Mancias Lab
@ManciasLab
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#PancreaticCancer Research Lab interested in selective #autophagy, iron, therapeutic resistance, and #proteomics. @DanaFarber, @BrighamWomens, @harvardmed
Boston, MA
Joined May 2017
The Mancias Lab @DanaFarber is fighting #PancreaticCancer on #WorldPancreaticCancerDay #WPCD2017 #WPCD #PANCaware #DemandBetter @PanCAN
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RT @SantanaCodina: Excited to share our latest story @NatureComms. Here, we used quantitative proteomics, metabolomics and in vitro/in vivo….
nature.com
Nature Communications - Pharmacologic inhibition of dihydroorotate dehydrogenase (DHODH) shows limited efficacy in pancreatic ductal adenocarcinoma (PDAC) models. Here the authors find that...
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RT @iDikic2: How #autophagy influences the regulation of MHC-I class receptors and regulates #immune evasion of #cancer?.A new role for an….
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RT @AACR: During the keynote addresses at #AACRpan24, Eileen M. O’Reilly and Joseph D. Mancias discussed how understanding pancreatic cance….
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RT @AACR: Joseph D. Mancias discussed "Targeting Autophagy in Pancreatic Cancer" in a Rising Star Keynote Lecture during the AACR Special C….
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RT @Aiims1742: The (almost) full program is now online with an amazing lineup of speakers! .#AACRPan24.@EileenMOReilly @ManciasLab @DrJashD….
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RT @rushika_perera: #AACRpan23 @graceah9 presenting her poster today - an awesome collaboration with @ManciasLab
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RT @SantanaCodina: WE ARE HIRING! We are looking for a motivated postdoc to work on a fully-funded project studying the role of iron metabo….
au.dk
Ledig stilling ved Institut for Biomedicin - Forskning og uddannelse, Syd, Aarhus Universitet
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RT @Aiims1742: Our #OpenAccess review on #PancreaticCancer - advances & challenges is now online at @CellCellPress .Many thanks to @CJHPhD….
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RT @LGlimcherMD: We are so inspired by patients like Candace and her experience. With a loving and supportive family and the latest treatme….
blog.dana-farber.org
Published: February 6, 2023Written by: Saul WisniaAfter losing her first husband of 30 years to cancer, Candace “Candy” Langford felt blessed to find love again. And when she learned six weeks after...
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RT @LGlimcherMD: Researchers at @DanaFarber and other institutions recently made important discoveries into the recycling system of pancrea….
blog.dana-farber.org
Published: December 28, 2022Updated: December 29, 2022Written by: Rob LevyMedically Reviewed By: Joseph D. Mancias, MD, PhDPancreatic cancer cells operate a recycling program that would be the envy...
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RT @DanaFarber: Pancreatic cancer cells operate a recycling program that would be the envy of any municipality — but the only beneficiaries….
blog.dana-farber.org
Published: December 28, 2022Updated: December 29, 2022Written by: Rob LevyMedically Reviewed By: Joseph D. Mancias, MD, PhDPancreatic cancer cells operate a recycling program that would be the envy...
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RT @DamonRunyon: A cross-country collaboration between former Damon Runyon-Rachleff Innovators @rushika_perera and @ManciasLab uncovered an….
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RT @jonathan_nowak: Latest Wolpin-Nowak lab paper on single cell, in situ protein-based characterization of transcriptional subtypes in pan….
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RT @ElizSMcKenna: Now online in @CD_AACR: Targeting UGCG Overcomes Resistance to Lysosomal #Autophagy Inhibition by Vaibhav Jain, David Spe….
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RT @DanaFarber_Hale: Robert Hale's determination in @DanaFarber and the Hale Family's incredible generosity help drive @DanaFarber_Hale clo….
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RT @rushika_perera: On the cover!! Thanks @CD_AACR for featuring work from our lab by Miru Ravichandran and @ManciasLab @SantanaCodina on t….
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RT @SantanaCodina: Thanks to @CD_AACR for featuring our stories @ManciasLab and @rushika_perera on the cover of the September issue!.
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RT @LyssiotisLab: 🚨Job Posting: The @YatrikShahLab & @LyssiotisLab are looking for a postdoc to study the role of iron, O2, & metabolism in….
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RT @NatRevClinOncol: Two recent preclinical studies highlight the importance of ferritinophagy in pancreatic cancer, with elevation of a fe….
aacrjournals.org
Interplay between MiT/TFE and c-MYC transcription factors fine-tune autophagy and lysosome biogenesis to promote increased ferritin degradation and iron supply, which fuel increased mitochondrial...
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