Nature Reviews Gastroenterology & Hepatology
@NatRevGastroHep
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We publish #gastroenterology & #hepatology Reviews and opinion. #GastroEdPick selections by the Editors: Katrina, Jordan & Eleni | #medtwitter | #sciencetwitter
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Last Seen Profiles
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Our MAY ISSUE is live! Liver glucose metabolism, bile acids and gut microbiota, dietary fibres, coeliac disease, and much more!
2
22
61
NEW! This REVIEW examines how the maternal gut
#microbiome
in pregnancy influences the developing immune system
4
145
421
0
66
273
New content online: Cholangiocarcinoma 2020: the next horizon in mechanisms and management
3
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257
New content online: Gastrointestinal and brain barriers: unlocking gates of communication across the microbiota–gut–brain axis
4
73
244
New content online: Fermented foods and gastrointestinal health: underlying mechanisms
1
79
222
From our current issue, this REVIEW describes the mechanisms of mucosal healing and how they might be altered in
#IBD
and discusses potential therapeutic approaches to promote mucosal healing and regeneration
1
77
217
New content online: Macrophages in intestinal homeostasis and inflammatory bowel disease
1
67
210
New content online: The metabolic nature of inflammatory bowel diseases
0
50
198
New content online: The maternal gut microbiome in pregnancy: implications for the developing immune system
0
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New content online: Ultra-processed foods and food additives in gut health and disease
0
67
197
New content online: The role of goblet cells and mucus in intestinal homeostasis
3
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186
New content online: The intersection between alcohol-related liver disease and nonalcoholic fatty liver disease
1
73
185
It's
#WorldMicrobiomeDay
today and this year the theme is diversity. There is certainly a diverse
#microbiota
in our guts, which can be influenced by food.
Read more in this REVIEW ->
0
82
176
Fermented foods have gained popularity owing to their health-promoting potential - this REVIEW discusses the benefits of
#fermentedfoods
in gut health and disease, and how specific microbes, food components and bioactive compounds exert their effects
2
63
153
New content online: The many means of conversation between the brain and the gut
0
46
150
New content online: Mechanisms of mucosal healing: treating inflammatory bowel disease without immunosuppression?
2
51
150
REVIEW | Early detection of pancreatic cancer using DNA-based molecular approaches
2
64
145
REVIEW |
#Metabolomics
and lipidomics in
#NAFLD
: biomarkers and non-invasive diagnostic tests
0
51
146
Various goblet cells have differing roles in the adult small and large
#intestine
, find out more in this REVIEW
0
37
147
New content online: A new era in obesity management
1
45
141
New content online: Gut feelings: mechanosensing in the gastrointestinal tract
2
30
132
REVIEW | Modern therapeutic approaches for the treatment of malignant liver tumours
0
61
128
NEW! REVIEW |
#Metabolomics
and lipidomics in
#NAFLD
: biomarkers and non-invasive diagnostic tests
#fattyliver
1
51
129
Check out this
#NatureResearch
web collection on the
#gut
-
#brain
axis. Neuroimmune,
#microbiota
& more!
#neurogastro
1
104
120
New content online: Gut microbiota in overweight and obesity: crosstalk with adipose tissue
0
46
124
New content online: Neutrophils: from IBD to the gut microbiota
0
30
116
This Review explores the role of diet, microbes & their metabolites in
#coloncancer
#CRC
#WorldCancerDay
0
103
115
New content online: Cell death in pancreatic cancer: from pathogenesis to therapy
0
45
114
NEW THIS WEEK!
REVIEW | Gut immune cell trafficking: inter-organ communication and immune-mediated
#inflammation
0
47
113
NEW REVIEW! | The role of short-chain fatty acids in
#microbiota
–gut–brain communication
#gutbrainaxis
#microbiome
1
61
113
New content online: Pathophysiology of gastro-oesophageal reflux disease: implications for diagnosis and management
3
48
113
No.7 in our top10 articles that grabbed your attention (according to Altmetrics) - this REVIEW on gut
#microbiota
metabolites as key actors in inflammatory bowel disease
#IBD
1
36
113
Best of 2021 - ALTMETRICS
no.5 is this REVIEW on Dietary carbohydrates and fats in nonalcoholic fatty liver disease
By Yki-Jarvinen, Luukkonen, Hodson &
@TheMooreLab
Read-only link
#MAFLD
#NAFLD
#fattyliver
5
27
110
New content online: Dietary management of adults with IBD — the emerging role of dietary therapy
0
50
109
What is a
#postbiotic
?
NEW CONSENSUS STATEMENT from
@ISAPPscience
on the definition and scope of the term
#openaccess
0
38
106
#MASLD
(
#NAFLD
) & alcohol-related liver disease share pathophysiological features and are leading causes of chronic liver disease worldwide
Find out more about their intersection & management in this REVIEW
#WorldLiverDay
0
46
107
REVIEW | Modern therapeutic approaches for the treatment of malignant liver tumours
2
50
102
NEW online! Nonalcoholic
#fattyliver
disease (
#NAFLD
) has become the most common form of chronic liver disease in children and adolescents. This REVIEW discusses the latest knowledge of epidemiology, pathogenesis & management
#obesity
3
55
99
0
32
102
📢Out now! This new Consensus Statement on Advancing the global public health agenda for
#NAFLD
FREE
Led by
@JVLazarus
& an international list of experts, the article aims to put NAFLD in the NCD spotlight
@EASL_ilf
#fattyliver
#MAFLD
4
58
100
NEW!
#NewsandViews
From
#NAFLD
to
#MAFLD
: when pathophysiology succeeds. Herbert Tilg &
@MariaEffenberg1
discuss the proposed name change to MAFLD - metabolic associated fatty liver disease
4
50
102
New content online: Enteric neurons and gut homeostasis
0
17
99
1
33
96
1
43
97
New content online: The promise of the gut microbiome as part of individualized treatment strategies
2
34
95
1
48
98
REVIEW | Utilizing the gut
#microbiome
in decompensated
#cirrhosis
and acute-on-chronic liver failure
This Figure summarises strategies to target the gut
#microbiota
in cirrhosis
0
34
91
REVIEW | The role of
#diet
in the aetiopathogenesis of inflammatory bowel disease
#IBD
#CrohnsDisease
#colitis
0
51
92
New content online: The intestine as an endocrine organ and the role of gut hormones in metabolic regulation
0
38
92
1
34
90
New content online: Effects of dietary fibre on metabolic health and obesity
1
31
92
NEW COMMENT arguing that now is the time tor re-examine the definition of
#NAFLD
- the vast majority of those with NAFLD do not develop clinically significant liver disease & the most frequent individual cause of death in those with NAFLD is
#cardiovasculardisease
2
48
90
Our OCTOBER FOCUS ISSUE ON LIVER FIBROSIS is live! Liver inflammation and cellular stress in fibrosis, HSCs and liver cancer, antifibrotic therapeutic strategies, and much more!
#livertwitter
#livercancer
2
28
90
NEW! REVIEW
#Microbiome
risk profiles as biomarkers for inflammatory and
#metabolic
disorders
1
39
89
Best of 2021 - CITATIONS
No.4 is this REVIEW on Advances in
#immunotherapy
for
#hepatocellularcarcinoma
Read-only link
#livercancer
0
26
89
New content online: The role of oral bacteria in inflammatory bowel disease
0
26
85
AUGUST ISSUE | REVIEW
Attaining mucosal healing without immunosuppression is an attractive option for the treatment of
#IBD
. This Review describes the mechanisms of mucosal healing and how they might be altered in IBD
2
31
87
New content online: Location is important: differentiation between ileal and colonic Crohn’s disease
2
35
84
#TBT
REVIEW | The gut
#mycobiota
: insights into analysis, environmental interactions and role in gastrointestinal diseases
#fungi
#microbiota
#microbiome
1
33
83
New content online: IgG4-related diseases of the digestive tract
0
21
81
New content online: Spatial genomics: mapping human steatotic liver disease
0
19
84
#Obesity
,
#diabetes
&
#NAFLD
can coexist, find out more in this REVIEW on the complex links between NAFLD & type 2 diabetes mellitus
#worldobesityday
1
27
83
New Review online ICYMI | Here, the authors summarize therapies for the treatment of malignant
#liver
tumours, focusing on surgical & ablative approaches & how they align with therapies such as anticancer drugs or radiotherapy. Find it here:
#LiverCancer
1
38
82
New content online: Akkermansia muciniphila: paradigm for next-generation beneficial microorganisms
2
32
81
NEW! REVIEW on the role of bile acids and their receptors in gastrointestinal and hepatic pathophysiology
0
25
79
New content online: Viscera affectum anno: the gut beyond eating behaviours
0
29
81
ILC3s orchestrate tissue physiology and immune tolerance in the gut
Check out this new REVIEW on group 3 innate lymphoid cells in intestinal health and disease
2
25
80
New content online: Lifestyle interventions in nonalcoholic fatty liver disease
2
29
81
GUT–BRAIN AXIS IN 2020 | Diego Bohorquez discusses
#GutBrain
biology in 2020 & how 3 remarkable studies have expanded our knowledge on how the
#gut
makes sense of its environment to guide brain functions & behaviors beyond food
#YearInReview
@gutbrains
0
29
78
Great session on dietary modulation of the
#GutMicrobiota
Are they ready for use as a clinical tool though?
#DDW17
0
68
78
New content online: A Roadmap for the Human Gut Cell Atlas
0
28
79
Primary biliary cholangitis (PBC) is a chronic, inflammatory & cholestatic liver disease with a variable rate of progression towards biliary
#cirrhosis
. This REVIEW highlights new insights into pathogenesis & potential therapeutic targets
1
44
77
0
21
78
ICYMI | The therapeutic pipeline for
#NASH
is expanding as insights into pathophysiology are gained, this REVIEW summarises progress in the development of NASH therapies, current & ongoing trials, and potential challenges
#NAFLD
#fattyliver
2
29
77
This Figure shows gut–liver axis barriers and anatomical connections
Find out more in this REVIEW about the gut-liver axis
0
26
75
This Figure shows the molecular mechanisms & metabolites produced by the gut
#microbiota
that act on receptors in the intestine or white and brown
#adiposetissue
Find out more in this REVIEW
0
31
76
NEW! REVIEW
Benign liver tumours: understanding molecular physiology to adapt clinical management
By
@NaultJc
@valerie_paradis
@maximeronot
@Zucmanrossi
0
26
76
New content online: Cirrhosis-associated immune dysfunction
0
23
75
New content online: Artificial intelligence in liver cancer — new tools for research and patient management
0
22
75
0
18
75
New content online: Microbiome risk profiles as biomarkers for inflammatory and metabolic disorders
1
26
74
Check out this COLLECTION on diet,
#microbiome
& homeostasis from
@NatRevGastroHep
,
@NatRevImmunol
&
@NatureRevMicro
0
25
73
#Alcohol
consumption can profoundly disturb normal functions of
#adipose
tissue, which has important direct and indirect effects on the pathogenesis of
#alcoholicliverdisease
, read more in this REVIEW £
#LiverDisease
3
62
71
No.8 is our most-viewed Reviews of 2019 -
@JasmohanBajaj
on Alcohol, liver disease and the gut
#microbiota
1
23
74
New content online: Dietary carbohydrates and fats in nonalcoholic fatty liver disease
1
25
73
Cholangiocytes, the epithelial cells lining the intrahepatic and extrahepatic bile ducts, are highly specialized cells. This state-of-the-art REVIEW provides an overview of
#cholangiocyte
pathobiology
0
31
72
Our JANUARY ISSUE is live! Pancreatic cancer therapeutics, CRC epidemiology, early-life gut microbiome, NAFLD cirrhosis recompensation and digital histology, and much more!
2
22
74
This FIGURE shows the circadian regulation of glucose homeostasis. The suprachiasmatic nucleus (SCN) signals via neuroendocrine pathways to the peripheral clocks in pancreas, gut, fat, skeletal muscle and the liver.
Find out more in this REVIEW
0
26
74
New content online: What’s new in NAFLD pathogenesis, biomarkers and treatment?
0
39
74