Barriga Lab
@Mech_Morph_Lab
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We study the molecular and biophysical mechanisms underlying tissue morphogenesis @PoLDresden @tudresden_de @ERC_Research @EMBO_YIP
Arnoldstraße 18, 01307 Dresden
Joined March 2020
Our work on the role of endogenous electric fields in guiding collective cell migration in vivo is finally out @NatureMaterials ! https://t.co/UVEMt5ZGdl Congrats to all the authors, specially Fernando and @Sofia__Moreira from my lab #bioelectrics #devbio #cellmigration #xenopus
nature.com
Nature Materials - Electric fields guide collective cell migration in developing embryos of Xenopus laevis via a voltage-sensitive phosphatase.
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Great opportunity here!!
🚨 #WeAreHiring! Wir beim Physics of Life suchen für ein/e Verwaltungsleiter/in für unser internationales Team. 🌍 Wir freuen uns auf Ihre Bewerbung! 🗓️Frist: 30.10.2025 Alle Details hier: https://t.co/HhjPN7cJ3I
#sachsenjobs #jobalert #admin #dresdenjobs #jobstelle
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Our next extraordinary biologist is Mark Peifer, recent @Co_Biologists Director and a prolific author, having published in @Dev_journal, @J_Cell_Sci and @BiologyOpen. #100biologists
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Grateful for the support from @ERC_Research @EMBO @dfg_public @tudresden_de & @PoLDresden also thanks @JMarcetteau for the illustrations and referees for their comments. Congrats to Custodio!
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We also highlight our recent discovery about electrosensing: Voltage-Sensitive Phosphatase 1 (VSP1) acts as an electrosensor during electrotaxis, guiding migrating cells under endogenous electric fields in vivo. #VSP1 #Electrotaxis
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For years, limited data, forceful approaches & over-interpretations made non-neural bioelectricity seem like fiction. Nonetheless, in this review, we discuss several studies showing how bioelectricity integrates with molecular & cellular programs to influence morphogenesis.
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New Review! #devbiol #bioelectricity #CellBiology #tissueregeneration In our new @AnnualReviews piece, we explore how bioelectricity is generated, sensed & translated into responses that sculpt tissues, guide growth & enable tissue regeneration.
annualreviews.org
Bioelectricity is likely as old as life itself. From the moment the first proto-cell was enclosed in a lipid bilayer, a membrane potential arose. Thus, one can expect that bioelectrical activities...
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It's finally here! Welcome to #mbiosys25! We are excited to kick off the meeting today in beautiful Puerto Varas, Chile, with colleagues from across Latin America and beyond 🌎✨ Four days of science, community, and collaboration ahead! #unubiolac2025
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ongratulations to all co-authors! Thanks to our funders @ERC_Research @EMBO @FundlaCaixa @dfg_public and our previous hosts @FCGulbenkian and of course @PoLDresden and to the amazing @Xenbase and 🐸🐸community. the full text is here:
biorxiv.org
Epimorphic regeneration encompasses several stages, such as wound healing, formation of a regenerative bud and regenerative outgrowth. The signatures that define each stage have been well studied,...
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Good resource here…
🧵1/14 Preprint thread! Can we predict a cell’s fate based on its dynamics? 🔮 Our new study unveils a framework for watching development unfold in real-time, revealing how a cell's shape and movement encode info about its future fate. 🔬📄 Preprint: https://t.co/84lDgRTJgc
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Finally, our work reveals a hidden mechanical state of regeneration where tissue stiffening instruct cells to transit into regenerative states... Far from perfect but always looking forward to hearing from you #Regeneration #Mechanobiology #Piezo1 #Yap1 #Xenopus #FrogPower
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... for me the most striking result was that by activating this mechanosensitive cascade in NON-regenerative stages was sufficient to reactivate regenerative programs and induce di novo regeneration of full tails...!
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Are you interested on how regenerating tissues transit between stages? Am sharing here our work showing that during #Xenopus tail regeneration, tissue stiffening activates a Piezo1-Yap1 mechanosensitive cascade to allow wounded epithelia to transit into regenerative states!
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El próximo martes 23 de septiembre ya sale a la venta la reedición de mi libro de divulgación científica sobre edición genética y herramientas #CRISPR #EditandoGenes publicado por @pinolialibros es una edición revisada y actualizada. Con prólogo de Francis #Mojica @UA_Universidad
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Happy to share latest review from the lab: https://t.co/YVaqL3amEw. Stay tuned with our upcoming special issue on Environmental control of oogenesis and ovarian dynamics in Seminars in Cell & Dev. Biology!
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Congratulations to all awardees, @ERC_Research provides career changing awards with countless transformative impacts!
In 2025, the successful ERC Starting Grant applicants have 51 different nationalities and will carry out projects in 25 countries. This round of grants is estimated to create some 3,000 jobs within the teams of the new grantees. More facts and figures 👉 https://t.co/dVRIGSyi5T
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New preprint! 🚨 We uncover a slow adaptation to stretch that links star-bundling of keratin filaments with nuclear escape from its keratin cage. Led by @tom_golde 🙌 @IBECBarcelona
https://t.co/HZVLYVkcde
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