Keren Bahar Halpern
@KerenBaHa
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Assistant staff scientist at the Itzkovitz lab @WeizmannScience. Study liver heterogeneity.
Joined June 2017
Big congrats to all the recipients of the Scientific Council Prize 2021! 🙌
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Happy to share our new lab preprint: https://t.co/mlV2Uro6pg Clump sequencing exposes the spatial expression programs of intestinal secretory cells. We developed a method for reconstructing spatial expression maps of rare tissue cells.1/5
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I am very excited to announce that I am opening my lab for systems tissue pathology at @WeizmannScience ! We will use multiplexed imaging and AI to interrogate tumor-immune interactions and the tumor microenvironment, and... we are recruiting!
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Our paper on Lgr5+ villus tip telocytes just out in @NatureComms - https://t.co/WjqIJ3gdpo. We describe a localized mesenchymal cell niche that regulates enterocyte zonation.
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Excited to share our new preprint on Lgr5+ villus tip telocytes https://t.co/3p0hM5V9FR – a stromal cell that shapes epithelial cell zonation. Great work by @KerenBaHa, @HassanMassalha, @AndreasMoor in collaboration with Fred de Sauvage, @OphirKlein and Michal Shoshkes-Carmel.
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Thank you to everyone who attended the @ChanZuckerberg Seed Networks for the @humancellatlas meeting! We can’t wait to see where your projects lead #HumanCellAtlas
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Check out our new review on liver zonation with @ShaniBmo. We discuss design principles governing the spatial division of labor in the liver as well as approaches for liver spatial reconstruction.
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The transcriptional response to fasting in mice liver and muscle operates through molecular mechanisms that are distinct from time-restricted feeding regimens #Circadian
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Happy to share our new paper on beta cell heterogeneity https://t.co/sutm5E0k42. Great work from @Lydia_Farack, Matan Golan,@AdiEgozi, @KerenBaHa. (1/6)
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What cells contributed their DNA to produce “cell free DNA”? DBCR’s Yuval Dor and Ruth Shemer have the answer. Comprehensive human cell-type methylation atlas reveals origins of circulating cell-free DNA in health and disease | Nature Communications
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Reviewing a manuscript and unsure of whether the figures are colorblind-friendly. Fortunately, someone recently told me about Color Oracle, which helped me figure out that they are!
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Ladies, if he: * Solicits opinion of 3 strangers before agreeing to a date * Takes months to reply * Nitpicks about your appearance * Demands you make major changes * Won’t let you see friends unless they pay He’s not the one. He’s a scientific journal.
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In this @nature column I share the key principles I follow as a PI to make people in the @Maestrelab as happy as possible and to make my lab a nurturing & collaborative environment. If we are happy we not only work better but are more productive
nature.com
Nature - A productive lab need not be a negative environment, says Fernando T. Maestre.
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Spatial Reconstruction of Single Enterocytes | Broad Zonation along the Intestinal Villus | Shalev Itzkovitz @WeizmannScience @CellCellPress
https://t.co/w76Be0xrNt
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In order to develop the assay, you must become the assay.....
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predicting positions within tissues from sc sequencing data.
biorxiv.org
Massively multiplexed sequencing of RNA in individual cells is transforming basic and clinical life sciences. However, in standard experiments, tissues must first be dissociated. Thus, after sequen...
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Single Cell Genomics ‘18 is off & running. The theme of the morning has been spatial patterns, methods and analysis. Reminds me of an epic explanation from @LongCai_Lab in Rehovot last year about the scalability and power of spatial work - Cool to see amazing progress 1yr later.
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Hey scientists! Are your fluorescence images colour blind friendly?? 4.5% of people are #colourblind and can't see the red in your figures. Switch to magenta, yellow and cyan. Here is some inspiration 🔬
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