undesirable effect of other neurons on behavior. In this work, we show that this competi...
0
38
0
RT @StephensonJones: 🎉Thrilled that the lab’s first paper is out today in @Nature! Credit to the amazing @cesca_gst, @HernyMV and @YviJohan….
nature.com
Nature - Dopaminergic action prediction error signals are used by mice as a value-free teaching signal to reinforce stable sound–action associations in the tail of the striatum.
0
36
0
At JHU, our team will work on the circuit / algorithmic basis of intelligence & cognition, with attention to their malfunction in disease. We are looking for new team members with experience in circuit neuroscience, biology, or machine intelligence. Please DM if u are interested.
1
2
17
Some professional news : My team is moving to Johns Hopkins University this Summer. I am deeply grateful to Washington University for supporting us since 2014. It has been an amazing journey full of brilliant colleagues and friends.
6
1
42
So key.
John Hopfield on pursuing interesting things: “Doesn’t matter what they are - interesting is the important one”.
0
0
3
Huge team effort…. How science ought to work. Gratitude to all the authors across many labs, and their hard work and creativity. I am honored to work with Takaya Ogasawara and colleagues on this project.
0
0
5
New work! How does perceptual novelty impact the value of (physical) rewards: what are the underlying algorithms and neural mechanisms?. The answers may help construct smarter AIs & to understand how / why novelty seeking breaks in psychiatric disorders.
biorxiv.org
Perceptually novel objects have profound impacts on our daily decisions. People often pay to try novel meals over familiar ones, or to see novel visual scenes at art exhibits and travel destinations....
2
8
43
this is a fantastic choice! congratulations Whitney!.
We are excited to announce our 2025 Matches! Welcome on board! #uchicago #uchicagomedicine #matches2025
0
0
1
RT @RichardSSutton: I am pretty happy with this 30-minute summary of my views on the current state of AI and alignment. .
0
101
0
RT @guyd33: Out today in Nature Machine Intelligence! . From childhood on, people can create novel, playful, and creative goals. Models hav….
0
59
0
Incredibly proud of Dr Julia Pai. Fantastic defense and pioneering project on non-neuronal cells in Reinforcement Learning! Now almost off to her next chapter. Paper in prep!
0
3
18
i have made an account on bluesky. i will use it to post lab updates as i do here. those interested please follow:
0
0
0
RT @reziliusReza: In the cerebellum, neurons are placed in competition with one another, nulling the downstream effects of each other's spi….
0
24
0
RT @mousejesus: Kicking off the new year with our new paper in @Nature! We find that touch-guided tongue control in mice relies on a colli….
nature.com
Nature - Touch-guided tongue control in mice relies on a collicular mechanosensorimotor map, analogous to collicular visuomotor maps associated with visually guided orienting across many species.
0
38
0
RT @yulonglilab: (1/7) Far-red dopamine sensor is coming! Excited to introduce our chemigenetic DA sensor, HaloDA1.0! #Dopamine #FarRedSens….
biorxiv.org
Neurochemical signals like dopamine (DA) play a crucial role in a variety of brain functions through intricate interactions with other neuromodulators and intracellular signaling pathways. However,...
0
24
0