Yu-Sheng Yeh
@yushengyeh
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Joined June 2014
Historic night for VMI/HVI & Pitt at #AHA25. 3 trainees (@yushengyeh in @RazaniLab and @AKirillova0424 and Yinan Shi in Chan lab) competed for early career awards across BCVS, GPM, & 3CPR councils. Anna and Yinan both won. @PittVMI @PittDeptofMed @HviUpmc @PittCMU_MSTP are proud!
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Proud of Terrific Trio @RazaniLab Postdocs make strong showing at #AHA25 NOLA this week: @yushengyeh competes as finalist in #BCVS Katz Basic Science Research Prize. @Ziyang_LiuPhD presents #Galectin3 & @AliiAjam #cholesterol #mtor work at VB.MDP.15/16 & ATVB Council Reception 🔥
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Happy to share our new paper in @Nature led by staff scientist Xuejing Liu @Jessielxj2. We report identification of a UCP1-independent pathway of brown fat thermogenesis involving ATP-consuming metabolism of BCFA in peroxisomes. #Obesity #T2D
https://t.co/9NBWQxrRYc
@WashUDeptMed
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Blocking #CD47 has emerged as promising therapy in #CVD. Check out work in @CircAHA by Zhen Guo of @Alicardsdoc lab identifying CD47 in #cardiomyopathy #heartfailure induced by doxorubicin & targeting it as novel therapy. Great partnering with you on this. https://t.co/53HoToyvIj
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Congrats to Dr. Shingo Kajimura, recipient of the Outstanding Scientific Achievement Award #ADA2025 whose talk, “An unexpected journey into brown fat research for metabolic health”, just ended #ADASciSession! Happy to have journeyed with him! @AtUcsf @KajimuraLab @AmDiabetesAssn
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News flash #trehalose aficionados: New work by @yushengyeh and @RazaniLab team shows this natural sugar inducing #autophagy #TFEB to treat #obesity #metabolism & other diseases is NOT effective by oral route and KO of gut enzyme #trehalase doesn't help. https://t.co/JeZkN1UPXB
frontiersin.org
Trehalose is a naturally occurring disaccharide with versatile commercial applications and health benefits, including promise as a therapeutic for obesity an...
New Research: Assessing the efficacy of the natural disaccharide trehalose in ameliorating diet-induced obesity and metabolic dysfunction https://t.co/9TPfiMNGA9
#FrontiersIn #Nutrition
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Mitochondria-organelle crosstalk in establishing compartmentalized metabolic homeostasis @BrandonTWChen @LyssiotisLab @Yatrikshahlab @MolecularCell
cell.com
Mitochondria are metabolic hubs that communicate with other organelles via metabolite-, lipid-, and signaling-molecule exchange facilitated by membrane contact sites (MCSs). MCSs, regulated by...
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Spilling the skinny on fat cells! @RazaniLab & team @pitt_medicine and @UPMC discover the process for adaptation to fasting and cold-induced lipolysis involves lysosomal lipolysis: https://t.co/UCR3kIBEPR
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Spilling the skinny on fat cells! ASCI member Babak Razani @RazaniLab & team @pitt_medicine discover the process for adaptation to fasting and cold-induced lipolysis involves lysosomal lipolysis: https://t.co/AQUSh8Bevq
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Wondered how #adipocyte #fat release #lipid via #lipolysis in #fasting, cold exposure? Multi-year @Razanilab effort in @jclinicalinvest by postdoc maven @yushengyeh identifies #lysosome lipolysis (LAL) as major way on par with known cytosolic route (ATGL) https://t.co/ThtJuPgVUy
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2/ AHA Early Innovators Spotlight 1 - Basic Science @SumitaD00265928 @LiviaStanger @yushengyeh @LingarajuAmulya
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