Yulong Li Lab
@yulonglilab
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Yulong Li: PKU (BS, Beijing) - Duke Univ. (PhD, Durham) - Stanford Univ. (Postdoc, Palo Alto) - PKU (Prof. , Beijing)
Beijing, China
Joined November 2018
(5/5) PGE2-1.0 sensor reveals notable spatiotemporal differences in brain PGE2 dynamics between inflammation and seizure models. This includes distinct kinetics and cortical distributions, contributing to further study of PGE2's roles. #PGE2 #GRAB_Sensors #neuroscience
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(4/5) Applying PGE2-1.0 in vivo: We monitored endogenous PGE2 dynamics with wide-field imaging and captured cortex-wide PGE2 changes during seizure.
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(3/5) Applying PGE2-1.0 in vivo: We monitored endogenous PGE2 dynamics with wide-field imaging and captured cortex-wide PGE2 changes during inflammation.
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(2/5) Introducing PGE2-1.0, our new GRAB sensor for Prostaglandin E2 (PGE2). It offers high specificity, nanomolar affinity, and rapid kinetics.
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(1/5) Excited to introduce PGE2-1.0, our new GRAB sensor for real-time tracking of prostaglandin E2! This powerful tool offers high spatiotemporal resolution to reveal PGE2 dynamics in inflammation, seizures, and more.
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RT @PKU1898: 🧠Imagine watching brain chemicals "talk" to each other in real-time!. #PKU's @yulonglilab and collaborators just achieved this….
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Amazing work by Yu Zheng (@yu98449099), Ruyi Cai (@_RuyiCai), and the whole team. Huge thanks to our fantastic collaborators: @muyuuyum, Zhixing Chen (@ZhixingChen2), Luke Lavis (@rhodamine110), Eric Schreiter (@ERSchreiter), Kai Johnsson, and Jonathan Grimm.
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Excited to share our Science paper on HaloDA1.0-the first genetically encoded far-red dopamine sensor! 🥳It enables powerful multiplex imaging in neurons, brain slices, and live animals.🧠🔬 #GRABsensors #Dopamine .
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Back in Canada after 20 years! 🍁 Honored to speak at #CANACN – big thanks to @CAN_ACN and the amazing organizers. So inspired by the science and energy here. Excited to reconnect and explore collaborations! @canna_brain @sjo09 @DrJKhokhar
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We independently have similar descriptions. 😀.
My new self-description: branch-lowering. Better than toolmaking, something I never really liked. "One of the deep problems we have in science is that we reward the people who pick the fruit rather than the ones who lower the branches.".
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Please apply!.
Enrollment Now Open! #CSHA 3rd Annual Summer Course on Modern Techniques in #Neuroscience: #Probes, Detections and Discoveries-organized by Yulong Li @yulonglilab & Tianyi Mao. Apply today at We are waiting for you in Suzhou China.
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Happy to be part of it and I will share latest progress in developing multicolor neuromodulator sensors for in vivo detection.
Today’s #EDRC2025 keynote speaker is Yulong Li from Peking University. His laboratory is renowned for its significant contributions to the development of fluorescent sensors for various neurotransmitters and neuropeptides used in a range of model organisms, including #Drosophila
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RT @miketadross: Honored to speak at Tsien@80—a beautiful reminder that mentorship, curiosity, and generosity leave the deepest legacy. Tha….
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Join the "Genetically-Encoded and Chemigenetic Tools for Analysis and Control of Biological Systems" symposium at #ChemPacific2025! Explore cutting-edge tools alongside other world-class science in Hawaii. 🏝️.
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RT @MCB_Harvard: Avoid or ignore? How the Brain Copes with a Potential Threat @naoshigeuchida @yulonglilab @malcgcamp @NatureNeuro @harvard….
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RT @kmcostalab: I am happy to share my latest (NIH funded) work, out in @CurrentBiology!. We show that task demands define the correlations….
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RT @JiefuBiol: A cross-disciplinary conference dedicated to the cell surface @janeliaconf @HHMIJanelia to connect tool developers and biolo….
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Huge congrats & thanks to Kouki Touhara, Nathan Rossen @RossenNathan, Fei Deng @FeiDeng23 and Joel Castro, et al., for their amazing work!.
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Real time imaging of 5-HT with the gGRAB5-HT3.0 sensor within crypts.
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