NatureRevClinOncol
@NatRevClinOncol
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The latest clinical diagnostic, treatment & personalized medicine advances & more from Nature Reviews Clinical Oncology, a reviews journal.
London, UK
Joined August 2011
New online! Treatment of NSCLC after chemoimmunotherapy — are we making headway?
nature.com
Nature Reviews Clinical Oncology - Immune-checkpoint inhibitors have dramatically improved the outcomes in patients with advanced-stage driver-negative non-small-cell lung cancer (NSCLC), although...
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New online! Cured but breathless: the growing burden of DIILD in cancer survivors
nature.com
Nature Reviews Clinical Oncology - Drug-induced interstitial lung disease (DIILD) is emerging as a hidden toll of modern oncology. Diagnosis of DIILD is confounded by non-specific symptoms and the...
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New online! SERENA-6: dynamic ctDNA assessment and the future of precision cancer medicine
nature.com
Nature Reviews Clinical Oncology - The SERENA-6 trial assessed a paradigm-shifting approach to personalized cancer therapy in patients with advanced-stage breast cancer, in which therapy was...
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New online! Surprising role of CMV in shaping outcomes of immunotherapy for melanoma — chronic infection yields favourable survival
nature.com
Nature Reviews Clinical Oncology - Recent clinical data indicate that infection with the common β-herpesvirus cytomegalovirus (CMV) confers beneficial effects on the T cell compartment that...
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New online! Rethinking cancer of unknown primary: from diagnostic challenge to targeted treatment
nature.com
Nature Reviews Clinical Oncology - Cancer of unknown primary (CUP) constitutes a diagnostic quandary and has a dismal prognosis, with standard empirical chemotherapy providing limited benefit. This...
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New online! Understanding and overcoming multidrug resistance in cancer
nature.com
Nature Reviews Clinical Oncology - Despite advances in cancer therapy, the persistent challenge of treatment resistance and particularly multidrug resistance remains a substantial barrier to...
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New online! Clarifying the role of SONIA: supporting academic evidence on CDK4/6 inhibitor timing
nature.com
Nature Reviews Clinical Oncology - Clarifying the role of SONIA: supporting academic evidence on CDK4/6 inhibitor timing
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New online! EMT and cancer: what clinicians should know
nature.com
Nature Reviews Clinical Oncology - Despite several decades of research that has revealed roles in the development and progression of many solid tumours, clinical translation of research targeting...
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New online! PROTAC SERD vepdegestrant outperforms fulvestrant for advanced-stage ER+HER2− breast cancer harbouring acquired ESR1 mutations
nature.com
Nature Reviews Clinical Oncology - Next-generation, oral selective oestrogen receptor degraders (SERDs) have been shown to improve outcomes in patients with advanced-stage oestrogen receptor...
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New online! Evolving roles of MET as a therapeutic target in NSCLC and beyond
nature.com
Nature Reviews Clinical Oncology - MET mutations, amplifications and fusions and MET overexpression are promising therapeutic targets across various cancers. In this Review, the authors summarize...
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New online! The microbiota in radiotherapy-induced cancer immunosurveillance
nature.com
Nature Reviews Clinical Oncology - Radiotherapy has an established role in the treatment of many patients with cancer, with evidence suggesting that this modality can also have immunostimulatory...
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New online! Therapeutic targeting of mismatch repair-deficient cancers
nature.com
Nature Reviews Clinical Oncology - This comprehensive Review describes the biological function of the mismatch repair (MMR) machinery, the genomic sequelae of defects in this machinery and the...
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New online! EHA–EMN Evidence-Based Guidelines for diagnosis, treatment and follow-up of patients with multiple myeloma
nature.com
Nature Reviews Clinical Oncology - In these Evidence-Based Guidelines, a multidisciplinary panel of experts from the European Hematology Association and the European Myeloma Network provide key...
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New online! Perioperative pembrolizumab demonstrates clinical benefit in locally advanced HNSCC
nature.com
Nature Reviews Clinical Oncology - Perioperative pembrolizumab demonstrates clinical benefit in locally advanced HNSCC
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New online! A new first-line option for advanced-stage anal squamous cell carcinoma
nature.com
Nature Reviews Clinical Oncology - A new first-line option for advanced-stage anal squamous cell carcinoma
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New online! Role of novel immunotherapy combinations in the management of advanced-stage hepatocellular carcinoma
nature.com
Nature Reviews Clinical Oncology - Immune-checkpoint inhibitors have revolutionized the management of hepatocellular carcinoma. Currently, anti-PD-(L)-1 antibodies combined with either bevacizumab...
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New online! Ecological management of the microbiota in patients with cancer
nature.com
Nature Reviews Clinical Oncology - This Review synthesizes the current understanding of host–microbiota dynamics in patients with cancer and proposes to integrate microbiota management...
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New online! Zanidatamab shows promise as first-line therapy for advanced-stage HER2+ GEA
nature.com
Nature Reviews Clinical Oncology - Zanidatamab shows promise as first-line therapy for advanced-stage HER2+ GEA
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New online! Second-line tarlatamab improves OS in SCLC
nature.com
Nature Reviews Clinical Oncology - Second-line tarlatamab improves OS in SCLC
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