My first day at @sangerinstitute was rainy but very exciting nonetheless. As a @Cambridge_Uni PhD student I will be venturing into other genomics niches; away from human medicine even. My first project in the Tree of Life is extremely interesting and inspiring!

High point at #GenomicsAtScale25 with a very cool talk by @hana_aliee. She's hiring so make sure you apply!!

Gabriele Picco @GabrielePicco2 from the Sanger Institute at #GenomicsAtScale25

Wes Robertson from the MRC-LMB at #GenomicsAtScale25

Fantastic talk 🤯

(1/12) Over a year ago, we launched a new project to explore whether the tissue microenvironment could predict cellular behaviour and whether reprogramming might unlock new therapeutic avenues. 🧬 Spatial transcriptomics provides deep insights into tissue organisation. We

(1/n) The first preprint from our lab is now out in @NatureGenet! We tried to tackle a key challenge in spatial biology to quantitatively characterizing cellular niches by learning spatial gene programs using NicheCompas led by @SebastianBirk_. Paper: https://t.co/5geev3s0mV

This is not terrorism but it is terror —a hallmark of authoritarianism.

1/ 🧬 Single-cell genomics reveals biological variations beyond cell types. Unveiling these in separate latent dimensions is known as disentanglement. Led by @AmirAliMoinfar, we introduce DRVI to learn nonlinear, disentangled & interpretable latent spaces. https://t.co/Kuowzgpc97

Spapros developed by @fabian_theis and colleagues is a probe set selection and design pipeline for targeted spatial transcriptomics. https://t.co/vISHcs0b6b

What geneticists fear the most: The Cambridge Plot.

The #NobelPrizeinPhysics2024 for Hopfield & Hinton rewards plagiarism and incorrect attribution in computer science. It's mostly about Amari's "Hopfield network" and the "Boltzmann Machine." 1. The Lenz-Ising recurrent architecture with neuron-like elements was published in

This week in key Covid publications: —Young, healthy individuals with mild cases had objective cognitive deficits at 1-year that they did not perceive —Older, hospitalized adults with severe Covid had an equivalent of 20 years of decline in cognitive performance at 1-year

My friend @THJimmyLee is fundraising for Alzheimer's Research UK. Check out their @JustGiving page and please donate if you can. THANK YOU! #JustGiving

Happy that our ehrapy toolbox for the exploratory analysis of electronic health records is out today @NatureMedicine! It enables early QC&imputation at scale, visualization and downstream clustering & patient trajectory learning. https://t.co/PTqJ5P4C8X https://t.co/CJRIsM8jzi

Publish houses of brick, not mansions of straw Unfortunately, this breadth often compromises depth. Perverse incentives by linking acceptance to a pre­ordained result.

💯

Our tool 𝐫𝐞𝐭𝐫𝐢𝐞𝐯𝐞𝐫 can be used to identify candidate drug targets based on tumor RNA-Seq profiles from individual patients. A new version of the 🐕 manuscript is now out on BioRxiv: https://t.co/MnnSczlMLa

We are hiring a computational postdoc (3 years) working between @sangerinstitute and @embl together with @saezlab and @Muzz_Haniffa interested in generative modeling for skin diseases with large scale multimodal data. Apply here:

Seriously where did that plot go #phdlife #lablife #cellmates #thecellmatescartoons

Do you run functional assays? Wish you could get more results without having to scale? If you’re not using Prophet, you’re leaving potential on the table. (Warning: pitch not tweetorial)