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Jan Král Profile
Jan Král

@KralJan

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MD, PhD, MSc, MBA at @FnMotol | Interests in #IBD, #Endoscopy, #LiverDiseases, #BariatricEndo, #AI, #3DPrinting - https://t.co/ROG5kRobku, #ESGE SoMe WG

Prague, Czech Republic
Joined September 2010
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@KralJan
Jan Král
1 day
⚠️Complicated diverticulitis = IV antibiotics (ceftriaxone + metronidazole or pip-tazo) + interventions if needed (e.g. abscess drain, colectomy) 💉 Mortality: 0.5% elective vs 10.6% emergent surgery ⚠️ #Surgery #Colorectal
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@KralJan
Jan Král
1 day
Only 1–4% of diverticulosis cases → acute diverticulitis 🔥 Most (85%) are uncomplicated ✅First-line = observation, clear diet, & acetaminophen 🥣💊 Antibiotics reserved for select high-risk groups (e.g. fever, immunocomp, elderly) #MedEd
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@KralJan
Jan Král
1 day
#Diverticulitis affects 180 per 100K people in the 🇺🇸 annually 200K hospitalizations & $6.3B in costs 💸 Risk rises with age, genetics (e.g. TNFSF15), BMI ≥30, NSAIDs, & DM2 🧬 📕🔗 https://t.co/Mgwz044wni #GITwitter #MedTwitter @JAMA_current @AmerGastroAssn 📊🦠💥🏥
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@helpatologist
Nadeem Tehami
2 days
#ValladoLIVE2025 concludes By far the best therapeutic #EUS live endoscopy event I’ve attended! 🌍 World-class faculty, incredible complex cases, and the very authors of key trials & guidelines performing live. Grateful & privileged to be included. Thank you, Manolo! 🙏
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@KralJan
Jan Král
3 days
#IFSO should drop misleading sleeve labels from its Atlas 🚫. “Mini” isn’t safer, better, or proven. One SG technique, evidence-based & standardized, must guide practice—not flashy labels. 📚 @DiogoPhd @Bariatric_doc @PopovVioleta @allie_schulman @my_ueg
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@KralJan
Jan Král
3 days
⚠️No outcome benefit for ultra-tight sleeves (≤32Fr) vs 36–40Fr 📊. ⚠️Smaller bougies ↗️ leak rates & reflux. “Mini sleeve” ≠ better results, just more complications. ✅Guidelines recommend 32–40Fr with 2–6 cm antral preservation. ⚠️ #BariatricSurgery #MedTwitter
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@KralJan
Jan Král
3 days
🚨“Mini”, “Midi”, “Super” Sleeves in SG? 🚫 These terms are not backed by evidence or guidelines. Used in the IFSO Atlas, they reflect marketing—not science‼️ ✅Let’s clarify why terminology matters in bariatric surgery. 🗂️ 🔗 https://t.co/S6l9GHimgS #GITwitter #MedEd
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@KralJan
Jan Král
7 days
⚠️3D colonoscopy improves adenoma detection—especially tricky flat & proximal ones without longer inspection time 🔍👏. Is it time for 3D to become the new standard? 🧑‍⚕️💬
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@KralJan
Jan Král
7 days
✅3D colonoscopy significantly boosted ADR vs 2D (53.1% vs 38.6%; P=0.009). ✅Detection of flat (35% vs 21.5%), right-sided (26.3% vs 15.2%) & proximal adenomas also improved 📈. Inspection time? Practically the same ⏱️. #MedEd @aegastro @SEEDendoscopia @BritSocGastro
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@KralJan
Jan Král
7 days
🧐Can better visuals mean better detection? ✅RCT compared 3D vs 2D colonoscopy in >300 patients. 3D imaging enhanced anatomical detail, but did it help find more adenomas? 🤔📸 🔗 https://t.co/ALmP6Imb9J #GITwitter #Endoscopy #MedTwitter @ESGE_news @ASGEendoscopy @my_ueg
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@KralJan
Jan Král
8 days
🔥 Hands-on with #ESGEatUEGWeek in Berlin 🇩🇪 Great to see @LumirKunovsky & team bringing world-class #endoscopy training 🙌 #UEGWeek2025 @my_ueg @ESGE_news
@LumirKunovsky
Lumír Kunovský
8 days
📢 #ESGE Hands-on training at #UEGWeek 2025 🔥 ✅️ Join us❗️ 💥 Have a great #UEGWeek 2️⃣0️⃣2️⃣5️⃣ everyone! ✅️ #Berlin #Germany 🇩🇪 🔴 #ESGEatUEGWeek 🔴 🟢 @my_ueg 🟢 🔵 @ESGE_news 🔵 ➡️ https://t.co/zYzgubX2i7 ⬅️ #endoscopy #gastroenterology
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@neilRsharmaMD
Neil Sharma, M.D. FASGE, FACG, AGAF
9 days
Cleveland clinic Van endoscopy conference had a strong international showing this year. Great to see where Dr Roberto Simons-Linares has taken it! What an amazing community - honored to be faculty and part of the culture. #Gastroenterology #GITwitter
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@LumirKunovsky
Lumír Kunovský
9 days
🔥🔮 The new era begins❗️🔥 ✅️ Just be smart 💡 🔴 First use of a 3D-printed 🖨 distal attachment cap for #endoscopic submucosal #dissection 🔪🩸 ✒️ @KralJan 💥💥💥 📘 @FrontGastro_BMJ 🤗 👉 https://t.co/PdhpkwuYwS @BritSocGastro @imedverse @Innov_Medicine #GITwitter
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@KralJan
Jan Král
9 days
EASO on liver disease: ✅metabolic dysfunction–associated steatotic liver disease / steatohepatitis respond to tirzepatide 🩺 Personalize by complication burden, safety, patient values, and access
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@KralJan
Jan Král
9 days
Per EASO, choose by complication: ✅obstructive sleep apnea → tirzepatide ✅knee osteoarthritis pain → semaglutide 🦵 ✅type 2 diabetes or prediabetes → tirzepatide or semaglutide ✅established cardiovascular disease → semaglutide ❤️ ✅ heart failure → either 🫀
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@KralJan
Jan Král
9 days
#EASO framework urges complication-centric #obesity care 🔬 ⚖️ Treat organ dysfunction and quality of life, not kilograms alone 🧠 🤝 For the largest weight loss and broad metabolic benefit, consider tirzepatide or semaglutide 📈 🔗 https://t.co/99ooSyaeks #GITwitter #MedEd
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@KralJan
Jan Král
12 days
🚨 Abstracts are OPEN for #ESGEDays2026 🚨 Excited to see all the cutting-edge research that will be presented in Milan 🇮🇹✨ 👉 Don’t miss the chance to share your work with Europe’s leading #endoscopy community! #GiTwitter #MedEd #MedTwitter @LumirKunovsky @drkeithsiau
@ESGE_news
ESGE
12 days
📢 The #ESGEDays2026 abstract submission platform is officially open! 📢 Be a part of Europe's leading endoscopy meeting by submitting your best research - we look forward to showcasing it in fantastic Milan! All the details here: ➡️ 🔗 https://t.co/aTlmGBQnc1
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@KralJan
Jan Král
13 days
🌎That was #CADEC2025 at Cleveland Clinic‼️ 🎓 Top-tier lectures 🎤, world-class faculty 🧠 & next-level hands-on sessions 🖐️. Already counting days to #CADEC2026! 🗓️✨ #GITwitter #Endoscopy #MedEd #MedTwitter @ESGE_news @ASGEendoscopy @ClevelandClinic
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@KralJan
Jan Král
14 days
🙏Wonderful hands-on vibes at CADEC 2025! 🙌✨ Scopes, skills & smiles all around 💥🖐️📹 Every moment a masterclass . Thank you Roberto for the 🔝 guidance & endless inspiration! 👏💪 #GITwitter #Endoscopy #MedEd #CADEC2025 @RobertoSimonsMD @MetabolicEndo @SighPichamol
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