Alexandre TROTIER
@ATROTIER
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Postdoctoral Fellow researching on Alzheimer's disease at the Paris Brain Institute @InstitutCerveau . Ex-PhD student at @CURAMdevices & @Biggs_Lab .
Paris, France
Joined May 2013
Happy to see my PhD work out today in @AdvSciNews ! https://t.co/F1HlyQet9i Thanks to all involved @EnricoBagnoli2 @TomaszWalski @JudithEvers2 @EugeniaPuglies1 @csgontour @unafitzg @Biggs_Lab @CURAMdevices
advanced.onlinelibrary.wiley.com
This study reveals that peri-electrode void progression is mediated by fluid flow shear stress, which can be replicated using parallel-plate flow chambers to induce neuroelectrode glial scarring in...
Did you know that breathing creates microscale motion of the brain which can inflame the tissues around an implanted neural device, causing failure? Our latest paper sheds light on the mechanobiology of this process. @ATROTIER @CURAMdevices @Bio_Eng_NUIG
https://t.co/3UVRCptBkH
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Organelle IP goes tagless.
New paper from @EstherSammler et al presents ‘tagless LysoIP’ method, which enables enrichment of lysosomes (using TMEM192) directly from clinical samples & human cell lines; Metabolic profiling shows accumulation of glycerophosphodiesters in CLN3 patients https://t.co/5GvCzNM5MH
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I would like to thank the Alzheimer Foundation @StopALZ for giving me the opportunity to present my work on wake slow waves in older adults with memory complaints 🙏
🔬✨Pierre Champetier explore le potentiel des ondes lentes sur l’EEG de repos comme indicateurs précoces de la maladie d’Alzheimer. Son étude montre que l’amplitude des OL augmente avec la charge amyloïde : une piste prometteuse pour détecter la maladie dès ses premières étapes
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Congrats Axel and all ! @InstitutCerveau @StopALZ
Félicitations aux 3 lauréats du prix des Meilleurs Posters des Rencontres 2024 ! Axel LEGRAND, Fanny EYSERT et Aure SORASSO-BLUEM.
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Félicitations aux 3 lauréats du prix des Meilleurs Posters des Rencontres 2024 ! Axel LEGRAND, Fanny EYSERT et Aure SORASSO-BLUEM.
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Very proud of my brother Brendan for running the Dublin City Marathon in honour of my son, Oisín, who was diagnosed with a fatal brain tumour 10yrs ago. Support for @braintumourIRL welcome 👇
Running the Dublin Marathon in memory of my nephew Oisín and to raise funds for Brain Tumour Ireland. This week is Brain Tumour Awareness Week To all my family's utter devastation, 10 years ago this month, my nephew Oisín was diagnosed with an incurable brain tumour 1/4
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We have multiple Postdoc Openings: Reach out to us & let's meet up at #SfN. https://t.co/YbB9hXEjGe
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Alzheimer’s disease originates with the prion-like misfolding and seeded aggregation of Aβ.
science.org
Similarities to molecular mechanisms underlying prion diseases may help to refine Alzheimer’s disease therapies
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The daughter of a scientist and a supporter of diversity in STEM, Harris’s prospects have stirred optimism among scientists.
nature.com
Nature - The daughter of a scientist and a supporter of diversity in STEM, Harris as a potential candidate has stirred optimism among scientists.
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If interested in applying for a PhD fellowship in my lab to study immunoengineering please get in touch!
Call for applications to our @MedDevDoc Doctoral Training programmeis now open, offering unparalleled opportunities for research training, career development & knowledge exchange across borders and sectors. For more information see https://t.co/whFWyWgAWe Closes 17th Aug 2024!
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One could argue that fluid efflux is more rapid during wake in response to mechanical pumping caused by locomotion amd increased heart rate.
A system of fluid-filled channels is thought to help flush waste from the brain. New research challenges the prevailing idea that this clearance ramps up during sleep. https://t.co/bWbCHXT756
@NewsfromScience
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1st we looked at frequency, then amplitude, temporal patterns, waveform shape, waveform shape and frequency, and dynamic biomimetic icms trains. Here, we examine how metabolism and neurovascular coupling during and post ICMS shape depression and SIDNE https://t.co/jnXID40VyX
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Piezoelectric modulation of microglia activity for glioma immunotherapy: Our latest paper on Advanced Healthcare Materials. https://t.co/N2d0C9Ndm1
@IITalk
@AdvSciNews
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Piezo1 regulates meningeal lymphatic vessel drainage and alleviates excessive CSF accumulation @NatureNeuro
nature.com
Nature Neuroscience - The authors find that Piezo1 stimulation enhances meningeal lymphatics and boosts CSF drainage to treat hydrocephalus and ventriculomegaly, showing promise in Down syndrome...
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Astrocytes are the source of TNF mediating homeostatic synaptic plasticity
jneurosci.org
Tumor necrosis factor α (TNF) mediates homeostatic synaptic plasticity (HSP) in response to chronic activity blockade, and prior work has established that it is released from glia. Here we demonstr...
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It was a great pleasure to present our work on ultrasound BBB-opening and nanobody delivery at the 3rd ECR workshop of #CUREND last week ! Great science and networking event ! @InstitutCerveau @BenoitDelatour
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Another postdoc position available for those with more neurodegenerative disease focused neuromodulation folks.
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Great opportunity 👇👇👇
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Thrilled to see this work from my @MSCActions finally out. Great team work coming from @abhay_curam' lab at @CURAMdevices. If you are interested in CBD formulations and their potential to tackle inflammatory process in ischemic events in the brain, please take a look
Glad to see our work studying how promising CBD-loaded nanoparticles can be in tackling neuroinflammation associated with ischemic stroke already published! Take a look 👇🏻 @CURAMdevices @MedTrainFellows
https://t.co/e0Uc2Bkq0x
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The first person to receive a brain-monitoring device from Neuralink can control a computer cursor with their mind, Elon Musk revealed this week Researchers say this is not a major feat — and they are concerned about the secrecy around the device’s safety
nature.com
Nature - Elon Musk announced this week that his company’s brain implant has allowed a person to move a computer mouse with their mind.
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