
The CRISPR Journal
@CRISPRjournal
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Cutting-edge peer-reviewed research and analysis on genome editing for the global CRISPR community. EIC @crisprchef | Exec Ed @kevinadavies @liebertpub
New Rochelle, NY
Joined May 2017
Huntington's disease has been successfully treated for the first time, doctors tell BBC
bbc.co.uk
One of the most devastating diseases finally has a treatment that can slow its progression and transform lives, tearful doctors tell BBC.
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Join our colleagues @GENbio for "The State of Biotech" 4-hr virtual event, today at 11 am ET/8 am PT. Highlights include a keynote interview with George Church with our Exec Editor, @KevinADavies. Registration is free:
🎙️ Don’t miss @daphnezohar, @bradloncar & @cngarabedian of Biotech Hangout at #StateOfBiotech 2025 — Sept 24, 11:10 AM ET. Free summit hosted by @GENbio → https://t.co/R79K9887O8
#DrugDiscovery #LifeSciences #StateOfBiotech #BiotechHangout
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How We Built the First AI-Generated Genomes | Arc Institute
arcinstitute.org
Going from designing individual genes to complete genomes is an incredibly challenging problem. We have previously shown that the genomic foundation models like the Evo series can generate single...
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Deeply saddened by the loss of David Baltimore - a mentor, role model, and scientific giant who shaped so many of us. Most memorably, I was sitting next to David, a month after I started as a baby Assistant Professor, when I learned about CRISPR. His kindness and wisdom will be
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LAST CHANCE! TODAY, Vicky Smith, PhD, an expert in RNA biology, will provide a practical blueprint for enhancing mRNA quality using proven manufacturing strategies from TriLink’s 25+ years of expertise. REGISTER: https://t.co/iFIVmb6ZKh
@TriLinkBioTech
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For those who read our group's lncRNA study published last year, we have recently learned that the Cas13 library included some gRNAs that were not properly filtered for potential off-targets (as described in the Methods). While this does not affect the study's main conclusions,
🚨🚨🚨 Thrilled to share our newest study — identifying functional long noncoding RNAs using transcriptome-scale RNA-targeting CRISPR screens. 🔎🔎🔎 We hope this scalable approach will be helpful for folks who want to connect noncoding RNAs to phenotypes & diseases.
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Can You Afford a Cure? The Gene Editing Dilemma - interview with Alta Charo https://t.co/CJrv8WWwIr via @YouTube
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The 2025 @ArrigeOrg annual meeting is being held Oct 28-29 in Strasbourg (hybrid). Speakers include: Fabiana Arzuaga, Argentina Marina Cavazzana, France Kazuto Kato, Japan Kiran Musunuru, USA Michael Pepper, SA Pawel Luckow, Poland Julian März, Switzerland https://t.co/ZA5hQ6C6U1
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When it comes to deep learning for protein engineering, there is strength in simplicity. In a Preview piece @CellCellPress, we highlight work from @CaixiaGaoLab on using fixed-backbone sequence design to engineer genome editors with improved function. đź“„ https://t.co/NTjDMY4RP6
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Terrana Biosciences is looking to hire two Contract Research Associates to join our Delivery and Transformation team in Durham, NC.
job-boards.greenhouse.io
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Here’s a great interview of @davidrliu - the Co-founder of $BEAM & $PRME, in @GrinsteinJ “Behind the Breakthroughs” podcast in which they talk about CRISPR & Gene Editing & about the way that Prof. Liu’s groundbreaking modalities - Base & Prime Editing, are already saving lives!
When I first joined @GENbio in 2022, there was one name I kept hearing seemingly weekly: @davidrliu. David Liu's lab invented base and prime editing (gene editing tools now in 20+ clinical trials with early wins against sickle cell, leukemia, and more). In this episode of
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Our August issue is online now: A special issue on the proceedings of the 2025 Global Observatory for Genome Editing conference, including a post-conference statement from the organizers. https://t.co/sByfaj9u2W (Full access for a limited time.)
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When I first joined @GENbio in 2022, there was one name I kept hearing seemingly weekly: @davidrliu. David Liu's lab invented base and prime editing (gene editing tools now in 20+ clinical trials with early wins against sickle cell, leukemia, and more). In this episode of
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🚀 The State of Biotech 2025 — hosted by @GENbio. Wed, Sept 24 | 11 AM–3:30 PM ET. Free virtual summit with leaders in AI, CRISPR & biotech innovation. 🔗 https://t.co/OEEmo88D07
#Biotech #LifeSciences #Innovation #StateOfBiotech
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"A “Bare Hope of A Result”: The Second CRISPR Patent Appeal" -- Jacob Sherkow @jsherkow
https://t.co/eBh6pSDziw
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"Bacterial Expression System with Deep Repression and Activation via CRISPR-Cas9" https://t.co/6l8YHGRlxb Manuvera et al.
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New online: "Implementation of an Undergraduate Laboratory-Based Mammalian Genome Editing Course" https://t.co/Fr4qJYxsuM Guerra et al.
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Malaria Transmission Blocked by One-Amino-Acid Mosquito CRISPR Edit in FREP1 - new work from Ethan Bier's group in Nature https://t.co/qLVeagiSOm via @GENbio
genengnews.com
An allelic-drive system spreads malaria-blocking resistance in mosquitoes by altering a single amino acid in FREP1.
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🚀 Join CongLab @Stanford! We’re hiring postdocs to create lab-in-the-loop self-evolving AI agents, open benchmarks, to design, test & learn—advancing safer gene & cell therapies. Build on CRISPR-GPT, RNAGenesis model, Genome-Bench, for innovative medicines. #PostdocJobs
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A new #CRISPR Cures center, funded by $20M from @czi and led by @UrnovFyodor, will create 8 custom therapies for patients in the next 3 years. “Our goal is to aggressively walk the walk of CRISPR platformization,” Urnov told me. More in @endpts:
endpoints.news
Scientists seeking to make personalized gene editing therapies a reality for more people have launched a new initiative to develop cures for the rarest of diseases left behind by drug companies.
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