Archimedes
@AlphaTrader00
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Thinker. Investor. Satire. Advocate of the Ladder-adjusted risk premium
PNW
Joined October 2016
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어린이날
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Pinned Tweet
I'd really like to know who bought 96 $SIVB 17 March 23 $150 P's on March 6 for $0.01. They're trading around $64.30 right now.
$96 into $617,184
aka a +642,900% gain
Has anyone ever seen a bigger % options pay off?
I sure haven't
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429
3K
@ItsVeryJerry
Unfortunately,
#NuVariant
looks much, much worse than the
#DeltaVariant
Tragically, new
#COVID19
cases are likely to go parabolic in South Africa over the next several weeks/month(s)
SA new cases (per million) should pass Germany and UK very quickly
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@JackFarley96
Hi Jack,
If you're going to post $BAC unrealized losses on debt securities in the format you did, then you should also mention that $87B of the $113B is in HTM Agency MBS with 99.997% due after 10 yrs & another $20B in HTM Treasury and government agencies 96.26% due after 5 yrs
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These $SIVB calls went off 40 seconds before the close on 03/06 and were routed through Nasdaq Global Market (UQ)
👀The plot thickens 👀
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@0bj3ctivity
mRNA bivalent BA.5 boosters failed to keep up with mutations.
Not a shock to anyone who has consistently followed the science opposed to following the science until it provides your desired outcome then you close the book and stick your head in the sand.
@DrEricDing
The Swiss recently said that Pfizer's new bivalent booster data is insufficient for BA.4/5 variants
If there's no clear evidence it works on
#BA4
#BA5
, what are the chances it will work on the more evasive
#BQ1
#BQ11
variants?
Nuvaxovid boosters fix this
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Bivalent mRNA boosters failed even before they started, because their antigen is too narrow and companies can't update them fast enough & get ahead of SARS-CoV-2 mutational fitness.
Novavax's vaccine has much higher efficacy on emerging variants than mRNA
"Overall, vaccination with or without prior SARS-CoV-2 infection and even booster shots of novel bivalent (WA1-BA.5) mRNA vaccines did not confer protection against any of the four Omicron XB and BQ subvariants" 1/x
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@pieterstreicher
Advocating for no restrictions, claiming cases have peaked, and making a prediction on deaths on day 17 since the virus received a PANGO lineage is both foolish, harmful, and counterproductive to harness actionable time in a pandemic.
Are you a virologist or epidemiologist?
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@Gab_H_R
The BA2 sublineages & other variants are most concerning. These fit variants are outcompeting many of our best treatments (sotrovimab). The next US wave started last night (official figures).
We're running out of time to get next gen therapeutics ready
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#Humanigen
's
#lenzilumab
is now the
#1
#COVID19
treatment in the world!
"Lenzilumab improved the relative likelihood of survival without need for invasive mechanical ventilation (IMV) by 54%, achieving the primary endpoint of the Phase 3 study."
$HGEN
FDA Approves Initiation of Humanigen Phase III Study of Lenzilumab in COVID19 Patients.
$HGEN has 3 yrs exp studying GM-CSF neutralization and cytokine storm mitigation. This is 1 area of interest to keep a very close eye on in terms of
#COVID19
research
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"FIG.3. Myocarditis after COVID-19 vaccination stratified by vaccine type. The risk of myocarditis was highest in the Moderna vaccine group." $MRNA
#Myocarditis
risk was also high in the Pfizer $PFE vaccine group
Novavax $NVAX showed no myocarditis risk
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Please pray for all the people that started investing in the last 9 months, were up +200%, and thought this whole thing is too easy
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Great to see $NVAX receive FDA authorization for its updated COVID-19 booster dose today
I'd like to thank all the people who fought tirelessly on the consumer advocacy front to see Novavax available for widespread use.
@Justanewsletter
@Friesein
& others
New global SARS-CoV-2 EG.5 Eris wave
Possible $NVAX short squeeze, currently $7.35
- Chart primed
- 42.9% short float
- Borrow % increasing
- S3 squeeze risk 100/100
- Call volume/sweeper flow
- Sept booster roll out (NVAX>MRNA)
- Days to cover rapidly increasing, now at 8.15
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$ENVX - What adoption rate would Apple Vision Pro AR/VR/XR headset have with multi-day battery life instead of 2 hours?
First wearables to solve battery life challenges, wins.
Cough, cough $AAPL, $META, Samsung, etc
I'm curious what battery will be powering the new $META Quest 3 VR headset?
Could it be $ENVX?
@AlderLaneEggs
@joceyreyes209
@fleckcap
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I'm going to repost this groundbreaking
#COVID19
medical breakthrough,
#lenzilumab
, from the world's top hospital system
@MayoClinic
every
single
day
until newly hospitalized COVID-19 patients have access to the type of medical care they deserve
@POTUS
@VP
@WHCOVIDResponse
From cancer to
#COVID19
: With a united science and medical infrastructure,
@MayoClinic
researchers raced through the scientific steps to repurpose a
#CancerTreatment
into a
#ClinicalTrial
for
#COVID19treatment
in less than a year
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Quickest Real Estate Bull to Bear Market in history?
Canada 2021?
Today was a move for the ages for Canadian interest rates. But there's still time to catch lenders napping and pick off some of the lowest fixed rates of all time.
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If you've ever wanted a lesson in shorting stocks with parabolic tops, here's a 🧵
This is how I nearly top ticked the generational $SMCI short
$SMCI Put options are up 5,000%, 10,000%, 15,000% and more today
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New global SARS-CoV-2 EG.5 Eris wave
Possible $NVAX short squeeze, currently $7.35
- Chart primed
- 42.9% short float
- Borrow % increasing
- S3 squeeze risk 100/100
- Call volume/sweeper flow
- Sept booster roll out (NVAX>MRNA)
- Days to cover rapidly increasing, now at 8.15
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FDA Approves Initiation of Humanigen Phase III Study of Lenzilumab in COVID19 Patients.
$HGEN has 3 yrs exp studying GM-CSF neutralization and cytokine storm mitigation. This is 1 area of interest to keep a very close eye on in terms of
#COVID19
research
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7
42
I never could have guessed that $HGEN would ever be the
#1
holding in the SPDR S&P Biotech ETF, $XBI
But here we are!
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Tomorrow's $HGEN
#COVID19
event should be exciting. It's not everyday that you get to hear from a CAR-T expert and there may be some goodies discussed about
#lenzilumab
's dual-action (T-Cell) mechanism of action.
#DeltaVariant
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Beyond auto correlation being the 800-pound madoff in the room, there is also the compelling data originally between
#Tether
and
#Bitcoin
and more recently Tether and alt coins, on top of suspected illegal trading and fraudulent exchs
@JamesGRickards
@Bitfinexed
@Silver_Watchdog
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10
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The CEO of $HGEN just acquired 652,640 stock options at the exercise price of $16.07, for a total of $10.5 million, through an executive compensation program.
Talk about a vote of confidence for a co trying to solve the COVID19 pandemic/patient mortality
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Today, Vanguard Group's 13F showed an increase in it's share holdings of $HGEN by 13.22% for a total of 1.8 million shares.
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Imagine turning $96 into over $1,000,000 in 1 week?
The $SIVB stock is halted right now, but by using the last pre-market trade of $39.40, and assuming these 96 call contracts weren't closed out yesterday, they could be worth
$1,061,760 today
aka a 1,105,900% gain
Life changer
I'd really like to know who bought 96 $SIVB 17 March 23 $150 P's on March 6 for $0.01. They're trading around $64.30 right now.
$96 into $617,184
aka a +642,900% gain
Has anyone ever seen a bigger % options pay off?
I sure haven't
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On the Jefferies Investor Call
$HGEN has just guided the production of 60 bulk drug substance lots in 2021
That is a whole lot of
#lenzilumab
product! Well over 300k doses!
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This new
#GautengVariant
is now known as B.1.1.529
"A new covid variant with an “extremely high” number of mutations and which could escape vaccines has been identified in three different countries."
South Africa, 3.6% positivity rate & climbing quickly!
@F4DE2BL4CK
@TradeTraders
@SkyNews
@sunchartist
This new
#GautengVariant
/ SARS-CoV-3, is alarming!
The breadth of conserved Spike mutations is very concerning - especially the double Δ's near the FCS (N679K, P681H) & in the NTD, RBD, RBM, + up to L981F
Non-Spike mutations also noted: NSP_, E, M, N
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Congrats $EOSE baggies.
Now is when the actual challenging work begins. What a great opportunity
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You know things are getting bad in Toronto when car dealerships are going into receivership.
#ToRE
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Back in mid April, I said $HGEN is way ahead of the pack on GM-CSF targeting therapeutics for
#COVID19
Almost 2 months later, heres the
#Lenzilumab
compassionate use data which shows exactly that
Excited to see Phase 3 potential registration study data!
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I'm very pleased with the small and nimble $HGEN's ability to forge & secure so many high quality partnerships across the Biotech supply chain.
IMO the ability to develop these partnerships may be a key determinant during the EUA application assessment process by the FDA.
We are pleased to announce our partnership with
@EVERSANAcompany
to support the commercialization of
#lenzilumab
.
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$HGEN recently passed it's +500 patient P3 randomized, double-blind, placebo controlled clinical trial, & has the world's best data on reducing the likelihood of hospitalized
#COVID19
patients getting ventilated & dying
#lenzilumab
is ready to save lives!
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Now would be a good time to research therapeutics for hospitalized
#COVID19
patients amid this new global
#DeltaVariant
wave!
If you want a head start, $HGEN's lenzilumab has the world's best data out of any therapeutic for hospitalized covid19 patients
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It's been a long journey, but we did it!
$HGEN's
#lenzilumab
is now the world's
#1
#COVID19
therapeutic
Next stop is fixing CRS and neurotoxicity in
#CART
and more
FDA Approves Initiation of Humanigen Phase III Study of Lenzilumab in COVID19 Patients.
$HGEN has 3 yrs exp studying GM-CSF neutralization and cytokine storm mitigation. This is 1 area of interest to keep a very close eye on in terms of
#COVID19
research
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@fitterhappierAJ
You're way ahead of the curve
@fitterhappierAJ
I've been banging on the table about
#Omicron
positive patients getting reinfected with either Omicron or an Omicron sublineage such as
#BA2variant
. Plus the risk from the next variant that becomes dominant
"Omicron variant is associated with substantial ability to evade immunity from prior infection" with reinfection risk 2.39x vs 1st wave.
Getting ahead of myself here, but what is the reinfection risk of a positive Omicron patient getting reinfected with a
#Omicron
sublineage?
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$HGEN plans to:
-Submit an EUA application to the FDA during May 2021
-Initiate a rolling CMA submission to UK before the end of Q2 2021
-Submit for CMA to the EMA for EU
-Review the possibility of similar submissions for approval or compassionate use in other countries worldwide
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@Keubiko
@IHOP
Do you remember the time I data mined 1038 days of $USDT and $BTC market data
and found a Pearson's r = .805 suggesting auto correlation and potential manipulation?
Then
@nytimes
ran a story on this topic 152 days later
Beyond auto correlation being the 800-pound madoff in the room, there is also the compelling data originally between
#Tether
and
#Bitcoin
and more recently Tether and alt coins, on top of suspected illegal trading and fraudulent exchs
@JamesGRickards
@Bitfinexed
@Silver_Watchdog
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@unusual_whales
Thanks for the $QQQ flow
@unusual_whales
Markets are overdue for a bounce (however short-lived)
$QQQ 292 C +101%
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@in_retrotech
Still looks too baggy for me, even post this $398.6M LPO loan. But I wish the $EOSE bulls the best of luck going forward
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$HGEN
#Lenzilumab
is the world's best
#COVID19
treatment- Full Stop!
Lenz improved the likelihood of SWOV by
-54% in the mITT population p=0.041
-90% in the ITT population p=0.043
-92% in subjects who received both corticosteroids & remdesivir p=0.0067
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9
28
Below: An English version of a German conversation entitled "A biomarker as a new beacon of hope" with
@BecherLab
&
@DLF
$HGEN's
#Lenzilumab
has the world's largest IP estate on GM-CSF inhibition
Lenz halts
#COVID19
disease progression in
#LIVEAIR
study
#Coronavirus
#COVID19
Hoffnung auf frühzeitige Erkennung schwerer Krankheitsverläufe mittels Analyse des Botenstoffs „Granulozyten-Makrophagen-Kolonien-stimulierender Faktor“ (kurz GM-CSF).🙏🏽👍🏻
Ein Biomarker als neuer Hoffnungsträger -
@BecherLab
via
@DLF
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Archimedes Lever Portfolio: new long
$GRTS's Universal Heterologous Prime/Boost Immunization Platform, via leveraged AI is compelling. IMO they will dominate the 2nd gen vaccine space with N & ORF3a gene region targets with validated CD8+ T-Cell epitopes
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The Phase 3 results, "along with data regarding additional endpoints and further analysis from the study, support the submission of applications for emergency use authorization to the U.S. FDA & conditional marketing authorization in the UK & the EU"
$HGEN
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On April 1 22, most Americans thought that
#COVID19
was over after a few months of declining cases from the winter Omicron wave
With a bit of work + a bunch of luck, somehow my new case growth estimate, shown by this red freehand curve, had a Pearson's r ~ 0.97 (est) last month
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Lenzilumab ontop of remdesivir improved survival w/o the need for mech ventilation by 91%. In <85 yo patients in early inflammation, Lenz ⬆️the odds of ventilator-free survival by nearly 3-fold
#Steroids
⬆️ infection risk, $HGEN's Lenz could be a
#SteroidReplacement
for
#COVID19
#lenzilumab
feature in
@Reuters
"In a paper posted on Wednesday on medRxiv ahead of peer review, the research team reported that patients in the lenzilumab group had a 54% better chance of surviving without needing mechanical ventilation."
Read more:
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Anyone here good at Game Theory?
$HGEN "to initiate registrational study with the 3 approved CAR-T therapies in DBDCL"
$GILD's Yescarta
$NVS's Kymriah
$BMY's Breyanzi
just in DBDCL CAR-T
Broader CAR-T market is much larger and includes several other bulge-bracket pharma co's
We are pleased to report positive data from the Phase 1b portion of ZUMA-19 evaluating the efficacy and safety of
#lenzilumab
in patients treated with CAR-T in diffuse large B-cell lymphoma (DLBCL):
Read More:
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The herd is so thin, there's no one left!
A $HGEN EUA will save thousands and thousands of lives in this brutal pandemic.
tic.toc
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This guy brings up some great points!
$HGEN's
#lenzilumab
can bend the hospitalization and death rate lower than any other drug in the world for newly hospitalized
#COVID19
patients.
How much longer before patients have access to this life saving drug?
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Clinical trial shows greater response from Black Covid patients. The trial treated this group w lenzilumab & found they demonstrated a 9-fold increase in their chances of survival compared with 2.5 times for the overall population
$HGEN
#HealthEquity
#BLM
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This guy gets it 👇
$HGEN's Lenzilumab halts early
#COVID19
disease progression in hospitalized patients better than any other drug on or not yet on the market.
$HGEN Starting to think it has decent chances with EMA. Seems to work well with early intervention among hospitalized subjects (before CRP spike)
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Jerry gets it👇
$HGEN's GM-CSF inhibitor lenzilumab halts
#COVID19
disease progression in newly hospitalized patients better than any other COVID19 therapeutic in the entire world. Period. Full stop.
It's painful waiting this long for the inefficient market to wake up
$HGEN Recent study has identified features linked to severe COVID-19.
High amounts of viral RNA (vRNA) in plasma, which has been associated with greater severity and worst outcome
Several cytokines were positively correlat...
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When the majority of the stock market $SPY $QQQ is red, I sometimes check out what stocks are on SSR and hunt for any quality names in that pile
I only found a few that have strong underlying fundamentals, upcoming catalysts, volume, and are green
$HGEN
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Will $HGEN's GM-CSF inhibitor
#lenzilumab
be the key to solving CRS and ICANS issues that are holding back CAR-T therapy from wide spread adoption in immuno-oncology?
The Phase 3 SHIELD study will answer this very important question
#Humanigen
announces abstract at
#ASH
describing Phase 3 SHIELD study to confirm whether lenzilumab can improve the toxicity and tolerance of all commercially available CAR-T for non-Hodgkin lymphoma while maintaining or improving efficacy and durability of response
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@DGBassani
I don't know you nor will I likely ever meet you but please do know that there is an ounce of empathy and compassion, from a complete stranger, floating around the ether - and God willing may it eventually find you and your family.
I'm so sorry for your loss
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I wish more people knew how valuable this sentence is
"The modulation of intrinsic pathways is not due to an off-target effect & provides additional mechanistic rationale for the improved anti-tumor activity observed with GM-CSFKO CAR-T"
They eventually will, post $HGEN buy-out
We are pleased to announce that granulocyte macrophage-colony stimulating factor (GM-CSF) gene-edited CAR-T data will be presented at the International Society for Cell & Gene Therapy (ISCT) 2021 Annual Meeting on May 28th from 11:30AM – 1:00PM ET.
#HGEN
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Can’t believe $ALAR is up over 1,100% since I first mentioned and bought it around $2.40 only 7 months ago.
Not everyday you get a 11 bagger in this market.
I’d love to hear other peoples big swing trades and what their strategy was for holding onto and taking profits
@smantel
Nice to see $ALAR looking strong today at $3.00
Up 25% from the $2.40 accumulation zone
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@StuartTurville
@Mike_Honey_
@EricTopol
Great work Dr. Turville, thank you for this paper!
This is likely the most challenging part of the COVID19 pandemic, tackling multiple transmission pathways including TMPRSS2-independent and cell to cell transmission on top of the standard S-ACE2/TMPRSS2
@NToola9
@fitterhappierAJ
@fitterhappierAJ
Where do we even go from here...?
"Upon infection, viral RNA, subgenomic RNA, viral protein...can be detected in the T cells. Furthermore, we show that the infection is spike-ACE2/TMPRSS2-independent through using ACE2 knockdown or receptor blocking experiments"
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The cat is out of the bag
Is $HGEN worth 5-10 billion?
@RousingSpring
@ItsVeryJerry
So we all know that Lenzi stops CRS, and potentially stops NT in CAR-T.
This, however, is extraordinarily positive pre-clinical evidence that GM-CSF ligand targeting (Lenz) actually INCREASES EFFICACY of CAR-T therapy by encouraging the proliferation of T Cells!
$HGEN
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The B.1.617.1 variant is 6.5-fold more resistant to neutralization by sera from
#COVID19
convalescent, & by 7-fold in both the Moderna & Pfizer vaccinated individuals
#VariantAgnostic
therapeutics like $HGEN are needed now as we await for vaccine boosters
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New and active condo listings in the GVA are exploding, devastating the last area of strength in the market
New Listings:
Van - 1340 +75%
Richmond - 482 +62%
Burnaby - 489 +96%
Active listings:
Van - 3058 +213%
Richmond - 1177 +225%
Burnaby - 921 +209%
@SteveSaretsky
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$HGEN's
#lenzilumab
halts
#COVID19
early disease progression better than any other treatment I've seen in the entire world. Period. Full stop.
HR:8.33...
This is front page news!
Name a better way to turn this pandemic into an endemic - I'll wait
@timb224
@humanigen
@GENbio
Almost 12 months to the date!
Emerging data suggests CRP levels can be used to determine which
#COVID19
patients and at what times, $HGEN's
#Lenzilumab
treatment may provide the greatest clinical benefit
Groundbreaking efficacy (SWOV)
CRP<41mg/L, HR:8.33
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@ripster47
It's good to hear what twitter users are thinking about
#DeltaVariant
plays
But I'd also ask what did the world's best hospital discover?
Mayo Clinic on the world's best
#COVID19
therapeutic for newly hospitalized patients 👇
$HGEN, works on all variants
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Hello Day 3
Reposting this groundbreaking
#COVID19
medical breakthrough,
#lenzilumab
, from the world's top hospital system
@MayoClinic
every
single
day
until newly hospitalized COVID-19 patients have access to the type of medical care they deserve
@WhiteHouse
@WHCOVIDResponse
From cancer to
#COVID19
: With a united science and medical infrastructure,
@MayoClinic
researchers raced through the scientific steps to repurpose a
#CancerTreatment
into a
#ClinicalTrial
for
#COVID19treatment
in less than a year
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$HGEN sentiment is rising rapidly on twitter and reddit, as seen in this trending post on
@wsbmod
's wallstreetbets
Humanigen was the 3rd fastest rising (sentiment) stock last week!
I don't think HGEN will remain unknown for much longer
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Back in Feb 2020 nobody outside the biotech community knew $NVAX. Within a few months due to its incredible technology & partnerships the Co blew up to become a household name. Is $HGEN next?
NVAX: 3rd fav trade of yr
Then:$7.95
Now:$268.3
32,748% return
Novavax’ Preclinical NanoFlu Data Published in Vaccines; Details Structural Basis for Broadly Neutralizing Immunity
$NVAX
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5
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NIH's ACTIV-5/BET-B trial saw 2 clinical trial sites move to recruiting today: Great Lake Clinical Trials of Chicago, Illinois and Penn State Health Medical Center of Hershey, Pennsylvania.
The first 2 international sites were added. Seoul, Korea
$HGEN
1
6
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Telcon RF Pharmaceuticals announced on [Sept] the 8th that it will start the domestic clinical trial [in Korea] of
#Lenzilumab
, a COVID-19 treatment, jointly promoted with KPM Tech
If the domestic clinical trial passes, a domestic import product license may be applied for
$HGEN
1
7
23
At the recommended Phase 2 dose, lenzilumab in combination with CAR-T, demonstrated a 100% objective response rate (ORR) and no severe cytokine release syndrome or severe neurotoxicity
-Lenzilumab reduced IL-6, CRP, ferritin, MCP-1, IL-8, and IP-10
$HGEN
1
2
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@humanigen
@FinancialTimes
$HGEN's lenzilumab looks to be a life-saver for minorities, inc African Americans
I appreciate how the Phase 3 LIVE-AIR study enrolled more Hispanic & African Americans in the study than are represented in the US census & less White (non-hispanic)
#HealthDiversity
#HealthEquity
0
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$HGEN's fast-tracked CMA submission review for their
#COVID19
treatment lenzilumab should be wrapping up in the next few months in the UK
UK ANNOUNCES AN EXTRA 5.4 BILLION POUNDS FOR NHS COVID RESPONSE OVER NEXT SIX MONTHS
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Only in 2021 can anonymous twitter accounts that no one has ever heard of be able to out-research "professional analysts", out-complete "biotech gurus" and out-do "professional journalists."
$HGEN might just beat
#COVID19
and fix
#CART
all before the kettle comes to a boil
So strange that they didn’t want to include patients who didn’t get the drug in the readout.... 😆
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Day 4
$HGEN
I'm going to repost this groundbreaking
#COVID19
medical breakthrough,
#lenzilumab
, from the world's top hospital system
@MayoClinic
every
single
day
until newly hospitalized COVID-19 patients have access to the type of medical care they deserve
@POTUS
@VP
@WHCOVIDResponse
0
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1
1
22
$HGEN with a late AH 411,810 share print..
Worth $7,746,146
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2
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$HGEN flex
As vaccination rates decline and cases are increasing hospitals are running out of supply for
#COVID19
treatment drugs. Now more than ever
#Humanigen
would like to highlight the need for treatments as hospitalization rates continue to rise.
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Assets seizures are now on the table.
2019 is the year of the firesale in
#VanRE
Circuit breaker, limit down, no bid
4
4
23
@Mtnbiker15
@nzm8qs
@PeacockFlu
The mix of virulence & transmissibility of B.1.1.529 is what concerns me. Over the past few days, many people suggested that it's both too early to comment on
#B11529
and unlikely that it outcompetes delta. My point is, I think they're dead wrong & data is accumulating by the min
1
0
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Going to repost this groundbreaking
#COVID19
medical breakthrough,
#lenzilumab
, from the world's top hospital system
@MayoClinic
every
single
day
until newly hospitalized COVID-19 patients have access to the type of medical care they deserve
Day 2
@WhiteHouse
@WHCOVIDResponse
From cancer to
#COVID19
: With a united science and medical infrastructure,
@MayoClinic
researchers raced through the scientific steps to repurpose a
#CancerTreatment
into a
#ClinicalTrial
for
#COVID19treatment
in less than a year
5
15
58
1
5
22
9 of the 10 drugs selected by the EU are produced by Big Pharma companies, with an average market cap of $200 Billion
The 10th drug is $HGEN's
#Lenzilumab
which is a US microcap worth only $0.4 Billion
$HGEN would need to 20x just to catch up to the 2nd smallest co on this list
1
4
22
$FRC M&A?
Bloomberg consensus FRC 22 TBVPS $74.19
$3.894B in non-agency unrealized HTM losses over 02/13/23 s/o 186,218,729 =$20.91
First Republic Bank current share price $32.38
Assumptions
1.5 P/TBV = $79.92, (146.82% potential upside)
2 P/TBV = $106.56 (229.09% pot. upside)
7
4
23
Time for a repost
I.Won't.Stop
$HGEN
The support and need for variant-resistant
#COVID19
therapeutics should be equal to or > than vaccines at this present moment.
I've been saying this for almost 10 months to the day, and won't stop saying this until it happens.
$HGEN
#lenzilumab
GM-CSF
0
2
15
1
2
22
Step 1: Consult wifyo Rabbi, Financial Advisor or Twitter G/FURU
Step 2: Wait for top (on $SMCI in this example)
Step 3: Size in
Step4 : Bank
Step 5: Don't forget to shitpost on fintwit/X
End of 🧵
Share this & educate others
1
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Agreed on the ruxolitinib data
In a years time, we will probably all look back on the Thwaites GM-CSF paper as the tipping point in solving COVID19 immunopathogenesis.
$HGEN's lenzilumab is so far ahead in the GM-CSF inhibitor space (IP) that there really isn't any competition
1
4
22
“Conducting this trial in the midst of a worldwide pandemic was no easy feat, but such times demonstrate how important medical research is to ensure we can advance medical care in a safe way for all patients,” - A. Zuckerman, MD, MPH, an infectious disease physician at DHMC
$HGEN
#lenzilumab
article from
@DartmouthHitch
, one of the various trial centers for the study of lenzilumab in patients hospitalized with
#COVID19
.
1
10
51
1
2
21
$40 million draw on $HCG liquidity position going into a stressful weekend.
Could be an interesting mon morning?
0
3
20
If approved, lenzilumab could serve a set of hospitalized patients who have proven difficult to treat with other COVID-19 drugs. Researchers have tested other drugs designed to tamp down immune responses, including Roche’s Actemra & Sanofi’s Kevzara, with mixed results.
$HGEN
We welcome the news of
@humanigen
’s positive top-line clinical trial results in their Phase 3 study of lenzilumab in hospitalized patients with COVID-19.
#covid19
#covidtreatment
0
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33
1
2
20
This paper and these findings should be on the front page of every newspaper, magazine, and website all over the world!
These folks may have just solved
#COVID19
pathogenesis by identifying the role that GM-CSF plays in COVID-19 disease progression and mortality.
Top class!
A new
@SciImmunology
study of 471 patients with a wide spectrum of
#COVID19
reveals key inflammatory and thrombotic factors that characterize severe disease. Led by a UK
#coronavirus
consortium, including
@ImperialNHLI
,
@EdinUni_MeetCIR
,
@LivUni
:
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