Enrique de-Madaria
@DeMadaria
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Passionate about clinical research. Gastroenterologist, pancreatologist. Collaborative research through @ERICAconsortium . Alicante, Spain
Alicante, Spain
Joined February 2012
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Last Seen Profiles
Pinned Tweet
Our dream comes true: the
#WATERFALLtrial
has been published in
@NEJM
Aggressive fluid resuscitation in acute pancreatitis is not safe & does not improve outcomes
#GItwitter
#SomosAEG
@aegastro
What's behind this publication?
It all started 21 years ago
148
731
2K
This is my most special and exciting retweet ever!
In a randomized trial involving patients with acute pancreatitis, early aggressive fluid resuscitation resulted in increased fluid overload without improvement in clinical outcomes.
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879
Now that we have the results of the
#WATERFALLtrial
@NEJM
, how to manage fluid resuscitation in acute pancreatitis?
Don't miss this
#TheAmylaseSchool
infographics, u can print it (A4)👉 ER or GI/Surgery Departments
#UEGambassador
#SomosAEG
15
300
732
Exocrine pancreatic cancer
#TNM
staging AJCC UICC 8th edition
👉Don't miss this
#TheAmylaseSchool
infographics
#UEGambassador
#HiloAEG
@aegastro
@my_ueg
@AESPANC
@EurPancClub
@YouppiePancreas
@DHgua
#DigitalModeling
Feel free to use it (no copyright) but share it! 🙏RT
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What are the etiologies of Acute Pancreatitis? This is a frequent problem we face in clinical practice, this infographics will help you for the sometimes difficult quest for a cause!
#TheAmylaseSchool
@aegastro
#UEGambassador
Feel free to use this infographics, no copyright
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Protocolo de manejo de fluidoterapia en pancreatitis aguda con lo aprendido del ensayo clínico
#WATERFALLtrial
en español, puedes imprimirlo y ponerlo en urgencias o los servicios de digestivo, interna y cirugía, traducción hecha por el mismísimo
@LlorensPere
!
@isabial_iis
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437
How to do a pro search in Pubmed?
This special
#TheAmylaseSchool
infographics (or mini-course) is a guide to navigate the deep waters of Pubmed (and not get drown). I provide a pdf at the end of the Twitter Thread
1/5
Author Journal Date Title Abstract Language Affiliation
👇
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431
Antibiotics in acute cholecystitis and cholangitis
👉Microorganisms 🐛🪲🦠
👉Initial empiric antibiotics 💊💉
👉 Based on Tokyo Guidelines 2018 🇯🇵
See thread for the article and definition of severity
🙏 RT & follow!
#TheAmylaseSchool
#UEGambassador
@my_ueg
#HiloAEG
@aegastro
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What is the clinical importance of pancreas divisum?
@my_ueg
#UEGambassador
@aegastro
@EurPancClub
@hpb_so
@me4_so
#EndoSoMe
@SEEDendoscopia
#PancreasHGUA
@DHgua
#Pancreatitis
👇🏻👇🏻👇🏻
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Sometimes pancreatitis involves the duodenum, let´s talk about paraduodenal/groove pancreatitis
Don't miss this
#GItwitter
thread based on my talk for
@harvardmed
@HMSPostgradCE
#HarvardMINT2022
course
Thanks,
@CharuParanjape
@krishnanendo
for one of my best experiences ever!
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Visual guide to Colorectal cancer
#TNM
staging AJCC UICC 8th edition, a
#TheAmylaseSchool
infographics
#UEGambassador
#HiloAEG
@my_ueg
@aegastro
@Rodrigus01
@castells_toni
@frankbalaguer
@MoreiraR_Leti
@JoaquinCubiella
@aecirujanos
@_SEOM
@Baricorcho
@almagoch
@Vilavaite
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1/5
@pancreatitis_nl
trials addressing the management of infected pancreatic necrosis in acute pancreatitis
#TheAmylaseSchool
@my_ueg
@EurPancClub
@MarcBesselink
#ClinicalResearch
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Cross-sectional imaging often reveals unexpected pancreatic cystic lesions, it is a frequent clinical problem, Should we observe or remove it? What's the diagnosis? Is our patient in danger of malignancy?
Don’t miss this
@aegastro
@my_ueg
#EducAEG
#UEGambassador
twitter thread
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Severity criteria for acute pancreatitis, acute cholecystitis and acute cholangitis
#TheAmylaseSchool
#UEGambassador
@my_ueg
#HiloAEG
@aegastro
@gastromx
@sage_gastro
@almagoch
@OPGEgastro
@aecirujanos
@SEEDendoscopia
@lelecapurso
@MarcBesselink
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What is a Groove Pancreatitis (GP)?
#GroovePancreatitis
#ParaduodenalPancreatitis
#CysticDystrophyDuodenalWall
What are the symptoms, consequences, management?
Do not miss this
@aegastro
#HiloAEG
#UEGambassador
@my_ueg
Twitter thread
#TheAmylaseSchool
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No puedo evitar emocionarme al ver este papel azul plastificado con un cordel, dos décadas de madrugar mucho para esto...
@HMSPostgradCE
@harvardmed
@isabial_iis
@GVAsalualicante
@GVAsanitat
@UniversidadMH
22
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100 publications as author in Pubmed 😊, a big effort behind the scenes, waking up daily at 5:15 am almost every day in the last 20 years. Many mentors and collaborators made it possible
@isabial_iis
@GVAsalualicante
@DHgua
@magarlonso
@GVAsanitat
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Maastricht VI/Florence consensus report, Management of Helicobacter pylori infection, Malfertheiner
@emadelomar
@jp_gisbert
et al,
@Gut_BMJ
Have a look at this
#TheAmylaseSchool
infographics PART I:
1/4 INDICATIONS/ASSOCIATIONS
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R u a
#ClinicalResearchLover
? Subscribe to my weekly newsletter
#DeMadariaVsPlacebo
, today I published the 1st one in 🇬🇧&🇪🇸:
👉The p-value of tea and milk: the algae specialist and the tea-value
Learn about the famous Lady Tasting Tea experiment
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Can procalcitonin safely guide antibiotics in acute pancreatitis?
@LancetGastroHep
PROCAP study is the answer
Infographics based on the abstract, full paper:
Read the Editorial by
@lelecapurso
and me in
#TheAmylaseSchool
@my_ueg
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One of the most frequent daily problems: the lack of time, deadlines, too much work...
How to deal with that precious and volatile substance called TIME? How to deal with many projects at a time?
Don´t miss this
#UEGambassador
@Twitter
thread
@my_ueg
RT and follow me!
👇👇👇
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ERCP in acute pancreatitis, should we run, or ERCP can be delayed? What's the evidence from Randomized Controlled Trials (RCTs)???
Don't miss this
@aegastro
#HiloAEG
@my_ueg
#UEGambassador
Twitter thread
#PancreasTwitter
#TheAmylaseSchool
Look at the final summary figure!
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Time for a very interesting question: which is the best type of fluid for resuscitation in acute pancreatitis?
IS IT LACTATED RINGER'S SOLUTION???
Don’t miss this
#UEGambassador
#HiloAEG
#GItwitter
thread
@my_ueg
@aegastro
#TheAmylaseSchool
🙏 share!
👇👇👇
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1/4
Have a look to this infographics about Helicobacter pylori (you can use these slides in any educational activity)
#HarvardMINT2022
#HiloAEG
#UEGambassador
#GITwitter
@my_ueg
@harvardmed
@krishnanendo
@CharuParanjape
@MGH_GI
@YhernandezMD
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1/6 I am very honored, proud and excited to receive the prestigious United European Gastroenterology (UEG) Research Prize!
Exciting news! 🏆🎉 We're thrilled to announce Enrique de Madaria as the winner of our
#UEGResearch
Prize 2024. His exceptional work has pushed the boundaries of knowledge in acute and chronic
#pancreatitis
. Congratulations, Enrique! 🌟
@DeMadaria
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1/2 So honoured that the
#WATERFALLtrial
has been considered the first of the top 10 gastroenterology publications in 2022 by
@Medscape
!
Proud of our collaborators from 18 centers that joined WATERFALL and believed in the project, guys thanks!
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Honored to deliver an invited State-of-the-Art lecture during
@DDWMeeting
#DDW23
Chicago 2023 on the early management of acute pancreatitis
#GItwitter
#SomosAEG
@aegastro
@EurPancClub
1st invited talk in DDW ever!
@isabial_iis
@GVAsalualicante
@SaludISCIII
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Un día muy importante para mí: hoy se inaugura la unidad bilio-pancreática de
@DHgua
.
@KarinaCrdenasJ1
y yo nos ocuparemos de la parte clínica de las enfermedades biliares y pancreáticas.
@GVAsanitat
@GVAsalualicante
@encarnallinares
@magarlonso
@anabarcelochico
@aegastro
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Our review on fluid resuscitation in acute pancreatitis has been published in Annals of Internal Medicine
@AnnalsofIM
@Lguilabert1
Fluid Resuscitation for Noncritically Ill Patients With Acute Pancreatitis
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Imaging features of autoimmune pancreatitis
#UEGambassador
#TheAmylaseSchool
#GItwitter
#PancreasTwitter
#HiloAEG
@my_ueg
@aegastro
#3Dmodeling
More details during my talk about autoimmune pancreatitis in the upcoming
@EurPancClub
meeting, see next tweet
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Recibir este mensaje de un alumno de la
@UniversidadMH
@MedicinaUmh
y pensar que es el reconocimiento más bonito que me han dado 🥲
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Awesome video crafted by
@NEJM
explaining the
#WATERFALLtrial
Management guidelines for acute pancreatitis recommend early aggressive fluid resuscitation, yet evidence supporting this approach is limited. New research findings are summarized in a short video.
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Pancreatic exocrine insufficiency: causes, consequences, diagnosis and treatment.
Don´t miss this
@my_ueg
#UEGambassador
twitter thread
#PancreasHGUA
@aegastro
@AESPANC
@EurPancClub
@Pancreatology
@hpb_so
@me4_so
#SoMe4Surgery
@GVAsanitat
@GVAsalualicante
@isabial_iis
10
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Dear friends, join us in the
#GALADRIELtrial
, the continuation of
#WATERFALLtrial
.
We will compare lactated Ringer solution vs normal saline in patients with acute pancreatitis
Does Ringer improve outcomes? International multicenter RCT. Again, we have funds from
@SaludISCIII
☺️
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So touched and proud to see the impact of our
#WATERFALLtrial
on the new american acute pancreatitis clinical practice guidelines
@AmJGastro
@AmCollegeGastro
@ERICAconsortium
A 20~year voyage!
👇🏻
Our dream comes true: the
#WATERFALLtrial
has been published in
@NEJM
Aggressive fluid resuscitation in acute pancreatitis is not safe & does not improve outcomes
#GItwitter
#SomosAEG
@aegastro
What's behind this publication?
It all started 21 years ago
148
731
2K
9
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Diagnosis of pancreatic exocrine insufficiency, not an easy task! Algorithm for the symposium Disorders of the pancreas and liver: sharing experiences in today's realities (Moscow)
#UEGambassador
#TheAmylaseSchool
#HiloAEG
@my_ueg
@UEGJournal
@aegastro
#GItwitter
#PancreasTwitter
4
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Revised version!
What are the steps for a successful clinical research career? How can you develop projects to change current clinical practice? How to become an excellent clinical investigator? Where are you now in your research career?
#UEGambassador
@my_ueg
12
66
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Causes of high serum amylase, a frequent clinical problem!!!
#TheAmylaseSchool
#UEGambassador
@aegastro
#HiloAEG
Inspired by the excellent
@SanthiVegeMD
's article for
@UpToDate
15
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1/5
This is an easy visual guide addressing the Kyoto international consensus report on anatomy, pathophysiology and clinical significance of the gastro-oesophageal junction published in
@Gut_BMJ
@emadelomar
Read this Twitter thread!
#TheAmylaseSchool
#UEGambassador
#Foregut
5
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La crisis del coronavirus ha interrumpido los rotatorios de residentes en
@DHgua
#PancreasHGUA
. Tenía preparadas charlas para los rotantes que estoy grabando:
#RotatorioVirtualPancreas
La 1ª trata de los quistes y neoplasias quísticas pancreáticas (30min)
31
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Splenic vein thrombosis in chronic pancreatitis
Patient with an acute flare of inflammation in chronic pancreatitis. CT scan showed a normal splenic vein but 8 days later pain worsened and a new CT scan showed splenic vein thrombosis
See this
#UEGambassador
twitter thread
@my_ueg
11
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During the pandemic, a group of people with an interest in gastroenterology education through Twitter created strong bonds of friendship; yesterday we met for the first time, and it was amazing!! From Canada to Australia...
Missing those who didn't attend
@DDWMeeting
#DDW2022
10
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Pancreatic exocrine insufficiency after a Whipple procedure/ cephalic duodenopancreatectomy
#TheAmylaseSchool
#DigitalModeling
#MedArt
#Medicalillustration
More info in this
@AnnalsofSurgery
Systematic Review from our group:
1
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Después de 14 años en la unidad pancreática del
@GVAsalualicante
, hoy he podido consolidar mi plaza, con mucha alegría y con muchas ganas de seguir con nuevos proyectos
@GVAsalualicante
@GVAsanitat
@anabarcelochico
@CarmenMonton
@isabial_iis
41
9
169
Quick introduction to autoimmune pancreatitis, based on my recent talk in the
@EurPancClub
meeting
#EPCKyiv2022
#GItwitter
#TheAmylaseSchool
#PancreasTwitter
#PancreasLovers
#MedTwitter
👇👇👇
11
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The in press pre-proof of the new International evidence-based Kyoto guidelines for the management of intraductal papillary mucinous neoplasm of the pancreas is available!
#Pancreatology
Good reading, only minor changes from the Fukuoka 2017 guides
2
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Que un médico tenga que invertir su tiempo libre en estudiarse cosas como la ley del gobierno valenciano para una oposición a la plaza que lleva ejerciendo más de una década tiene la misma lógica que preguntar en una oposición a juez sobre la glomerulonefritis mesangial
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So honoured to have been appointed
@AmerGastroAssn
Councillor for the Pancreatic Disorders section!
@DDWMeeting
Thanks to
@AmerGastroAssn
and section chair and vice-chair Vikesh Singh and
@raman_muthusamy
!
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During
@DDWMeeting
we had the opportunity to discuss new studies on fluid resuscitation
The study was stopped for safety reasons
@BilalMohammadMD
@BalissMichelle
@Jonathansegal85
@helpatologist
@SunilAminMD
@KM_Pawlak
@KralJan
@stevenbollipo
@Samir_Grover
@nataliejowilson
16
12
159
Annular pancreas
#TheAmylaseSchool
#UEGambassador
#HiloAEG
#PancreasTwitter
#TicTacBoborodada
@Vilavaite
@almagoch
@chuletadeosler
👇👇👇👇
9
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Massive peripancreatic fat necrosis without pancreatic gland necrosis in acute pancreatitis. Pain (the patient can’t sleep despite morphine) and a very hard abdominal mass, no suspicion of infection. Drain or wait?
42
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My great grandfather, José de Madaria, a physician specialised in electrotherapy in Orihuela, Alicante, Spain, >100 years ago
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Excited about the
#WATERFALLtrial
metrics! Aggressive vs moderate fluid resuscitation in acute pancreatitis
>40,000 page views
On the 98th percentile of
@NEJM
papers
On the 99th percentile of other medical journals
9
10
153
To receive this email is so touching for a gastroenterologist living in a small coast city in Spain 🥲
@harvardmed
#SomosAEG
#HarvardMINT2022
@GVAsalualicante
@isabial_iis
@UniversidadMH
@dmedicina_umh
@MedicinaUmh
@RADIO_UMH
Join us in the MINT course:
21
7
148
Muy emocionado de celebrar una curación, el caso más difícil al que nos hemos enfrentado
Mucha gente y muchas especialidades y profesiones sanitarias trabajaron 15 meses para conseguirlo
@japariciot2
@juanacasellas
@ramia34
@GVAsalualicante
@MaryanaBozh
7
14
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Excited to present
#WATERFALLtrial
on
@DDWMeeting
#OralPresentation
Aggressive vs Moderate fluid resuscitation on Acute Pancreatitis, an international randomized controlled trial
#GIgang
#GItwitter
@isabial_iis
#SomosAEG
@DHgua
23
31
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What are the risk factors for pancreatic cancer?
Don't miss this
#TheAmylaseSchool
#UEGambassador
#HiloAEG
infographics
@aegastro
@my_ueg
@AmerGastroAssn
@NatRevGastroHep
@YouppiePancreas
@IHPBA
#GItwitter
#PancreasTwitter
Feel free to use it (no copyright) but 🙏share it!
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Today it´s 20 years since I started my gastroenterology fellowship at
@DHgua
@GVAsalualicante
@GVAsanitat
Please, find in this
#UEGambassador
@twitter
thread what I have learned throughout these years about being a physician
@my_ueg
👇👇👇
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La persona con una enfermedad grave e incurable es la que más necesita nuestra atención y empatía, me ha emocionado reencontrar esta nota. Sentir que hayas podido reconfortar a alguien en esta situación es una de las cosas que hacen nuestra profesión maravillosa
6
11
144
Alucinando con impact factor 2021 de
@gastroHepato
, revista de
@aegastro
@AEEHLiver
@geteccu
: ha pasado de 2,102 a 5,867. Única revista de gastroenterología en español en 2º cuartil
Merece la pena publicar en
@gastroHepato
!
Felicidades a
@frankbalaguer
@pilarnos
@macarlotal
8
42
141
Let´s see the types, risk and protective factors for biliary stones
#UEGambassador
#TheAmylaseSchool
#HiloAEG
@my_ueg
@AESPANC
#GItwitter
#StoneAge
#Gallstones
5
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3
33
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The scariest esophageal foreign body ever, from esophagus to aorta (safely removed by means of endoscopy by
@NeftaliJaraMDI1
, an epic heroine)
(Look at the CT scan in the twitter thread)
#MedTwitter
#GIgang
#UEGambassador
@DHgua
@japariciot2
@Belenmm271
👇🏻👇🏻👇🏻
18
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I am 47 y/o, I have been pancreatologist since 2005, after 17 years, I feel not prepared and insecure to tell somebody he or she has pancreatic cancer. 3% 5-year survival
This must change, we, as citizens, must pressure to change this fact
#WPCD
@EurPancClub
@worldpancreatic
7
22
136
Consulta médica de mi hija pequeña
Detalle: "mascarilla obligatoria"
Atiende urgencias imaginarias de sus primas
15
5
135
So,
you can also do it! Just choose the right question, and start to walk, step by step, no rush
Good night
4
4
135
Honored to be appointed yesterday as an International Association of Pancreatology (IAP) Council member
The IAP is devoted to education, collaborative research and promoting public interest in pancreatology
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133
Today, while taking my 13-year-old daughter, Maria, to high school, she told me she had written a short composition about me for her English class. It is a teenager's perception of her father's academic work. The last paragraph about the impact in family life moved me!
16
8
132
Recién recibido mi ejemplar de Enfermedades inflamatorias del páncreas, el libro que hemos editado 3 amigos, Gustavo Kohan,
@oscarmazza
y yo, con el trabajo de muchos pancreatólogos argentinos y españoles
👇🏻👇🏻👇🏻
España:
Argentina:
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Acute abdominal pain. What is the diagnosis according to the image? You have 5 seconds. Retweet if you know the answer
Sometimes we forget that a simple abdominal X-ray can give you an accurate diagnosis of an abdominal disease
#UEGambassador
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I'll do it tomorrow: procrastination in clinical research, how to face your academic tasks without feeling anxious.
Don't miss this
#DeMadariaVsPlacebo
post!
Subscribe if you are a
#ClinicalResearchLover
and share the post if you found it useful
16
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Paraduodenal pancreatitis,
#TheAmylaseSchool
infographics
#UEGambassador
If u want to know more or u love esophageal/gastric/duodenal diseases
#Foregut
, be updated via a
@harvardmed
awesome course, register NOW for
#HarvardMINT2022
Sep 29/Oct 1
🙏 share!
4
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Me pregunto, ¿qué pasaría si en la evolución de nuestros informes de alta llamásemos al paciente por su nombre (no “mujer de 77 años”)?¿y si explicásemos lo que le ha pasado en un lenguaje comprensible para el paciente y su familia?
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Join me at the
@DDWMeeting
in Chicago, May 6, 2023! My first invited talk at DDW. I will be speaking a State of the Art Presentation on Early management of acute pancreatitis
#DDW2023
#HereforDDW
8
13
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Carreras contra el Cáncer de Páncreas Madrid (14 nov),Alicante (21 nov) y Virtual (18-21 nov) en resto de España:ayuda a financiar proyectos de investigación,
ayúdanos a difundirlo en tu provincia, habla con compañeros y amigos,apoyad la investigación🙏🏼 RT
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Ha sido un honor ser presidente de
@aegastro
en los últimos 3 años, junto a
@drapereza
como secretaria
Los mejores 3 años de mi vida profesional gracias a una junta de gente buena, apasionada y trabajadora
Esto es lo que ha hecho la junta en este tiempo
#HiloAEG
#AEG2023
10
21
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Por favor retuitead!!!
Estimado
@TwitterEspana
¿podéis desbloquearnos la cuenta
@Run4Pancreas
? Es una cuenta para promocionar una carrera para obtener fondos contra el cáncer de páncreas, lo hemos intentado todo para reactivarla y ha sido imposible
🙏🏼🙏🏼🙏🏼🙏🏼🙏🏼🙏🏼🙏🏼🙏🏼
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1/3
What is the definition of microlithiasis and biliary sludge?
Have a look at this consensus led by
@JuliaMayerle
@MZorniak
@SimonSirtl
@georg25985747
@Gut_BMJ
👇🏼👇🏼
3
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I just submitted the results of the
#WATERFALLtrial
to
#DDW2022
@DDWMeeting
Aggressive vs Moderate Fluid Resuscitation in Acute Pancreatitis: an international (4 countries) multicenter (18 hospitals) randomized clinical trial
Dreaming with this study since I was a resident!
22
25
118
Is COVID-19 associated to pancreatic damage? >amylase/lipase not enough to discriminate it as those patients have several factors associated with >enzyme levels other than pancreatitis, read our letter published on Gastroenterology
@AGA_Gastro
@drkeithsiau
17
57
113
A Whipple procedure in 10 seconds
#PancreasTwitter
#Pancreatoduodenectomy
#AdobeAfterEffects
@AdobeES
5
32
114
Los compañeros de
@PancreasVerona
han desarrollado la aplicación iCyst, con las guías europeas de manejo de los quistes pancreáticos. Está disponible en Apple Store y para Android, imprescindible para manejar este problema tan frecuente en la consulta!
#PancreasTwitter
6
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Hoy se va del
@DHgua
@GVAsalualicante
una profesional impresionante,
@KarinaCrdenasJ1
, excelente clínica, investigadora, endoscopista, docente y persona. Ha evolucionado tanto en 5 años que da vértigo
El hospital de Alcoy es muy afortunado!
Sigue brillando Karina!!
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As an expert in fluid resuscitation in acute pancreatitis, I have been invited to write an article on "Evaluation of Wastewater Pollution Control Technology" by a wonderful predatory journal
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¿Quieres prepararte una oposición médica y estás desorientado y desanimado sin saber cómo hacerlo? ¿Te agobias por no tener tiempo por hijos, privada...?¿Pensando en tirar la toalla?
Lee este hilo, esto es todo lo que aprendí en la OPE que aprobé, basada solo en test
👇👇👇
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Systemic involvement, autoimmune pancreatitis type 1- IgG4 disease
#TheAmylaseSchool
#UEGambassador
#HiloAEG
@my_ueg
@aegastro
@AESPANC
@YouppiePancreas
#GItwitter
Full talk during the upcoming
@EurPancClub
meeting Ukraine June 2022, join us!
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What are the etiologies of acute
#pancreatitis
?
TO
IMAGINE
I have created this mnemonic for my talk on the upcoming
@UEGweek
Virtual 2020 on a case of drug-induced acute pancreatitis
@my_ueg
#UEGambassador
#PancreasTwitter
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In just 3 weeks we have recruited patients from Spain, India, and Pakistan in the
#WATERLANDtrial
Ringer vs normal saline in acute pancreatitis, an international open-label RCT
So excited about this!
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What are the steps for a successful clinical research career? How can you develop projects to change current clinical practice? How to become an excellent clinical investigator? Where are you now in your research career?
Don't miss this
#UEGambassador
@my_ueg
@Twitter
thread
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1/2
Awesome experience! Visiting the Massachussets General Hospital
@MGH_GI
@MGHMedicine
with
@krishnanendo
@YhernandezMD
I saw the
#WATERFALLtrial
protocol posted on the wall by the nurses, the aggressive arm was crossed out and they wrote "no longer', moderate: "new"
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Guidelines addressing the management of pancreatic cystic lesions, choose your preferred one!
@AmerGastroAssn
2015:
Fukuoka 2017:
European 2018:
WGO 2019:
@my_ueg
#UEGambassador
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