Mara Sherman Lab
@MaraShermanLab
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Cancer biologist @MSKCancerCenter
New York, NY
Joined November 2018
RT @whitefishlab: A new Research Briefing is out about Miranda's paper. Check it out here:
nature.com
Nature - The switch between proliferation and invasion is triggered by mechanical force.
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RT @obenaufa: Exciting FULL PROFESSORSHIP in Vienna at the Vienna BioCenter - Molecular Mechanisms of Disease Mechanisms: .
maxperutzlabs.ac.at
The Max Perutz Labs - one of Europe’s leading institutes for basic research in the life sciences - invite applications for a Full Professorship in Molecular Mechanisms of Disease. We are seeking...
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The most fun image & video creation tool in the world is here. Try it for free in the Grok App.
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RT @LyssiotisLab: 🫵🏼 Join our awesome Dept (@UMPhysiology)! This faculty search has a GI lean, backed by a super strong departmental emphas….
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Check out this beautiful new study by Miranda Hunter, @whitefishlab & team linking mechanical force to phenotype switching and tx resistance in melanoma. And the brilliant 1st author is on the job market! 🐟✨
nature.com
Nature - Mechanical confinement of cancer cells at the tumour–microenvironment interface induces phenotype switching through chromatin remodelling by HMGB2, leading to a more invasive and...
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RT @DLawsonlab: Check out our new paper identifying the developmental gene PHLDA2 as a robust driver of breast cancer metastasis! Thanks to….
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RT @lydfinley: Applications are open for early-career researchers to attend our workshop on “Revisiting Metabolic Fundamentals” April 26-29….
biologists.com
Revisiting Metabolic Fundamentals This Workshop will bring together a diverse group of scientists whose work challenges and redefines traditional views of metabolism, for example uncovering new...
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2 billion wows - transformative generosity at such a critical time for cancer research. Congrats to the whole OHSU Knight community!.
Phil and Penny Knight announced today a record-breaking $2 billion gift to the Oregon Health & Science University’s Knight Cancer Institute to transform the future of cancer care and set a new standard globally. Thank you to Phil and Penny Knight for their incredible generosity.
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Interested in the dynamics of cancer progression and persistence? Please join me, Mariam, Ken, and our fantastic speakers in Albuquerque this Dec to discuss diverse features of cancer evolution! 🧩🔎🦀.
Submit an abstract by October 1 for the AACR Special Conference on Cancer Evolution (December 4-6; Albuquerque), chaired by Mariam Jamal-Hanjani, Kenneth J. Pienta, and Mara H. Sherman and held in association with #AACRCEWG. #AACRevol25 @MaraShermanLab
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RT @thenormanlab: Our paper is now out in final form at Nature Genetics! For those who missed the preprint, we used large-scale Perturb-seq….
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Big congrats to @ErnstLengyel and team for this beautiful study linking NNMT in fibroblasts to suppression of antitumor immunity! And exciting results in preclinical models of ovarian cancer 👏🏻👏🏻.
🔥 Hot off the press: In a new @Nature study, @ErnstLengyel and team show that blocking NNMT in tumor-supporting cells restores immune response & stops ovarian cancer growth, offering a new strategy for hard to treat cancers. @OvCa_UChicago @uchicago_obgyn.
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RT @Aiims1742: A jobs bonanza from @michiganstateu @HenryFordHealth hiring TEN cancer researchers! .Applicants focu….
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RT @Mayr_Christine: More than 2700 3′UTRs are highly conserved. These 3′UTRs are essential components in mRNA templates, as their deletion….
biorxiv.org
More than 2,700 human mRNA 3′UTRs have hundreds of highly conserved (HC) nucleotides, but their biological roles are unclear. Here, we show that mRNAs with HC 3′UTRs mostly encode proteins with long...
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RT @ChiaraFalcomata: 🚨 Our new #preprint is out!.We used #PerturbMap spatial functional genomics in pancreatic canc….
biorxiv.org
Pancreatic ductal adenocarcinoma (PDAC) is characterized by a dense extracellular matrix (ECM) that sustains an immunosuppressive tumor microenvironment (TME). While this protective niche has been...
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RT @PitarresiLab: I'm excited to share the lab’s new paper on PDAC-associated cachexia on bioRxiv today, led by star postdoc @Nikita2106. P….
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Congratulations to @shouval and all authors for this beautiful and suuuper nicely done study showing a new (and perhaps targetable) way CAFs suppress anti-tumor immunity in breast cancer! 🤩.
Thank you @MaraShermanLab for this insightful spotlight on our recent paper in @CD_AACR !.Love the title too 😍 - CAFs Defang NK Cells to Promote Breast Cancer Immunosuppression
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Behold! From the latest badassery out of the amazing Perera lab, we learn that cholesterol uptake patterns dictate where pancreatic cancer cells seed and grow in the body. Congrats all!! 🤩.
Online today in @Nature - our latest study led by superstar postdoc @GillesRademaker detailing the role of PSCK9 in driving sterol dependent metastatic organ choice in pancreatic cancer full text available here 👉 and thread 👇.
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RT @CD_AACR: In the Spotlight: FABP4-tastic Pancreatic Stellate Cells Coddle KITL to Uphold Inherent Microenvironmental Tumor Suppression h….
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RT @DrAriaV: I am thrilled to share that the first preprint from my lab is now available on bioRxiV! In this study, our team elucidates the….
biorxiv.org
Secretion of ligands of the human epidermal growth factor (EGFR) family of receptors or erythroblastic leukemia viral oncogene family (ERBB1-4) is a feature common to many cancer cells. However, our...
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RT @deVisserKarin: Very excited that our paper on how breast cancer impacts granulopoieses is @Cancer_Cell Fantastic teamwork with the lab….
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RT @ednacukierman: Yes! This is another @CD_AACR seminal study by the amazing @MaraShermanLab @MSKCancerCenter and her terrific team & coll….
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