Jonathan Brown
@JonathanBrownMD
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Physician-scientist, fly-fisherman, family man, ice cream and live music enthusiast.
Joined July 2017
Our new publication @JCI_insight. Tremendous collaboration with Robb Flynn @VUMCresearch and @Novartis. Integration of RNAseq, chromatin signaling and CRISPR screen reveals ZNF469 is a transcriptional regulator of #fibrosis in human #MASLD, #NAFLD
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RT @SarnoffCardio: Sarnoff Members gather at Vanderbilt. Drs Scott Baldwin, Jonathan Brown and Arun Padmanabhan!
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RT @DrJMLuther: Congratulations to @DrMonaMash on publishing her latest manuscript from our @American_Heart funded study! .@JLGamboa_Velez….
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Amazing CV Research Day celebration @VUMC_heart with @alan_daugherty giving keynote address. Congrats @AzuahTheShort in @AmandaDoranLab for best student abstract. Record turnout to promote cardiovascular science @VUMCResearch.
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Outstanding CV grand rounds @VUMC_heart today from @AartiAsnaniMD on cardiac toxicities from chemotherapy and potential new therapeutic pathways. Beautiful and careful science. #VUMC #CardioOnc #HeartFailure.
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Congrats to Ronan Bracken graduate student in @JonBrownLab. Advancing to PhD candidacy in @VandyBiochem. #donewithquals!!! 🙌🧬🧬🧬.
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On clinical service now. This @statnews article really resonates. Easy to forget priorities in all the data and EHR. Be present with patients.
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Fantastic seminar from Tony Rosenzweig @VUMCResearch @VUMC_heart at our weekly research seminar in CV medicine on impact of exercise in cardiac plasticity. Next time in person for sure!.
@CardioOncology @JaneFreedmanMD @MGHHeartHealth @JenHoCardiology @pnatarajanmd @MarkELindsay @MGHMedicine @JJheart_doc @mchonig @TomasNeilan @JonathanBrownMD @JonBrownLabVUMC @VUMChealth @VUMC_heart Honored to join you all. Sorry it couldn’t be in person!.
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Important study by Dan Clark et al @VUMC_heart on #COVID19 myocarditis in athletes. Not all LGE = myocarditis. Power of comparators in research! COVID-19 Myocardial Pathology Evaluation in AthleTEs with Cardiac Magnetic Resonance (COMPETE CMR)
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Congrats on this grant. Great team exploring how dysfunctional HDL drives vascular and kidney disease.
A big congrats to Mac Linton, Kasey Vickers and team at @VUMChealth @VUMC_heart on this PPG investigating HDL function in human disease! @KaseyVickers @JonBrownLabVUMC @AmandaDoranLab @JonathanBrownMD
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Interesting read in @WSJ about role of managers in business. But, ideas clearly relevant to organizing a research lab. Managers (change to PI) as "coaches" and not authority figures.
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Read this study from Paul Cohen @RockefellerUniv about Brown Fat in humans and risk of cardiometabolic disease. Nice to see independent work from former @BrighamFellows.
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RT @TheScientistLLC: These associations are raising the really exciting notion that perhaps the presence of brown fat protects against thes….
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RT @NatRevDrugDisc: In vivo base editing shows promise in treating the genetic accelerated-aging disorder Hutchinson–Gilford progeria syndr….
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Check out this nice synopsis of our work on adenine base editor to treat #progeria @NIHDirector @davidrliu @LukeKoblan @mrrerdos @Progeria . Thanks to @broadinstitute for putting this together.
In a new Broad video, @NIHDirector, Jonathan Brown (@VUMChealth), and @davidrliu describe the impact of their recent work on treating #progeria in an animal model -- a story that began thirty-six years ago. Watch:
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#PfizerVaccine dose #2. Feels like we are closing in on an end to #Covid_19. TGIV! Great way to end the week on a positive note. Proud to be part of @VUMChealth @VUMC_heart rollout. We can beat this!
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So proud of this work demonstrating DNA base editing treatment for #progeria in human cells & mouse model. Amazing collaborative team @davidrliu @NIHDirector @LukeKoblan & Mike Erdos at NIH and my @VUMCResearch team @lindsaymdavison & Sean Doherty.
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