Michael Honigberg, MD, MPP
@mchonig
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Cardiologist + researcher @MGHHeartHealth @broadinstitute, Asst Prof @harvardmed. Preventive cardiology, women's heart health. He/him.
Boston, MA
Joined April 2009
It’s out! Thrilled to share our expanded genome-wide association study 🧬 of preeclampsia + gestational hypertension 🤰 in @NatureMedicine 🙏 to the reviewers/editors who improved this paper from the preprint Paper here: https://t.co/RTIomZfEfa Short thread 👇 (1/8)
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Excited to launch our peripartum heart failure registry! While PPCM is well recognized, HFpEF & HFmrEF in the peripartum period are under-characterized. Our goal: define this emerging population and study long-term outcomes across the EF spectrum
Peripartum🤰 HFpEF is increasingly recognized but remains poorly understood. Excited to launch the PREG-HF Registry, led by @mapabonp, aiming to characterize peripartum HF across the EF spectrum, esp. HFpEF. Please contact us if interested in joining this collaborative effort!
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Peripartum🤰 HFpEF is increasingly recognized but remains poorly understood. Excited to launch the PREG-HF Registry, led by @mapabonp, aiming to characterize peripartum HF across the EF spectrum, esp. HFpEF. Please contact us if interested in joining this collaborative effort!
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ICYMI: Taking low-dose colchicine daily may slow the progression of clonal hematopoiesis, based on a subanalysis of the LoDoCo2 trial presented at ESC Congress 2025 & simultaneously published in #JACC.🔗 https://t.co/r0A9kjzDK6
@JACCJournals #ESCCongress
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📢 #JACCばらん Ep.30「CHIPping the Code: CHIPと心血管リスクの交差点」 🎙️ゲスト:井上 峻輔 先生 @Geno_shun (東京大学大学院 医学系研究科 先端循環器医科学講座 🇯🇵/Editorial執筆) 🔍 今回は Clonal Hematopoiesis of Indeterminate Potential(CHIP) にフォーカス。
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Building on the legacy of many, I'm incredibly excited that we have successfully translated our polygenic risk scores into a validated clinical assay @MassGenBrigham @broadinstitute, orderable by any clinician in the US today. 🧬To order: https://t.co/lmPHq57sKQ 🧬Announcement:
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Low-Dose Colchicine May Slow Growth of Clonal Hematopoiesis - American College of Cardiology @NiekMohamma
acc.org
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SOO proud of rockstar 🔥💥@chrispan05 for receiving the YIA award in prevention cardiology @escardio on Psoriasis metabolomics! 🙏Grateful to all our collaborators on this project! #cardioderm @RonBlankstein @JosephMerolaMD @UTSWDerm @garshick @lfbpharmd @mchonig @artschuermans
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Wonderful exchange of science and terrific lectures by @mchonig @MassGenBrigham and @Borjaibanez1 @CNIC_CARDIO at the 8th MGB transatlantic dialogues @BrighamWomens @RonBlankstein
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So proud of these 3 for their simultaneous pubs with #ESCCongress2025 @escardio
@daniel_ezt @JACCJournals ( https://t.co/iTZGizylr2)
@NiekMohamma @JACCJournals ( https://t.co/9dTKXPWM01)
@artschuermans @JAMACardio ( https://t.co/Zd9gMIHcdX)
Major congrats to @mchonig with THREE simultaneous senior-author publications during #ESCCongress25 each with a different first-author from his group! 👏 1️⃣ https://t.co/QNE0mRPIEJ
@JACCJournals 2️⃣ https://t.co/lL4U3LogL6
@JACCJournals 3️⃣ https://t.co/oNKAAftAwl
@JAMACardio
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Major congrats to @mchonig with THREE simultaneous senior-author publications during #ESCCongress25 each with a different first-author from his group! 👏 1️⃣ https://t.co/QNE0mRPIEJ
@JACCJournals 2️⃣ https://t.co/lL4U3LogL6
@JACCJournals 3️⃣ https://t.co/oNKAAftAwl
@JAMACardio
jamanetwork.com
This study tests whether clonal hematopoiesis of indeterminate potential is associated with the development of myocarditis and pericarditis.
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Does clonal hematopoiesis of indeterminate potential (CHIP) predict heart inflammation? Thrilled to share our work identifying CHIP as a risk factor for myo-/pericarditis, with the amazing @mchonig Simultaneous pub with #ESC2025 in @JAMACardio
https://t.co/GFroe0r7wE (1/x)
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New report that CHIP (clonal hematopoiesis of indeterminate potential, blood stem cell clones that increase with age) is an independent risk factor for myocarditis and pericarditis, promoting inflammation #ESC2025 @JAMA_current
https://t.co/spxhWqXqNH
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New report that CHIP (clonal hematopoiesis of indeterminate potential, blood stem cell clones that increase with age) is an independent risk factor for myocarditis and pericarditis, promoting inflammation #ESC2025 @JAMA_current
https://t.co/spxhWqXqNH
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Among middle-aged adults, clonal hematopoiesis of indeterminate potential (CHIP) was linked to an increased risk of developing myocarditis and pericarditis. 🧵 #ESCCongress #WCCardio
https://t.co/5OcuKJVKPr
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Longitudinal analysis of the LoDoCo2 clinical trial suggests that colchicine blunts TET2 CHIP expansion possibly mediated by reductions in IL-6! These results add to a growing body of evidence that colchicine and IL-6R blockers may be beneficial for CHIP-associated CVD...
In this exploratory analysis, Tx w/ low-dose colchicine was assoc w/ an attenuated annual clonal growth in TET2 CH. Findings suggest potential for colchicine to curb proliferative advantage of key CH driver mutations https://t.co/QipRX2Dn6U
#ESCCongress #WCCardio #JACC @mchonig
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#LBCT #ESCCongress #WCCongress LoDoCo2: Effect of #Colchicine on Clonal Hematopoiesis and Inflammatory Biomarkers 🔥can colchicine slow growth of clonal hematopoiesis? 🔥looking at the LoDoCo2 study: treatment with low-dose colchicine was associated with attenuated clonal
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A superstar in the making @daniel_ezt ✨mentored by the amazing @mchonig! A very important finding showing that specific subtypes of CHIP variants were actually associated with cardiovascular outcomes in older women 👵 Full paper access: https://t.co/NuR9wO8nKy
#ESC2025
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🆕 I had the pleasure of interviewing Dr. Michael Honigberg (@mchonig ), corresponding author of two simultaneous @JACCJournals publications presented at #ESC2025, diving into the world of clonal hematopoiesis of indeterminate potential (CHIP). 🎥 https://t.co/z30qCd3PSh Even
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@daniel_ezt (6/X) Super proud of Nieky for his outstanding LBCT presentation at #ESC2025 🙏🙏 to coauthors incl @M_Mesbah_Uddin @NakaoTetsushi @pnatarajanmd and the entire LoDoCO2 team who were amazing collaborators OA paper here: https://t.co/9dTKXPWM01
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