This month, I officially started as an Assistant Professor at @UCSanDiego. I’m thrilled to join the Department of Physics @UCSDPhysics and the Department of Chemistry & Biochemistry in @UCSDPhySci. I’m especially excited to be part of the UCSD Biophysics faculty - a unique place

🚨 We are hiring a #postdoc in Quantitative Cell Biology/Biochemistry. Join us if you are interested in using super-resolution STED & cryoET to uncover self-organization dynamics of epithelial cell interfaces & glycobiology collaboration with WuLab https://t.co/NsZS1X7iPo

Congratulations Anita on a beautiful paper!!! Using artificial intelligence to smell (and functionally dissect) the nucleolar flowers :)

☁️bonus @squidgame themed fun graphical abstract #오징어게임

Grateful to @NIH for their support 🙏 We’re looking for PhD students & postdocs excited about nonlinear dynamics and physics of living systems. Come join us—and please help spread the word!

Chromatin heterogeneity modulates nuclear condensate dynamics and phase behavior. Congratulations Jing! Happy to have contributed in a small way to this interesting work! https://t.co/OZHRknyFV4

Go Amy!!!!!

Our tour de force into the nucleolar world — a stunning exploration of spatial organization and the functional choreography of ribosome biogenesis now out in Nature✨ https://t.co/eZdIYTFyBk Led by @sofiquinodoz, @jiang_lifei, @brangwynnelab, with theory partners @QiweiYu2,

Excited that our nucleolus mapping paper just came out today in Nature! Truly an amazing study from even more amazing due of @sofiquinodoz & @jiang_lifei w/ @LafontaineLab & Sebastian Klinge and other fantastic co-authors

So happy to see our work officially out today @Nature on how ribosome biogenesis shapes the multiphase architecture of the nucleolus! Truly grateful to have worked so closely with @sofiquinodoz @brangwynnelab and all the coauthors.

Awesome paper alert! Learn about spectrum of chromatin condensate morphologies due to elastocapillary effects (no, liquids do not need to be spherical!), from amazing @DNAmyStrom & Hongbo Zhao, w/ important contributions from co-authors Eeftens, Haataja, Kosmrlj.

Coupling with reaction-diffusion, we can also do "optogenetic experiments" with these simulations -- local activation of wetting or nonwetting condensates locally recruit or exclude chromatin.

We can also do shearing on the condensate-network complex. We find that wetting condensates can induce stiffening by an order of magnitude compared to a dry network (i.e. in a pure solvent with no condensates), with implications on interactions between wetting and nonwetting

Of course we show that our method is identical to the well-known and classical results of elastocapillarity between a single fiber and condensates

We also systematically studied the interplay between elasticity and capillarity in this phase diagram: when capillary forces overcome elastic forces of the network, droplets become larger, otherwise droplets are confined to pores in the network.

Another joyful and unparalleled collaboration with the amazing @DNAmyStrom herself during my postdoc at @brangwynnelab and Kosmrlj groups -- we developed a novel computational framework to study elastocapillary interactions between condensates and fiber networks (in this case

ODBI is seeking a scientific staff member to help run a new microscopy facility. This facility will house roughly a dozen advanced light microscopes, with a particular focus on light microscopy approaches for both imaging and active interfacing with living cells and organisms.