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Priya R. Banerjee Profile
Priya R. Banerjee

@BanerjeeLab_UB

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learning how macromolecular phase transitions program cellular functions. interested in single-molecule biophysics, disordered proteins and RNA.

Buffalo, NY
Joined February 2019
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@BanerjeeLab_UB
Priya R. Banerjee
3 years
How do RNAs phase separate without proteins? 💧💧🩸🩸.We are excited to share this story with you (preprint) "RNAs undergo phase transitions with lower critical solution temperatures". A longer thread will follow soon. @gable_wadsworth @PappulabWashU.
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@BanerjeeLab_UB
Priya R. Banerjee
6 days
Latest work on RNA condensation from the Banerjee lab, led by a superstar graduate student, Tharun Mahendran. Biomolecular condensates can enhance RNA percolation, leading to the emergence of multi-phasic RNA condensates.
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@BanerjeeLab_UB
Priya R. Banerjee
2 months
RT @taekjip: Check out this tour de force study by Sangwoo Park and his incredible team of collaborators. Biophysical properties of single….
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@BanerjeeLab_UB
Priya R. Banerjee
3 months
RT @ShorterLab: DNA binding and mitotic phosphorylation protect polyglutamine proteins from assembly formation: Cell
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@BanerjeeLab_UB
Priya R. Banerjee
3 months
RT @sshekhr: 📢Excited to share our new paper in @NaturePhysics : Cooperative hydrodynamics accompany multicellular-like colonial organizati….
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@BanerjeeLab_UB
Priya R. Banerjee
3 months
Happy to share our new preprint on small molecule mediated inhibition of aging of biomolecular condensates.
@tharun_selvam
Tharun Selvam Mahendran
3 months
In our new preprint, we study the physical aging of biochemically active condensates formed by an engineered Tau protein into disease-linked amyloid fibrils — and investigate whether small molecules can counteract this transition. @BanerjeeLab_UB .🧵1/3
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@BanerjeeLab_UB
Priya R. Banerjee
4 months
RT @Pha_Tran_Papers: Tunable metastability of condensates reconciles their dual roles in amyloid fibril formation.
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@BanerjeeLab_UB
Priya R. Banerjee
4 months
This observation led us to investigate the impact of sugar modifications on RNA condensation. We found that 2'-O-methylation (2'-O-Me) negatively regulates RNA condensation and promotes reversibility, suggesting that 2'-O-Me serves as a tunable switch for RNA condensation. 2/2.
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@BanerjeeLab_UB
Priya R. Banerjee
4 months
New preprint in collaboration with @jerelleaj!! We show that the 2’-OH group of ribose sugar plays a crucial role in RNA condensation, while its absence in DNA inhibits phase separation and percolation, a transition linked to condensate arrest. 1/2.
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@BanerjeeLab_UB
Priya R. Banerjee
6 months
RT @brangwynnelab: Excited to see this (cover) article on condensates come out in Scientific American. Nice quotes from me and many folks i….
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@BanerjeeLab_UB
Priya R. Banerjee
7 months
RT @potoyangroup: In collaboration with @BanerjeeLab_UB, we dive a little deeper into the microscopic interactions and sequence patterns sh….
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@BanerjeeLab_UB
Priya R. Banerjee
7 months
RT @LindorffLarsen: Meet the CALVADOS RNA model on bioRxiv or on 🦋
Tweet media one
Tweet media two
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@BanerjeeLab_UB
Priya R. Banerjee
8 months
RT @sesamedusa: “I still believe that finding mind lodged in biological matter is the most profound question that physics can pose. And tha….
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@BanerjeeLab_UB
Priya R. Banerjee
8 months
RT @potoyangroup: The #APS deadline for abstracts has been extended to Oct 31! This is an excellent venue to showcase your work if you work….
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@BanerjeeLab_UB
Priya R. Banerjee
9 months
RT @shaharsu: 📢New paper alert!! With @boothbylab @alexholehouse @fried_lab we take a look at how an entire proteome survives desiccation.….
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@BanerjeeLab_UB
Priya R. Banerjee
9 months
RT @MolecularCell: RNA-driven phase transitions in biomolecular condensates. In this review or our #RNA focus issue, @BanerjeeLab_UB and co….
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@BanerjeeLab_UB
Priya R. Banerjee
9 months
RT @MolecularCell: Our focus issue on RNA biology features reviews that explore the many faces of #RNA, diving into the processes mediating….
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@BanerjeeLab_UB
Priya R. Banerjee
9 months
RT @gable_wadsworth: Our review on RNA-driven phase transitions is up today at Molecular Cell! Check it out! @BanerjeeLab_UB .
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@BanerjeeLab_UB
Priya R. Banerjee
9 months
RT @brangwynnelab: How do you turn a condensate inside-out? Congrats to @sofiquinodoz & @jiang_lifei & co-authors on amazing study from our….
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@BanerjeeLab_UB
Priya R. Banerjee
9 months
Out today in @MolecularCell . Our review article highlights recent advances in ribonucleoprotein condensate biology, focusing on RNA-driven phase transitions. Efforts led by @gable_wadsworth and Sukanya Srinivasan.
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@BanerjeeLab_UB
Priya R. Banerjee
10 months
So glad to see this work in prints. RNA-based biomaterial are so exciting!! We @gable_wadsworth played a small role in this collaborative work with @JulieNguyenLab.
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