
Joseph Wade
@wade_lab
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Bacterial genetics/genomics/gene regulation/CRISPR. Tweets by Joe.
Albany, NY
Joined September 2017
RT @GalaganLab: 🚨 Our BoltzNet paper is out @NatureComms!. We are excited to provide a website with access to all m….
nature.com
Nature Communications - The authors describe BoltzNet, a neural network that learns the energy of transcription factor (TF)-DNA binding from genomic data and can be used to design new binding...
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RT @UAlbanyCIHS: In 1985, the former School of Public Health was created by Health Commissioner David Axelrod in partnership with UAlbany t….
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RT @biorxiv_micrbio: CRISPR-Cas supervises diverse anti-phage defense systems #biorxiv_micrbio.
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RT @biorxiv_micrbio: A phage-encoded counter-defense inhibits an NAD-degrading anti-phage defense system #biorxiv_….
biorxiv.org
Bacteria contain a diverse array of genes that provide defense against predation by phages. Anti-phage defense genes are frequently located on mobile genetic elements and spread through horizontal...
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RT @GeiselBiofilm: New in JB: Oshiro, Seed et al. uncover a novel mechanism to overcome the BREX phage defense system by targeting the BrxC….
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RT @biorxiv_micrbio: A bacterial NLR-related protein recognizes multiple unrelated phage triggers to sense infection .
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RT @biorxiv_micrbio: A Salmonella enterica serovar Typhimurium Genome-wide CRISPRi Screen Reveals a Role for Type 1 Fimbriae in Evasion of….
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RT @bms_ualbany: Congratulations Sam! . Today, Samantha Lindberg defended her thesis; “Antibody-mediated multicellular behaviors of Salmone….
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RT @biorxiv_micrbio: Evolution of PqsE as a Pseudomonas aeruginosa-specific regulator of LuxR-type receptors: insights from Pseudomonas and….
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RT @biorxiv_micrbio: PqsE acts as an adaptor protein for the quorum-sensing transcription factor RhlR in Pseudomonas aeruginosa https://t.….
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RT @GraingerLab: Giving these another airing. projects on bacterial pathogens, antimicrobial resistance, and basic mechanisms. all with….
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RT @DrPhilipAdams: 🚨It’s been a long time coming, but….using my first B. burgdorferi strain as a grad student — 11 years ago — now @NatureC….
nature.com
Nature Communications - The control of flagellar synthesis and function in the Lyme spirochete Borrelia burgdorferi is poorly understood, as this pathogen lacks the typical flagellar sigma factor...
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RT @AlbertW_Lab: We are excited to share our latest work on the cooperation between RNA polymerase and the ribosome in bacteria: https://t.….
science.org
Protein synthesis begins with the formation of a ribosome-messenger RNA (mRNA) complex. In bacteria, the small ribosomal subunit (30S) is recruited to many mRNAs through base pairing with the...
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RT @biorxiv_micrbio: A Novel Actinobacteria-Specific Ribosome Hibernation Factor in Mycobacterium tuberculosis #bi….
biorxiv.org
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), persists within its host for long periods. Treatment of TB requires prolonged administration of antibiotics, some of which...
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RT @MBlokesch: Exciting times! Our latest preprint is now live 🤩!.I truly believe this is one of the most significant contributions we've m….
biorxiv.org
Our understanding of the factors underlying the evolutionary success of different lineages of pandemic Vibrio cholerae remains incomplete. Interestingly, two unique genetic signatures define the West...
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RT @IMIBirmingham: PhD projects available in @GraingerLab All focus on bacterial gene regulation, in the context of basic understanding, di….
findaphd.com
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RT @Helmholtz_HIRI: A new research briefing has just been published in @NatureBiotech, summarizing the latest paper from #HIRI's @BeiselLab….
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RT @AldridgeLab: Tap tap…is the🎙️ still on? This work has been in the works for a long time! We studied the growth behaviors and cell cycle….
nature.com
Nature Microbiology - Time-lapse imaging of Mycobacterium tuberculosis cells loaded in microfluidic chambers reveals heterogeneity in growth characteristics, atypical modes of polar growth...
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RT @JoePetersLab: @CedricFeschotte @PopoMicro Our preprint for this work is now on bioRxiv. This work also reveals a new type of guide RNA….
biorxiv.org
Eukaryotes have linear DNA and their telomeres are hotspots for transposons, which in some cases took over telomere maintenance. While many bacteria also have linear chromosomes and plasmids, no...
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