FranzeLab 🇺🇦
@Franze_Lab
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We investigate how mechanical interactions between neurons and their environment contribute to CNS development and disorder. @Cambridge_Uni @MPZ_PhysMed @UniFAU
Erlangen, Germany
Joined September 2016
You fully deserve it! Just continue your amazing research at the interface of physical and life sciences. very much looking forward to future breakthroughs coming from your lab!
@EMBO @ERC_Research @dfg_public @tudresden_de and of course! Big and special thanks to @Franze_Lab for the continued support and this nomination 🙏🏼🐸
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Highly recommended, great lab! And even if I may be a bit biased, I think the environment is also cool. #mechanobiology #MPZPM
We are looking for: PhD Student (starting as Research Assistant) and Postdoctoral Researcher in Stem Cell Biology and Mechanobiology. Please RT💕 🔗 About our lab: https://t.co/53gtr8qx68 🎓 PhD position: https://t.co/hL3Zfk7oII 🧪 Postdoc position: https://t.co/0mVS4ZaomG
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We will miss you badly, my friend...
Jochen Guck just passed away. He was not only a brilliant mind, amazing researcher, and outstanding person — he was also one of the best friends one could ever have. Jochen, you will be missed so deeply. Your spirit and laughter will stay in our hearts forever.
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Thanks @DionnHargreaves @LabWoolner @Dev_journal for highlighting our preprint! Curious how mechanical and chemical signaling guide axon pathfinding—or how frogs are an excellent model for unpicking this question?@Franze_Lab @EvaPillai 🐸🧠 Check it out. #xenopus #Devbio
In preprints: unpicking chemical and mechanical crosstalk for axonal pathfinding @DionnHargreaves and @LabWoolner discuss the #preprint from @EvaPillai, @SudiptaM1994, @Franze_Lab et al. https://t.co/Cpy8AGww2n
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Thanks a lot for choosing our preprint and for the very nice prelight!
In preprints: unpicking chemical and mechanical crosstalk for axonal pathfinding @DionnHargreaves and @LabWoolner discuss the #preprint from @EvaPillai, @SudiptaM1994, @Franze_Lab et al. https://t.co/Cpy8AGww2n
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Susie’s paper is online! Great collaboration with @Franze_Lab , Shi-Lei and @EdouardHannezo
Online now: Differential tissue deformability underlies fluid pressure-driven shape divergence of the avian embryonic brain and spinal cord
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hey science friends, in case you didnt already know, everyone is over at the blue place. come on over, its hoppin'!
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Also going towards a bluer sky 🦋🔵 Please, maintain your handle as in Twitter (X) so that I can meet you again 💙 https://t.co/VISRFsVgYE
wikihow.com
Seamlessly move from Twitter to Bluesky with this handy guide If you're migrating from Twitter/X to Bluesky, the new platform can feel lonely until you find people to follow. Fortunately, there are...
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Join us @Roche's Institute of Human Biology (IHB) as a Scientific Group Leader! Lead innovative research in #HumanModelSystems such as #Organoids. We especially seek applications aligned to our commitment to diversity and inclusion. More https://t.co/3uVStARGPR #TeamIHB #pRED
institutehumanbiology.com
Careers Institute of Human Biology (IHB) The Institute of Human Biology (IHB) is a new research center located in Basel Switzerland dedicated to engineering the most advanced human model systems for...
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🚨 Job Alert! Please RT 🙏 Fully-funded postdoc positions (4+2 years) available! Join the dynamic, collaborative community @TheCrick with access to top-tier technology platforms and an outstanding postdoc training program. https://t.co/03Y79cXm0P
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Please RT: Job alert! We have a vacancy for a technician to be in charge of our microscopes (AFM..), with the possibility of permanent employment! You love microscopy and enjoy working in a dynamic international team @MPZ_PhysMed @UniFAU ? Then apply here:
academics.com
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This course changes lives. If you are serious about a career in #devbiol, you should apply! Generous fellowships are available so don’t be shy, apply!!!
Embryology: Concepts and Techniques in Modern Developmental Biology 🧫 🧬 🔬 🦠 June 1 – July 15, 2025 Deadline: January 22, 2025 https://t.co/bXXfJNMlQ6
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And it is out! Check out the new story of the lab that shows how nuclear deformabiliy influences their movements…and when… https://t.co/pXdH3uJosh
cell.com
Maia-Gil et al. probe how nuclear properties affect apical nuclear migration in zebrafish neuroepithelia. Overexpressing lamin A stiffens nuclei, impairing migration. Further, control nuclei in a...
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in vivo optogenetic control of actomyosin contractility deep within the zebrafish brain
Now that we have polished it a bit, we are excited to share our new preprint with you "Local optogenetic NMYII activation within the zebrafish neural rod results in long range, asymmetric force propagation"
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Cool work here…!
Excited to share our latest work on an image analysis paradigm that combines cell state and morphology analyses of patient biopsies at single cell resolution to uncover clinically relevant head-and-neck #cancer phenotypes! @CellCellPress
https://t.co/ijdKjiwHXl tweetorial👇
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Frog job alert!
Hey #Xenopus enthusiasts, my lab at Pitt is looking to recruit a Ph.D. student through our Ecology and Evolutionary Biology Program to continue our work on how allotetraploidy has shaped gene expression during early development! Please spread the word! @frogwranglers
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🚨 Super psyched this story is finally out! Herculean effort and 3rd chef d’oeuvre in @NatCellBio by @patriziaromani in just 5y, where we describe #mitochondrial #mechanotransduction. https://t.co/l9oRSFdhaH Megathread with bonuses ⬇︎⬇︎⬇︎
nature.com
Nature Cell Biology - Romani et al. show that matrix stiffness, confinement and applied forces impact mitochondrial dynamics and DRP1- and MIEF1-dependent mitochondrial fission regulates...
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5. a lot still on the table: - the MIEF1 kinase - how phosphorylation affects fission - what other mitochondrial functions - how mitochondrial length regulates tx factors - relevance for physiology and disease Work with us to develop these projects!
jobrxiv.org
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Check out our new preprint where we show that cell shape noise facilitates shape transitions! It was a heroic project led by @WolframPonisch (theory) and @IskraYanakieva (experiments) and a great collaboration with @GSalbreux Summary in Wolfram’s thread https://t.co/3OHnB1LD4a
biorxiv.org
Cellular shape is intimately linked to cell function and state, and transitions between cell states are tightly coupled to shape changes. Yet, shape has been largely overlooked in state transitions...
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