Dept. of Molecular Biology, MGH
@MGHMolBio
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@MassGeneralNews, Members of @MGH_RI, Faculty from @BBS_Harvard @HarvardGSAS @HarvardMed @HMSGenetics @broadinstitute
Boston, MA
Joined May 2018
RT @harvardmed: Nobel Laureate and HMS Professor Gary Ruvkun shared lighthearted tales about his start, a science revolution, and the power….
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RT @Dev_journal: Manipulating cell fate through reprogramming: approaches and applications. Read this Primer from Masaki Yagi, Joy Horng an….
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RT @TheXavierLab: (1/3) This important collab with @WangXiaoLab, out now in @NatureBiotech, promises to expand the potential of mRNA-based….
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RT @XistHarvard: Re-analysis of CLAP data affirms PRC2 as an RNA binding protein and XIST RNA as a target. We (YongWoo Lee, Roy Blum, Mich….
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RT @MGH_RI: Researchers from @MGHMolBio and colleagues published the paper, small-molecule probe for IBD risk variant GPR65 I231L alters cy….
science.org
Structure-activity relationship study identifies small molecules that induce signaling in autoimmunity risk variant GPR65 I231L.
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RT @NiekampStefan: Very excited to see our work on PRC1 and chromatin condensation online @MolecularCell I am grate….
cell.com
Through reconstitution and imaging, Niekamp et al. reveal that the Polycomb repressive complex 1 (PRC1) and chromatin act synergistically to form condensates. They show that specific combinations of...
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RT @DMSHarvard: TODAY: at 2:00 PM EDT, Aleksandar Radakovic (BBS) defends his dissertation "Primordial role for RNA aminoacylation in the a….
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RT @TheXavierLab: @mrtbrandt and colleagues at @broadinstitute @MGHMolBio @MGH_RI applied translational genetics to a rare CARD9 missense v….
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RT @MGH_RI: In a recent @MolecularCell publication, researchers from @MGHMolBio and colleagues discovered new insights into the silencing o….
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RT @MWalkerMDPhD: Continuing our study of the somatic segregation of pathogenic mitochondrial DNA variants. T cell activation selects again….
pubmed.ncbi.nlm.nih.gov
T cells have been shown to maintain a lower percentage (heteroplasmy) of the pathogenic m.3243A>G variant (MT-TL1, associated with maternally inherited diabetes and deafness [MIDD] and mitochondrial...
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RT @VamsiMootha: Leveraging our discovery of markers of mitochondrial disease, our collaborative team @MassGenBrigham now reports plasma N-….
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RT @XistHarvard: Imprinted X-chromosome inactivation through inherited silencing of the oldest genes -- Check it out here! And congrats to….
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RT @MGH_RI: Researchers from @MGHMolBio and colleagues investigate cellular pathogenesis in Friedrich's ataxia, in a @MolecularCell study.….
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RT @the_Node: Meet #theNodeCorrespondents—Shreyasi Mukherjee. In this interview, @_smukherjee, a postdoc @MGHMolBio @harvardmed, talks abou….
thenode.biologists.com
Find out more about our new correspondent, Shreyasi Mukherjee, a postdoc at Massachusetts General Hospital and Harvard Medical School.
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RT @MGH_RI: Researchers from @MGHMolBio and colleagues investigate hypoxia-driven rescue of mitochondrial disease, in a @CellCellPress stud….
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Latest from the Hung group and colleagues:. Genetic factors affecting storage and utilization of lipids during dormancy in Mycobacterium tuberculosis | mBio
journals.asm.org
Tuberculosis is a global threat, with ~10 million yearly active cases. Many more people, however, live with “latent” infection, where Mycobacterium tuberculosis survives in a non-replicative form....
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RT @VamsiMootha: Hypoxia rescue (& hyperoxia sensitivity) of mito CI mutants is evolutionary conserved! Harnessing the power of worm geneti….
cell.com
C. elegans mutants harboring a defective mitochondrial complex I are rescued by hypoxia or intra-complex genetic suppressor mutation, achieved by increasing forward flow of electrons through complex...
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RT @VamsiMootha: Delighted to share new study by Tslil Ast now @WeizmannScience w/ Y. Itoh, D. Suess, @A_Amunts showing (1) the Fe-S proteo….
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RT @FMCBenning: How do baculoviruses protect their genome?. Delighted to present our findings in print!. We use cryo-EM to determine the st….
nature.com
Nature Communications - Baculoviruses are used as insecticides, gene therapy tools, and protein production vectors. Here, the authors report the structure of the Autographa californica MNPV...
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