Kira Gritsman
@Gritsman_lab
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Physician-scientist investigating signaling and self-renewal in leukemia and hematopoietic stem cells. Posts are my own.
Bronx, NY
Joined September 2011
Important PSA! The ASH Scientific Workshop website is experiencing a technical problem; YES, the Myeloid Workshop is on and should be on the website. Excellent speaker lineup ahead, stay tuned! Friday, Dec 5, 3-7 ET! π«΅ππππ«΅
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Huge congrats to @rosslevinemd and @MSKCancerCenter!
Congratulations to @MSKCancerCenter and @rosslevinemd. A phenomenal physician scientist to lead MSK!
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Agree- this is practice changing! Congratulations Kathrin Bernt and team!
Such important work for the field! I encourage all to read this new paper in @ISEHSociety's journal Experimental Hematology. Congratulations Kathrin Bernt and colleagues.
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Surprising finding that standard chemo treatment induces resistance to menin inhibitors in AML. Published in @ISEHSociety journal Exp. Hem:
exphem.org
Inhibitors of the menin-KMT2A interaction are promising agents for the treatment of KMT2A-rearranged leukemias. We evaluated menin inhibition in patient-derived xenografts of KMT2A-rearranged...
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Congratulations @SteidlUli on this very well deserved honor!
Huge congratulations to Uli @SteidlUli of @Einstein_SCI on receiving the McCulloch & Till Award 2025 @ISEHSociety in Kumamoto!! @EinsteinMed @EinsteinCellBio #ISEH2025
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Congratulations to @Amitvermamds! Such great news for Einstein!
Amit Verma, M.D., has been appointed chair of the department of #oncology @MontefioreNYC Einstein. He is a leader in the study/treatment of myeloid malignancies, incl. myelodysplastic syndrome (#MDS) and acute myeloid lymphoma (#AML). See
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The NYC leukemia working group is back for a new season! @KharasLab @rosslevinemd @Gritsman_lab @iannisaifantis1 @KentsisResearch @Elvin_Wag @FrancoIzzo85 @SKousteni @Doulatov_lab
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So excited to congratulate our MSTP student Daniel Borger, who was mentored by Paul Frenette and myself, on a successful thesis defense! β¦@EinsteinMSTPβ© β¦@EinsteinPhDβ© β¦@EinsteinCellBioβ© β¦@Einstein_SCIβ©
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Kudos to β¦@aditishasMDβ© for organizing our Einstein-Montefiore team at the Move for MDS event this morning in Battery Park and for her inspiring speech! The rain didnβt stop us!
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My institute @EinsteinMed kindly featured our recent paper presenting a new model for regulating hematopoietic stem cell numbers.πMany thanks for showcasing our work so clearly! @SteidlUli @Gritsman_lab @EinsteinCellBio @Einstein_SCI
https://t.co/udEwFxPAeY
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So proud to be part of this study as the first and co-corresponding author!π @EinsteinCellBio, @Einstein_SCI, @EinsteinMed
Nature research paper: Haematopoietic stem cell number is not solely defined by niche availability https://t.co/MCeMEImwaT
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Please check out this thread on our latest paper in @Nature on HSC pool size regulation. https://t.co/hJLrLYXXEG Phenomenal collaboration with the one and only @Gritsman_lab, and driven by the outstanding @ShoTakeishi! @EinsteinCellBio @Einstein_SCI @EinsteinMed
Excited to share our latest work @Nature! We show that the total number of hematopoietic stem cells (HSCs) in the body is restricted, challenging the classical model that HSC numbers are determined locally by the niche and introducing a new paradigm. (1/9) https://t.co/kvFqNQ8Nxb
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Very happy to contribute together with @SteidlUli to this exciting project that began in Paul Frenetteβs lab- a tour de force by the amazing @ShoTakeishi! Please check out this thread π
Excited to share our latest work @Nature! We show that the total number of hematopoietic stem cells (HSCs) in the body is restricted, challenging the classical model that HSC numbers are determined locally by the niche and introducing a new paradigm. (1/9) https://t.co/kvFqNQ8Nxb
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Thrilled that our paper is finally in press @ScienceMagazine!! *Platelets sequester cell free DNA, including free fetal and tumour-derived DNA* Tweetorial from @l_cmurphy below. Check out the news feature https://t.co/r1bXqfpPSU and terrific editorial from Dennis Lo
science.org
The cells could be a new source of tumor DNA for liquid biopsies
π¨ New paper alert! π¨ Iβm thrilled and proud to share that our latest work has just been published in @ScienceMagazine! π π§½ π Read our paper here: https://t.co/CvYSNq2nHj π¬ Watch a summary: https://t.co/qvuZR3reTj π§΅ Or keep reading for the key points! π 1/19
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We are excited to announce that The Myeloid Workshop is back on under ASH this year and will be held on Friday, Dec 5, from 3-7PM. ...π
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In our study just published in @BloodCancerJnl Outdoor Air Pollution(OAP) , particularly PM2.5 was associated with a trend towards worse survival in #multiplemyeloma patients treated in a historically redlined area - Bronx, NY. @Einstein_SCI @MontefioreNYC @EinsteinMed
Fine particulate matter exposure is linked to worse myeloma outcomes in a diverse urban cohort | Blood Cancer Journal β¦@aditishasMDβ©
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We are very excited to officially launch our single cell proteomics service!! Please, check out our website if you want to work with us! https://t.co/3beLRHphKU
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Check out our new preprint on an epigenetic resistance mechanism to PI3 kinase inhibition in AML and a new combination therapy with an EZH1/2 inhibitor that depletes leukemic stem cells! Great effort by @TheHematoPoet and the whole team
So excited to share a pre-print of my thesis work! Check it out to see how we can leverage an epigenetic resistance mechanism to PI3K inhibitors to target leukemic stem cells!! (Spoiler alert: PRC2 is involved!) Really proud of this work conducted with @Gritsman_lab
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Our trainees had a truly enriching experience at #KUHRTN2025 at @EmoryMedicine, Atlanta! They gained insights into career development, received valuable advice, and enjoyed connecting with field leaders and peers (@KUHR_Trainees) from across the country. https://t.co/C7OYWL4l4m
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Congratulations to @SteidlUli on this very well deserved honor!
Congratulations to Ulrich G. Steidl, M.D., Ph.D., who is our 14th Annual Marshall S. Horowitz Faculty Lecturer. @EinsteinMed @MontefiorePeds @RFK_Center @i_jsmiles @EinsteinPHPM
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