OMA-1 is a zinc finger RNA-binding protein required for oocyte maturation. This work identifies an arginine-rich peptide upstream of the zinc finger required for both RNA binding and embryogenesis. https://t.co/ke616Rh0cV

The absence of an inductive effect confers pseudouridine residues with resistance to enzyme-catalyzed and spontaneous strand cleavage. https://t.co/m3LywpEN9z

PACT suppresses PKR activation, thus preventing activation of the integrated stress response, NF-κB, and cell death. Dimerization and double-stranded #RNA binding by PACT is required for this function. https://t.co/bW5MoeI3P7 @KyleCottrell @PurdueBiochem @PUCancerInst

Spatiotemporal NAIL-MS analysis shows that ALKBH5 does not affect global m6A turnover in human mRNA across subcellular compartments under standard growth conditions. https://t.co/s1QjOExxnd

An internal 8U tract in a recoded influenza A virus segment causes viral polymerase slippage.  This in turn leads to truncated protein production, interferon stimulation and reduced virus production. https://t.co/jeGoXwkhQ3

FBF-1 RNA binding is not regulated by its C-terminal tail (CT), whereas highly similar FBF-2 is inhibited by its essential CT. Partner protein competes with CT binding to regulate FBF-2 but not FBF-1. https://t.co/P1qoPuNKK2

We present a method to profile RNA within membrane-less organelles, utilizing in situ transcription and linear amplification. We substantiate the accumulation of immature pre-mRNAs in stress granules. https://t.co/dfSp37sMtB

Two-step VEGF HDB recognition by an aptamer, t44.27, was unveiled. Transient interaction was followed by a tight-complex formation and latter of which is essential to antagonize heparin binding. https://t.co/U3x2LtaAIG

Coevolution of protein-only RNase P and tRNA genes in Aquifex aeolicus: most precursor tRNAs have an A residue upstream of the 5’-cleavage site and generally lack stable acceptor stem extensions. https://t.co/0wlueCfT6j

In silico λ-dynamics accurately predicts interactions of modified RNA to a model RNA-binding protein. The work opens opportunities to study modified RNA-protein interactions without in vitro reagents. https://t.co/sqwvLyYxge

Translational helicases eIF4A, Ded1 and Slh1 are found to be dispensable for mRNA scanning in search of the start codon by 40S ribosomes. Instead, mRNA scanning is driven by one-dimensional diffusion. https://t.co/k9zMtbjtS9

Visualization of full-length 7SK and 7SL RNAs tertiary atomistic models derived using small-angle x-ray scattering, coarse-grained modelling, and molecular dynamics simulations. https://t.co/IPQtK4jvPB

Stress granules elevate p21 RNA levels and reduce Rb phosphorylation, promoting cell cycle exit. https://t.co/clmirQv4VD

Rampant A-to-I RNA editing in Drosophila lncRNA roX1 is non-adaptive and does not provide a selective advantage to the organism. https://t.co/9de1AV13mt

Eukaryotic translation initiation factors (eIFs) 5 and 2B compete for eIF2. The three binding sites on eIF2β (K1, K2, and K3) allow simultaneous binding and faster mutual displacement from eIF2γ. https://t.co/psIae16PzH

DNA plasmid constructs were used to produce dsRNA via in vivo transcription within E. coli, or via in vitro transcription. Analysis was performed to quantify the dsRNA produced and measure dsRNA product quality. #dsRNA #T7Polyermase @sheffielduni https://t.co/BpAgz9IDme

RNA modifications in T cells are more stable than expected—primary and immortalized cells share most sites, suggesting common regulatory features can be studied across systems. https://t.co/VJKaVJKNcL

M6A methylation of the Dand5 3’UTR blocks Bicc1 binding, suggesting it may limit the silencing and/or decay of this and potentially other mRNAs that is induced by flow-sensing cilia. https://t.co/gCFsZacnSq

U7 snRNA binds a ring of seven proteins, including Lsm10 and Lsm11, forming U7 snRNP core. This report identifies 3 proteins (blue) that interact with U7 snRNA and may participate in the assembly of this unusual and functionally critical ring. https://t.co/Y5H2VrdFEJ

Free tRNALeu shows flexible variable arm and CCA end, reshaped by LeuRS and ribosome binding. #tRNA #StructuralBiology @RNAJournal @GIST_science https://t.co/jTUbSjj1Eg