CMMC
@MicrobialCMMC
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Collaborative Microbial Metabolite Center
UC San Diego
Joined October 2024
Super exciting study linking diet to Colibactin producing bacteria and its impact on CRC. Check out our MOTM highlight on this at https://t.co/sNGeJPKvA1 or
Diets high in meat and low in fiber have been linked with a boost of colibactin-producing E. coli, damaging DNA, and leading to colorectal cancer Could the microbiome drive the current rise in colorectal cancer? https://t.co/n4d9zDUWo6
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antiSMASH 8.0: extended gene cluster detection capabilities and analyses of chemistry, enzymology, and regulation
academic.oup.com
Abstract. Microorganisms synthesize small bioactive compounds through their secondary or specialized metabolism. Those compounds play an important role in
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We are back again with the April Molecule of the month featuring Colibactin! Check out more at https://t.co/sNGeJPJXKt
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I went on a podcast again!! This time talking #cysticfibrosis, #coralreefs and all things science! Science is cool! @EddieBarstool and @BarstoolChief know this. So should you! @DogWalkBarstool
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Thrilled to share our latest research out today in @Nature: “Microbial metabolite drives ageing-related clonal hematopoiesis via ALPK1” https://t.co/xlcrZxKRU8
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It's out! It's out!! Our new paper on how conjugated bile acids affect gut inflammation is out in @NatureComms
nature.com
Nature Communications - Here, the authors show that both host and microbially conjugated bile acids (Bas) can provide benefits to IBD patients, but this is dictated by a delicate balance between BA...
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One new article about #MicrobialCoCulture: "Vibralactone derivatives isolated from co-cultures of the basidiomycetes #Stereum hirsutum and #Boreostereum vibrans"
link.springer.com
Natural Products and Bioprospecting - The basidiomycetes Stereum hirsutum and Boreostereum vibrans are two fungi of the same genus. In this study, chemical investigation on the co-cultures...
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Happy March! While there’s so much to say about our friendly neighborhood Riboflavin, here we show some highlights. It’s amazing how we can engineer bacteria for commercial production! Check out more at https://t.co/sNGeJPKvA1
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Have we finally discovered what a “normal” gut #microbiome looks like? Analysis of 45,454 microbiomes from 42 countries identified the Health-Associated Core Keystone (HACK) index, linking certain microbial profiles to lifestyle, disease, and health. https://t.co/jx5na9aWWo
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Human Untargeted Metabolomics in High-Throughput Gut Microbiome Research: Ethanol vs Methanol | Analytical Chemistry
pubs.acs.org
Untargeted metabolomics is frequently performed on human fecal samples in conjunction with sequencing to unravel the gut microbiome functionality. As sample collection efforts are rapidly expanding,...
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The International Space Station has a unique and extreme microbial and chemical environment driven by use patterns: Cell
cell.com
With long-term space travel and extraterrestrial habitation becoming feasible, understanding how space environmental exposures, microbial communities, and molecular profiles differ from Earth is...
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got microbial metabolites? Add to the public knowledgebase available through GNPS2! https://t.co/sNGeJPJXKt
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#CIMM2025 Speaker Spotlight: @lizljohnson’s research program focuses on understanding how lipids mediate diet-microbiome-host interactions with the goal of manipulating these interactions for the benefit of host health. Catch her presentation on Day 1!
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"Metagenomic estimation of dietary intake from human stool" #GutMicrobiome
https://t.co/kNslhuqB6a
nature.com
Nature Metabolism - Diener et al. present a method that allows the estimation of dietary intake from human stool by detecting food-derived DNA in faecal metagenomes.
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What if the gut microbiome drives sugar cravings? New research found the bacterium Bacteroides vulgatus was causally linked to intake of sugar, with pantothenic acid being the key metabolite involved: https://t.co/fxqFg2XAdT
nature.com
Nature Microbiology - Bacteroides vulgatus, a gut bacterium, promotes GLP-1 secretion through its metabolite, pantothenate, inhibiting sugar preference in mice.
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Check out our approach toward disciformycin and gulmirecin, spearheaded by @PeterRuehmann. @nyuchemistry @PennChemistry
https://t.co/REnDeKDS9v
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EasyMetagenome: A user‐friendly and flexible pipeline for shotgun #metagenomic analysis in #microbiome research https://t.co/LX3U4Y03SJ
#Bioinformatics #pipeline @wileymicrobio @WileyBiomedical
onlinelibrary.wiley.com
EasyMetagenome is a user-friendly shotgun metagenomics pipeline designed for comprehensive microbiome analysis, supporting quality control, host removal, read-based, assembly-based, binning, genome...
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Akkermansia muciniphila is a promising target for managing obesity and type 2 diabetes However, this randomized trial reveals that the metabolic benefits of A. muciniphila supplementation could depend on its baseline intestinal levels: https://t.co/EyWHJDHvLP
cell.com
Zhang et al. uncover that A. muciniphila-WST01 supplementation effectively colonizes and improves metabolism in patients with overweight/obese T2D with low baseline A. muciniphila. Mice with low...
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