Alan Park
@APNeuro
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Neuroscientist seeking to understand our mind #NARSAD Young Investigator @SNUnow @Columbia @ZuckermanBrain @Penn
Seoul, Korea
Joined January 2021
I am pleased to share that I started my lab at the Seoul National University College of Medicine in Korea in September 2022! Please check out my lab website
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Dynamic Interplay between Prefrontal Theta and Beta Bursts Facilitates Flexible Learning https://t.co/nc20HoyhgU
#neuroscience
en-journal.org
Hahyeon Park, Haseong Kim, Eunyoung Yeo and Alan Jung Park. Exp Neurobiol -0001;0:. https://doi.org/10.5607/en25034
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Rapid, biochemical tagging of cellular activity history in vivo
biorxiv.org
Intracellular calcium (Ca2+) is ubiquitous to cell signaling across all biology. While existing fluorescent sensors and reporters can detect activated cells with elevated Ca2+ levels, these approac...
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New paper online! In 2018, we found a human brain signal that tracks real time fluctuations in mood/anxiety. Now Adam Jackson back-translates this biomarker to mice, dissects its circuit mechanisms, & tests its causal relationship to emotional state. 🧵1/6
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New tools from my lab. Due to Minju Jeong's extensive efforts to validate the tools and Jun-Hyeok Choi's ingenious molecular design, we can now present additional methods to identify and modulate specific neuronal populations. https://t.co/w7NNrZPzq3
cell.com
Jeong et al. created a new viral technique, ΦC31/pSIO vector, to target specific neuronal cell types without cross-reactivity with Cre and Flp recombinases. These easy-to-use viral tools for robust...
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Check out our new preprint on neural signatures of stress susceptibility and resilience in the amygdala-ventral hippocampal network! https://t.co/sYSA8K5dkP Thread below 👇
biorxiv.org
The neural dynamics that underlie divergent anhedonic responses to stress remain unclear. Here, we identified neuronal dynamics in an amygdala-hippocampal circuit that distinguish stress resilience...
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New paper from lab: A VPA-induced mouse model of ASD shows dysregulation of Wnt signaling through upregulation of RNF146 in PFC. https://t.co/BVImJFxCJK Great team efforts with @joonomics, Drs. Min-Sik Kim and Chan Young Shin. Congrats @gogogaeun0624 and all authors!
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Highly recommend the Stujenske lab! I was a postdoc when he was a student, and I learned a lot from him.
💼 Tech, grad student, and postdoc positions available 💡 Explore the circuit basis of emotional control! 🤝 I am passionate about mentorship and teaching 🔬 Learn cutting-edge techniques: in vivo 2p imaging, electrophysiology, behavior and physiology tracking, optogenetics
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✨Exciting news! Our research on parallel decision computations is just out in @NatureNeuro ! https://t.co/pFYSULVg02 With it, here goes my first attempt at a #tweetprint ! 🧵
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Neurogliaform cells dynamically decouple neuronal synchrony between brain areas
science.org
Input selection in brain neuronal networks involves a local inhibitory cell that can decouple neuronal synchrony selectively and temporarily.
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Awesome work by @yongseoklee7 and @SangJeongKim1. The Cerebellum plays a role in fear memory.
Excited to share our new paper published in @CellReports. We show that the cerebellum modulates fear memory via its projection to the parabrachial nucleus. Thanks and congrats to my colleagues, especially Kyoung-Doo (tweeterless) and @SangJeongKim1!
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Dual-polarity voltage imaging of the concurrent dynamics of multiple neuron types Article: https://t.co/etZPpuB1ce Awesome!
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1/18 Our paper on reward expectation, spatial encoding, and dopamine inputs to CA1 is finally out! Huge shout out to co-first authors twitterless postdoc Seetha Krishnan and grad student Chad Heer and our former lab tech Chery Cherian.
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We have a study out today on a new circuit that encodes information about reward that I am very excited to share from Twitterless lead author Wenliang Zhou. Time for a Tweet walk https://t.co/hMvBXk2EiV 1/20
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Very happy to announce the publication of my first first-author paper in @CellReports! We find that ramping and phasic dopamine neuron activity reflect reward prediction error, improving goal-directed navigation. Thread (1/8) 👇 https://t.co/UdJBrxIHpk
cell.com
Dopamine neurons signal reward prediction error in their phasic activity, but reports of ramping activity and its potential function remain controversial. Using experimental and computational...
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Our preprint examining hippocampal dynamics during learning is up https://t.co/rE0TyAV2eU Interested in learning? Information processing by neural ensembles? Division of function across subnetworks? The hippocampus? Come along for a quick look at some highlights… 1/n
biorxiv.org
Animals associate cues with outcomes and continually update these associations as new information is presented. The hippocampus is crucial for this, yet how neurons track changes in cue-outcome...
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Proud to be a part of a group that just published in @Nature a role for CCR5 in closing the temporal window for linking memories by modulating excitability and memory ensemble overlap. Also, CCR5 increases account for age-related loss in memory linking! https://t.co/yHULmVTHwL
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