Liz Heller
@EAHellerPhD
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proud member of the hellerlab #addiction #chromatin #blm she/her
Stuy|UPenn|RU|ISMMS|UPennSOM
Joined May 2013
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Last Seen Profiles
Recruitment party in my lab! I am looking for dedicated individuals interested in studying neuroepigenetics! TWO postdoc positions available, and one research specialist. Please DM if interested and I will send more details. Thank you for RT.
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Hiring 1 Research Specialist and 1 Postdoctoral Fellow.
Competitive salaries.
Project Title, Epigenetic regulation of Cdk5 in cognition and emotion.
Let's do this.
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I am grateful to have received a lot of positive feedback from prospective predocs this recruitment cycle. Thought I'd share my standard interview, in case anyone is new and wants a template. 1/n
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@mbeisen
Strong disagree. (1) 10 years ago they would not have included Katie in the prize, even if Drew have advocated for her. This prize going to the two of them DOES represent change. (2) In the current climate of dunking on academia and basic science, it is an essential message.
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It is my understanding that the Specific Aims page is the most important part of an NIH grant application. Can we envision a mechanism where Specific Aims page is submitted first, and then a full proposal is invited (a la Letters of Intent)? Why not?
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students -
your PIs ability to remember decades of papers by author names is because your PI is old and was present* when the project was conceived and the paper published
*as in, we know the authors irl so not that hard to remember what they did
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stop telling me that my profession is going to change
that chatgpt and ai will make me obsolete
you said that when we got the internet
and again when we got the genome
but I'm still here
VALIDATING FUCKING ANTIBODIES
by western blot
proteins don't gaf about your internets
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New paper out from incredible team of current and past Heller Lab rockstars
@SongPhd
@Sonia_Lombroso
@delaneykfischer
Chromatin-mediated alternative splicing regulates cocaine-reward behavior
🧵
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@IjeomaOluo
on
@BrianLehrer
with more words I need:
"Martin Luther King marched peacefully and he got shot in the face for it."
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Proud of this first first author paper from my first graduate student, Marco D Carpenter!
New paper out from the
@EAHellerPhD
lab in
@NatureComms
on targeting gene expression as a potential therapeutic target in cocaine addiction using mouse models
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NIH revoked funding from 14 scientists over sexual harassment last year
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Academic research is imperfect, inequitable, and underfunded.
Yet we keep at it, because it is a necessary and essential good.
Before you tweet to discourage young scientists, consider the world without public school teachers, public defenders, social workers, and librarians.
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The more time you spend planning experiments, the less time you spend repeating them. Or as my Dad said - it doesn't matter how many experiments you do, as long as you do the RIGHT experiment.
Don't devalue the effort you spend on tasks that support your research project. Updating notebook, planning an experiment,
#writing
, washing glassware or making media *is* being productive. 👉 It.All.Counts.👈
#phdchat
#PhdLife
#Postdoc
#AcademicTwitter
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Super proud of
@delaneykfischer
@mdcarpenter1331
@szhang32
and all the team for these new data:
Cell-Type Specific Profiling of Histone Post-Translational Modifications in the Adult Mouse Striatum
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I think I distilled something re: NIH grant writing.
EVERY section should include these four components in this order:
rationale->hypothesis->approach->outcome Depending on the section, one of these four components will longer and more detailed than the other three.
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"When you are accustomed to privilege, equity/equality feels like oppression." Thank you for
#speakingtruthtopower
@ImogenRCoePhD
#ACNP2019
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Related:
Them: What do you do?
Me: Faculty at Penn Med.
Them: What do you teach?
Me: I don't. I run a research program.
Them: What kind of research.
Me: Neuroscience.
Them: So great that you teach nursing.
When I tell a tech bro that I am a professor of statistics, they often immediately inform me that I am a teacher professor, not a researcher professor. I say no, I am a professor professor, I do research and teach, but mostly research. Then they tell me- oh but I’m an UNDERGRAD
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@mbeisen
CHANGE indeed. The record indicates that a female, non-faculty scientist would not be awarded a nobel.
(also ngl I'm pretty psyched you replied!)
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Super proud of Mike Murphy
@PennNGG
! This review examines Mike's hypothesis that epigenetic changes accumulate over stress/drug exposure and influence responses to subsequent exposures. Enjoy and send feedback!
'Convergent actions of stress and stimulants via epigenetic regulation of neural circuitry'
@TrendsNeuro
Review by Michael Murphy & Elizabeth Heller
@eahellerphd
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Recruitment! We are seeking a postdoctoral fellow to work on rare, genetic Epilepsies and Neuro-Developmental Disorders (ENDD therapeutics team). This project will focus on the use of epigenetic editing tools for the correction of such gene deficiencies.
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The Heller Lab is recruiting a postdoc with training in molecular biology and genetics. Please email me a CV and references if interested.
@PennEpiInst
@pennbgs
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new knowledge drop 🙌from hellerlab rockstars
Julia Winter
@DrJuliaW
@PennBPP
Kiara Rodriguez
@kiararodz_
@CAMBUpenn
Mia Dittrich
@ByramHillsCSD
alumna
Early life adversity: Epigenetic regulation underlying drug addiction ...
#addiction
@ResearchatPenn
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I'm so excited about this I'm retweeting it twice. DM me if you're looking to set this up and want to come work in my lab.
Very happy to share our latest work! Frustrated with expensive and inflexible rodent behavior testing systems, we compared
@DeepLabCut
head-to-head with 2 leading commercial systems. But first, please turn up the volume to 11 for this trailer 🙂
#Rammstein
#MachineLearning
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hot new data: significant sex differences in response
(by 2-way ANOVA of sex and behavior) to my jokes
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it's recruitment time
remember that successful scientists rarely come from the ivy+
the most rigorous, most impactful, the most 'famous' scientists, trained hard and were mentored well, at myriad schools
eg the 2024 mins 'rising star awardee' attended mt holyoke and uconn
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work for us and move to a city with multiple championship teams
even if you loathe pro sports it makes for a very happy urban atmosphere
Hiring 1 Research Specialist and 1 Postdoctoral Fellow.
Competitive salaries.
Project Title, Epigenetic regulation of Cdk5 in cognition and emotion.
Let's do this.
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Time for me to stop using Twitter. I am finding it too toxic in this long moment of fear and losses. Please forgive me for not retweeting your important thoughts for the next little while. I will dearly miss your humor. Stay safe and
#StayTheFHome
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Are we at the point in the pandemic when we put emojis in work emails?
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I took enough time off this summer (I think) because I am legit excited for the semester to start instead of terrified. I hope that there are others like me. Especially in Heller lab 😬😊
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@voM0cytosis
So I think one piece that might be important to say is that once you have a baby all of your priorities will change. Maybe not forever, maybe not in the same way, but trying to imagine how you'll do your current life after you're a parent is futile. You won't be the same person.
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We are SO excited for this.
@delaneykfischer
ready to drop knowledge on cocaine regulation of chromatin bivalency and so much more...
NGG is proud to present our next thesis defense - Delaney Fischer (
@delaneykfischer
) of the
@EAHellerPhD
lab! Please DM us for virtual access. Good luck, Delaney!
#WeAreNGG
#AlmostPhDone
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Marco Carpenter has been awarded a Postdoctoral Research Fellowship for Academic Diversity at the Children’s Hospital of Philadelphia. Congratulations, Marco!
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@drjess_s
Rev 1: kids just finished college
Rev 2: kids are in preschool and home with multiple viruses
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FUS reads histone H3K36me3 to regulate alternative polyadenylation
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So excited to announce the dissertation of
MARCO CARPENTER! Monday, March 22nd @ 2:00 p.m.
Title: TARGETING ENDOGENOUS HOMEOSTATIC MECHANISMS FOR THE TREATMENT OF COCAINE USE DISORDER: CONTRIBUTION OF NR4A1 AND TARGET GENE EXPRESSION
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Philadelphia SEPTA bus drivers are exceptional. They move my two sons and I all around town. Navigation skills like NASA. Today my driver worked with me to switch onto the bus two in front of ours at a red light. That's dedication.
@SEPTAPHILLY
#iseptaphilly
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My new reply when ppl ask me why I'm masked is to just start coughing uncontrollably.
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Very proud of Paola Eusebio-Severino, for her work this summer on stress and sex differences. Paola is a
#PennSUIP
trainee from Inter American University Of Puerto Rico - Bayamon. Here she presents her research at LANS2022.
@IDEAL_Research
@LeadershipAllia
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@Theholisticpsyc
We frame MDD as susceptibility to environmental conditions that promote depression. Under harsh conditions, most individuals are resilient and do not develop depression. As neurobiologists, we are interested in identifying molecular pathways that promote resilience.
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UPenn's department of Systems Pharmacology and Translational Therapeutics is looking for new faculty!
-understanding the fundamental aspects of neuro-immune interactions in health and disease
-cutting-edge techniques and approaches
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Thank you
@PennMedicine
ULAR/OAW for the 2021 Conscientious Investigator Award! Congratulations to Heller Lab scientist, Kyle Czarnecki
@kczar432
, whose work to improve mouse isolation housing resulted in this recognition!
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@walkerdm79
knowledge drop:
Long-Term Impacts of Post-weaning Social Isolation on Nucleus Accumbens Function
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Congratulations to
@delaneykfischer
for receiving a 2020 Trainee Professional Development Award from the Society for Neuroscience
@SfNtweets
! Great work, Delaney!
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@dennisbhooper
@HeheWaitWhut
You don't make friends with salad 🎶 You don't make friends with salad 🎶
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hey thats me
come through!
Register today for the 2024 Epigenetics Institute Symposium: Rising Stars in the Penn Epigenetics Universe! Join us 3/18/24 to hear from Bradley Bernstein, MD, PhD and Karolin Luger, PhD, as well as eight Institute Core Members! Registration required:
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second round of revision when both first and second authors have left the lab and R3 wants a whole figure of new data
#sendhelp
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Congratulations Kiara Rodriguez
@kiararodz_
on passing your prelim exam and becoming an official
@CAMBUpenn
thesis student. It is a privilege and pleasure to mentor you!
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@xtinatucker
yes please. currently very grateful for age/size appropriate Patricia Arquette in Severance and GOD BLESS most unsexy Jamie Lee Curtis in EEAAO, and always and forever Jennifer Saunders, most recently in Death on the Nile.
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unpopular opinion:
citations should be based on primacy not recency [1]
fr students think that 1999 is too old
how many times should we 'discover' that CREB is a master regulator? or that PFC projects to amygdala? everytime there is new method? eff that noise
[1]
@TronsonLab
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A proud day for me in lab:
A trainee expresses their disappointment with grace and measured optimism.
Science is full of failure. Resilience is the way.
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I'm cleaning this kitchen rug with a toothpick. How's your grant writing going?
#standardduedates
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If you are an unfunded fellowship
applicant, I send you big hugs and this helpful reminder:
[# outstanding fellowship applications >>>> $ for fellowships => arbitrary criteria determine finalists]
There's little public $ for science. But if you can, do science anyway.
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broke: advising junior female faculty to say no to service
woke: telling male faculty to say yes
E👏Q👏U👏I👏T👏Y
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A dream job would be where I worked with all my friends that I grew up with in school. Plus we got sent on cool trips for work all the time.
Oh. I have that job.
#academiaftw
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sit on study section so you can be constantly irritated by grant writing advice from ppl who do not sit on study section
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My opening speech on
@SEPTAPHILLY
: hello my name is cough Liz cough and I'm not cough sick I'm recovered from cough covid and cough flu and I'll be cough cough coughing for the rest of my life.
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I had an incredible time
@UIowaNeuro
last week and learned a ton from the faculty and trainees!
It’s hard to put into words how grateful I am for your mentorship for the last … 25 years 😵
@TedAbelneuro
🙏
Great to have Elizabeth Heller from
@PennMINS
@PennMedicine
visit us today
@UIowaNeuro
to talk about her creative work using epigenetic editing to study psychiatric disease! Honored to have worked with Liz in her early days in science!
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My 5yo just called me out for wearing the same sweatshirt every day... How long till the lab notices?
#WorkFromHome
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@voM0cytosis
I planned and I worked super hard to keep it all together. It was difficult. Yet the reasons that it was challenging were not at all what I predicted. How could I? Becoming a parent is life-altering. Gotta just embrace the insanity. It is fully charged with love.
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Big news! I'm finally able to take advantage of my employee benefit and enroll in courses!
Now I can realize my dream of
forgetting I enrolled until the final exam.
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So excited for this visit!
Save the date!
@VCARScience
hosts
@EAHellerPhD
: “Epigenetic Editing for the Study of Addiction and Depression”
Wednesday, November 30, 2022 9 am, 512 Light Hall
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the irony of a flash mob celebration for the covid vaccine nobel
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I get lots of LoR requests so I finally made some instructions and here they are in case you want to use them too
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Congratulations to undergraduate student Chloe Han for winning a CURF Fellowship for her research project: Regulation of Nr4a1 in cocaine reward! Chloe was awarded "The Endowed Dean’s Research Award" by the College Alumni Society.
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Congrats
@qiwen_hu
and
@GreeneScientist
!
Congratulations
@qiwen_hu
and
@EAHellerPhD
on this study examining histone marks and splicing during development! Though it was a preprint before, it is now published! It was wonderful to be a part of the team.
#genomics
#development
#epigenetics
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Anyone bragging how they 'don't have time to watch shows' is just admitting they don't fold their own laundry.
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a peaceful reprieve
helps me keep things in perspective
thank you Philly
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Thank you
@SyngapRF
! We are grateful and excited to dedicate our expertise to this important research area. I look forward to joining the efforts of
@GavinRumbaugh
@BateupLab
@rhuganir
and many others.
This $130k
#SRFHeller
grant to
@EAHellerPhD
puts our grants at $1M+, sourced from
#SYNGAP
families & their networks. We are 2 yrs old. Thank you to all the families who contributed, especially
@UFDisciple
for their epic effort. Enjoy todays press release!
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Recruitment! The Prosser Lab and collaborators are developing novel therapies for rare, genetic Epilepsies and Neuro-Developmental Disorders (ENDD Therapeutics team). We are hiring postdocs or research staff with molecular biology expertise. Please RT!
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I think there's a trauma associated with looking at my own face this many hours a day.
#zoomlife
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Tracy Bale
@TheBaleLab
opens
#MNS2022
with fascinating research on EV biomarkers for female adolescent trauma; collab with
@TJovanovic_PhD
featuring work by
@DocKatiePhd
et al
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shoutout to all caregivers fastening masks over tiny ears under tiny hats one million times per hour
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This was a phenomenal visit for me. I learned so much from the exceptional trainee talks. I am extremely grateful to have spent the day with all of you!
We had an exciting day at the ICAN symposium featuring Keynote Speaker, Dr. Heller from UPenn. We would like to thank all those who attended as well as our graduate students, Post doc and ICAN Committee speakers!
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Updated: Peer-reviewed and still open access!
@SciReports
Check this out if you've ever wondered whether multiple hPTMs are truly at [yfg]. We find out that cocaine regulates hPTMs at Nr4a1 differently in male and female mice
#sabv
#addiction
#epigenetics
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@tlambert03
@touchyourbrain
@gallantlab
@DrAnneCarpenter
@aexbrown
@manlius84
@nature
New to Twitter and grateful to see a citation in a tweet! Sawlid.
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undergrads in the lab mtg prepping for poster symposium on monday... after the science feedback I gave the instructions for dealing with toxicity in poster sessions... lab's response "that's the most ny we've ever seen you" 😅 #
#fugghetaboutit
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