Roberto Zoncu
@RobertoZoncu
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Professor of Molecular & Cell Biology @ UC Berkeley https://t.co/I4b96kPzRj
San Francisco, CA
Joined July 2018
Excited to showcase published version of our covalent destabilizing MYC degrader in @angew_chem that stereoselectively targets an IDR C203 in MYC! Congrats to Hannah Rosen and Kelvin Li & thanks to #TomMaimone, @NovartisScience & @TheMarkFdn!
onlinelibrary.wiley.com
This study reports stereoselective sulfinyl aziridine covalent ligands that directly degrade the oncogenic transcription factor MYC by engaging intrinsically disordered cysteine C203. Lead compound...
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BAMM 2025 attendees- getting ready for the real group photo @Stanford @UCSF @UCBerkeley @StanfordDRC
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Excited to share our new preprint led by PhD student Alex Ekvik reporting a genetically encoded tool for manipulation of ATP/ADP ratio in human cells that we called ATPGobble. A 🧵... (1/6)
biorxiv.org
The ability of cells to power energy-demanding processes depends on maintaining the ATP hydrolysis reaction a billion-fold away from equilibrium. Cells respond to changes in energy state by sensing...
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If you are looking for an inspiring group of colleagues and friends, look no further than #MolecularTherapeutics at @berkeleyMCB @UCBerkeley @MTI_UCB
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congratulations Ana @apsarruda !
Congrats to MCB's Ana Arruda on being named a Pew Scholar in the Biomedical Sciences! 👏🎉
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Congrats to MCB's James Olzmann @OlzmannLab on being named a 2025 ASCB Fellow! @ASCBiology 👏🎉
Meet the 14 scientists named 2025 ASCB Fellows! Honored for excellence in research, mentorship, and service, they’ll be recognized at Cell Bio 2025 this December in Philadelphia. Read more:
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Thrilled and deeply honored to be named a 2025 Pew Biomedical Scholar! Huge congrats to my friend and colleague @CRI_UTSW @JaviGBermudez , who’s also joining the Pew family as a Pew-Stewart Scholar. CRI is on fire—let’s go make some bold, groundbreaking science happen! 🔥🧪✨
Congrats! 👏👏👏 Two CRI scientists named 2025 Pew-Stewart & Pew Scholars — @JaviGBermudez & @HijaiShin — to advance cancer, biomedical research. Read more about their #relentlessdiscovery ⬇️ https://t.co/MAFSU4zUqs
@pewtrusts
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Big congratulations to Regina @HijaiShin for this well deserved recognition, so proud of you!
22 researchers join the Pew Scholars Program in the Biomedical Sciences to investigate human health and disease. This year, scholars will explore how gut bacteria fight metabolic disease, how the human brain develops and evolves over time, and more.
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I am honored to be named a 2025 ASCB Fellow! It is a privilege to be part of the ASCB community. ASCB was the first conference I attended as a grad student, and it has always been a welcoming, supportive home. Thank you for this kind recognition! ☺️ https://t.co/sfnhbvTuJB
ascb.org
The American Society for Cell Biology (ASCB) is proud to announce the election of 14 outstanding scientists as 2025 ASCB Fellows—a prestigious honor recognizing their exceptional contributions to...
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🚀 MTI & affiliate labs at @UCBerkeley welcomed teens from @lawrencehallsci's Teen Research Program for hands‐on tours - from their first PCRs to high‐throughput compound‐screening. Big thanks to every mentor who made STEM pathways feel real! 🌟🔬#ScienceOutreach #MTI
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Our paper on discovering a new paradigm in peroxisome biogenesis and PEX39 (1st human peroxisomal biogenesis protein found in > 20 yr) is out in @NatureCellBio! Wonderful, equal collab with Tony Rodrigues, @dwendscheck, Jorge Azevedo, @warscheidlab
https://t.co/8TqgxcNqis
nature.com
Nature Cell Biology - Chen et al. show that PEX39 cooperates with PEX7 in the peroxisomal import of proteins containing a PTS2 site and uncover an (R/K)PWE motif in PEX39 and PEX13 that binds to...
V happy to share my work in @RJDLab @CRI_UTSW from past 2 yr! In equal collab with Tony Rodrigues, @dwendscheck, Jorge Azevedo’s lab, @warscheidlab, we have discovered PEX39, the first human peroxisomal biogenesis protein (peroxin/PEX) found in > 20 yr! https://t.co/uAhJ7fFeQM🧵
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🧬📈 Big win for biotech at @UCBerkeley: On July 17, 2025, the UC Regents approved the IGI-Bakar Labs building. The hub will expand lab space for the Innovative Genomics Institute - founded by MTI board member & Nobel laureate Jennifer Doudna - and build out @bakarlabs_uc - the
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Launched today- the Weill Cancer Hub West -supporting transformative cancer research collaborations btw @UCSF & @Stanford. Honored to co-lead, with @longlabstanford, our team who will study the impact of diet on pancreatic cancer initiation, progression and therapy response.
Backed by a $100M gift from Joan and Sandy Weill, UCSF and @StanfordMed @StanfordCancer are launching Weill Cancer Hub West, a $200M initiative in team science to accelerate cancer research and improve care over the next decade. https://t.co/4xTNCEmjBR
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📣 Paper alert!! Excited to share the 2nd research paper from my time in the @LabBoke at @CRGenomica, out today in the @embojournal! We asked: "how do human oocytes regulate proteostatic organelles under physiological conditions?" We collaborated with @DexeusMujer and employed
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🚨 Bay Area Biotech Day hits @UCBerkeley next week (7/22)! Hear Nobel laureate Carolyn Bertozzi + leaders from Denali, Calico, Frontier, Nurix, Arcus & more on the next wave of drug discovery. 🧬 Posters, panels & networking. #Biotech #DrugDiscovery #UCBerkeley
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Final version of our paper showing that a redundant function of several allosteric regulators of glycolytic enzymes HK and PFK is to inhibit the reaction of Harden and Young. Led by @ChoeMangyu in collaboration with Tal Einav and Rob Phillips. A 🧵... (1/)
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Hard to fathom how anyone can continue to justify the disruption of NIH research by haphazard cuts and destruction when they become aware of stories like this one related to cancer research and clinical trials.
cbsnews.com
Scientists conducting medical research are facing an existential crisis: Layoffs and budget cuts pushed by President Trump that, they say, jeopardize finding a cure for cancer.
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Exciting event coming to @berkeleyMCB @MTI_UCB !
🚀 Bay Area Biotech Day lands @UCBerkeley 7/22! Hear Nobel Laureate Carolyn Bertozzi + leaders from Denali Therapeutics, Calico Labs, Frontier Medicines & more leaders in biotechnology unveil the next wave in drug discovery. Scan the QR on the flyer to register now! 🧬🥂
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Congratulations to Elçin Ünal on her promotion to MCB Professor of Genetics, Genomics, Evolution, and Development! 👏🎉 https://t.co/Reyx5hTl7P
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