AmberAlhadeff
@AmberAlhadeff
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Neuroscience • gut-brain • food • she/her
Philadelphia, PA
Joined March 2018
I’ve been hosting the 7th International Melanocortin Meeting here in Cambridge with my co-organisers Roger Cone, Kate Ellacott and Anne White. Spectacular science! Here we are at the conference dinner! #obesityisnotachoice
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I’m so excited to share our preprint on how brainstem neurons sense and integrate multiple body signals during food consumption. We imaged 1000s of neurons across the lateral parabrachial nucleus (LPBN) in behaving mice.
biorxiv.org
Studies of body-to-brain communication often examine one stimulus or organ at a time, yet the brain must integrate many body signals during behavior. For example, food consumption generates diverse...
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Thrilled to join all the talented people at @MonellSc and work with @PennMindCORE! Great things to come! https://t.co/nFsoKPp6Nd
monell.org
Dr. Burger will lead a human neuroimaging laboratory that studies neural, behavioral, and perceptual responses to food and eating.
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The one and only @AmberAlhadeff visited @UBuffalo and gave a great talk about the power of hunger in the @UBNeurosci seminar series. #SSIBlingInTheWild @SSIBsociety @ub_cibr
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🚨 Exciting New Research Alert! 🚨 Our latest study, published in #NatureMetabolism, reveals how memory circuits in the brain drive intake of fats and sugars and impact body weight. 🍫🍟 Let’s break it down! 🧵
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Very good, concise summary of the gut-brain axis of communication and interoception https://t.co/97oqHFrhoi—%20to%20provide%20central open-access @CurrentBiology @AmberAlhadeff
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We found that in vivo peptide release and signaling gradually enhances the response of satiety-promoting hypothalamic neurons to each bite of food during a meal. These consequences of each bite take minutes to manifest, and could help explain why slow eating enhances satiety.
I am thrilled to share the published version of our study on how neuropeptide signals regulate feeding in the hypothalamus! We imaged endogenous peptide signals in subcellular compartments during behavior. Below is an updated summary: https://t.co/ONFDccZXc5
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I am thrilled to share the published version of our study on how neuropeptide signals regulate feeding in the hypothalamus! We imaged endogenous peptide signals in subcellular compartments during behavior. Below is an updated summary: https://t.co/ONFDccZXc5
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HAPPY to share our new paper! Are there specific neurons for food need (hunger) and food motivation (appetite)? Computational modeling and neural activity recording dissociated these two neurons.THX to @HyungGoo_Kim @kyusik_kim_ @SerenaYounghee @bbbining
science.org
Experimental and computational methods elucidate the neural substrates of need and motivation in hypothalamic neurons.
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Come explore emerging research in brain-body communication @KeystoneSymp Interoception: Neural Sensing and Control of Organ Function, this April in Seattle! https://t.co/l6KIgl5sSd
#KSInteroception25
keystonesymposia.org
Join us at the Keystone Symposia on Interoception: Neural Sensing and Control of Organ Function, April 2025, in Seattle, with field leaders!
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Huge congrats to @TheErinCalipari on the Waletzky Award and @AmberAlhadeff on the Trubatch and to all the other winners! So well deserved!
Congratulations to the 2024 SfN award and prize recipients! Their passion, innovation, and commitment to advancing the understanding of the brain are shaping the future of neuroscience. SfN looks forward to celebrating their achievements at #SfN24! Learn more about the
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Monell Chemical Senses Center. These are the people who truly understand my deepest questions. This is the reason I chose the life of a scientist, to chat forever about nerdy things and making special friends. @AmberAlhadeff @GdeLartigue @dietrich_mo
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Be mindful about axon collateralization! We have changed some experimental strategies based on this discovery. Proud to have the cover image for this journal issue and also a “Featured Article” designation! Happy times. https://t.co/yKQKKPvjSw
jneurosci.org
Neurons in the caudal nucleus of the solitary tract (cNTS) and intermediate reticular nucleus (IRt) that express the glucagon gene ( Gcg ) give rise to glucagon-like peptide 1 (GLP1)-immunopositive...
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Specific neurons in the brain’s zona incerta play a crucial role in the early social interactions of an infant and its mother, building their bond and reducing stress, according to a new Science study in mice. 📄: https://t.co/YYuwqdo2hM
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So happy to share our new work that is now out @sciencemagazine: We show how neurons in the mouse zona incerta (ZI) modulate infant social behaviors and learning. This work was led by the AMAZING graduate student Yuexuan Li @yuexuan_li. 🎉 https://t.co/hNnNZmZVEw
#ScienceResearch
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Discovery of a set of "I feel good with mommy" neurons in the zona incerta of mouse pups. A superb finding by @dietrich_mo that opens a new fields of inquiry on infant social behavior circuits! Bravo!... Science
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#NatMetabPicks | In @Nature led by @AmberAlhadeff (@Penn): The neural circuits in the hindbrain linking satiety and aversion are shown to be separate, raising the possibility of developing #obesity drugs without the side effects of nausea and vomiting. https://t.co/xijiytNziV
nature.com
Nature - The neural circuits in the hindbrain that link satiety and aversion are shown to be separate, raising the possibility of developing obesity drugs without the common side effects of nausea...
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“There’s always been a mystery about the relationship between being full and being nauseous,” said neuroscientist @AmberAlhadeff How are we solving this mystery? Read more in this story from @whyy about the most recent scientific discovery out of Monell https://t.co/kTK0LzoiVS
whyy.org
The study focused on semaglutide, the active ingredient in drugs such as Wegovy and Ozempic. It is known to reduce feelings of hunger while increasing feelings of nausea.
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I am super honored to have been invited by the student committee on neurometabolism! Can't wait to visit Quebec City and meet everyone. It's going to be "hyper chouette"!
The 8th conference of the 2024 #ObesitySeminarSeries of @IUCPQ will be a joint event with @SCiNeurometab 🤩. We are excited to welcome @GdeLartigue from @MonellSc in beautiful Quebec City to discuss Gut-Brain circuits!!
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Postdoctoral Position in Resolution of Inflammation. We are seeking for a recent PhD graduate to join our group at Yale! Please see the link for all details.
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