Giraldez Lab
@GiraldezLab
Followers
1K
Following
121
Media
28
Statuses
162
Joined May 2009
Highlighting the insightful opinion letter by @Vale_Tornini et al @thelancet on the critical importance of #Diversity, Equity, and Inclusion in science and education. Amidst challenges, we need steadfast commitment to #DEI, urging us to uphold and advance equitable practices.
0
0
7
Postdoc position in a great starting lab with an awesome pi @Vale_Tornini !!!
0
3
14
Excited to share our new study in @biorxivpreprint developing a GEARs toolbox: Genetically Encoded Affinity Reagents to visualize and manipulate gene expression. Congrats @cboswell @Caro_Hoppe 🎉 #devbio #genetictools #zebrafish
https://t.co/PEiXWiDjc2
1
55
244
Excited to share our latest paper with a novel method NaP-TRAP to quantify translation in massively parallel reporters. Congratulations @EthanStrayer, @JeanDenisB35 and all authors. Great collaboration between @GiraldezLab+Beaudoin lab
biorxiv.org
The cis -regulatory elements encoded in a mRNA determine its stability and translational output. While there has been a considerable effort to understand the factors driving mRNA stability, the...
2
23
102
🌟Fantastic time at the @GiraldezLab retreat! Deep dives into regulatory codes in development and disease, plus fun with improv @DionnaGIrons and biotech @yaleventures. Grateful to everyone for the enriching discussions and fun experiences. 🙌
0
0
35
🎉 Congratulations @Vale_Tornini | Blavatnik Awards for Young Scientists. Amazing scientist and leader. Feeling fortunate to have had Valerie Tornini in the lab soon to start her lab @UCLA . @BlavatnikAwards for Young Scientists
0
0
25
Thank you @Art4Science for the creative and fun image to illustrate our work #expansion #chromatin and #microscopy by Pownall et al
¼ This week’s fanart is from a work by Pownall et al., published in Science ° #biology #expansion #chromatin #epigenetics #genetics #microscopy #science #research #researchpaper #sciart #digital #digitalart #researchers
0
1
10
Congratulations another beautiful study by @NicoliLab led by @joey_ghersi from @YaleGenetics showing how mir-128 promotes wnt and Notch signaling to regulate hematopoietic stem cell production.
Congrats @joey_ghersi and @NicoliLab! Another lesson learned from an embryo on how tissue resilience form!
0
4
14
Congratulations @MaryC_Mullins at great scientist and role model!!!
Congratulations to @MaryC_Mullins on receiving 2023 Christiane Nusslein-Volhard Award!! This is richly deserved with your groundbreaking maternal effect Zebrafish screens, insights into BMP morphogen patterning, mentoring and @InfoIzfs leadership 🐟🔬🥂
1
0
9
Very powerful piece by a dear friend highliting a deeply personal story and the health inequalities that insurer and government can impose on people
0
0
3
The final version of our #ISMB2023 Proceedings paper UNADON, a transformer-based model to predict chromosome spatial positioning relative to nuclear bodies, is now online. @muyu_wendy_yang will present her work in Lyon during #ISMB2023.
academic.oup.com
AbstractMotivation. The spatial positioning of chromosomes relative to functional nuclear bodies is intertwined with genome functions such as transcription
We introduce UNADON, a transformer-based model for predicting large-scale chromatin spatial localization in the nucleus by considering extensive sequence context. Fantastic work by @muyu_wendy_yang. To appear in #ISMB2023.
1
11
43
Nature exhibits unparalleled craftsmanship in designing intricate structures, such as the hair follicle. We are extremely excited to have our beloved work @CellStemCell. (1/n)
Organ function is preserved despite reorganization of niche architecture in the hair follicle
4
16
52
After 7 amazing years as chair @YaleGenetics , I’m thrilled to share our opinion published @CellCellPress. Dr. Hendry and I present a complementary model for scientific leadership in departments and institutes. The Scientific Director.🙏 @CE_Hendry
https://t.co/Ke8n5DWvIQ
cell.com
The current model for academic leadership places unique demands on scientists with highly active research programs. A complimentary model with a dedicated scientific director could remove this strain...
3
46
176
Congratulations @MarkPownall5 for a great paper developing ChromExM 4000 fold volumetric expansion of the cell. 🔬🧬
Our work describing Chromatin Expansion Microscopy is now out in @ScienceMagazine
https://t.co/ysL8Q1xmqA Check out how we were able to visualize transcription, chromatin, and TFs with molecular resolution in developing zebrafish embryos to understand gene regulation!
0
3
21
We’re pleased to share our first publication from the Sozen lab, now out @Nature! Through our 3D strategy, we capture spontaneous emb. + exembr. lineage bifurcation to study aspects of early human embryo patterning, starting from a single stem cell type. https://t.co/X6Vk6YrE2m
nature.com
Nature - Human pluripotent stem cells can be triggered to self-organize into structures recapitulating early human post-implantation embryonic development.
12
64
209
Thank you @ScienceMagazine and @Cell_Tokyo_Tech Hiroshi Kimura @tim_stasevich for a great prospective on our work
science.org
A new method expands chromatin to provide detailed images of transcription sites
0
0
7
Great collaborative work with @bewersdorflab and @pioneerfactors congratulations to @MarkPownall5, @MiaoLiyun and all authors
1
0
4
🔬🧬 Excited to share our latest study https://t.co/kb3GfMrK32
@ScienceMagazine developing ChromExM which uses expansion microscopy to visualize the chromatin, transcription, RNA POL II and pioneer factor Nanog during genome activation.
9
131
628
Exciting to share the work of @Vale_Tornini, amazing leader and researcher. Micropeptides regulating chromatin and behavior in zebrafish. Great collaboration with the @realRihellab our in @eLife
https://t.co/mBzMikKZW9
5
19
117